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Pubertal development may predispose women to pain and other symptoms

sexes, pubertal development was a better predictor of pain than was age.

Thus it appears that pain, other somatic symptoms and depression increase systematically with pubertal development in girls. These results confirm that the prevalence of pain conditions in adolescents, particularly adolescent girls, is substantial. In addition, the authors found that physical development as well as gender, is associated with the experience of pain in adolescents. Specifically, in girls, pubertal development was related not only to the probability of experiencing specific pain conditions, but also to the probability of experiencing multiple pain problems. The probability of experiencing significant levels of non-pain physical symptoms, as well as depressive symptoms, also increased with pubertal development in girls.

These findings suggest that the process of pubertal development may initiate biological changes that predispose women, in particular, to experience symptoms, including pain.
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