Navigation Links
Proteinomics Research holds Key to Stomach Cancer

A multi-national research team led by the Melbourne Branch of the Ludwig Institute for Cancer Research// has identified a potential new target for stomach cancer therapy, according to a paper published today.

Professor Brendan Jenkins and his colleagues from the Ludwig Instiute for Cancer Research, Melbourne has identified a particular potential new target which can be targeted for stomach cancer therapy. The result has been published in Nature Medicine Journal.

Dr. Brendan Jenkins says that this single study has made several substantial contributions to the understanding of Stat3, the protein linking those ‘genes behaving badly’ and central to development, tissue equilibrium and the immune system. “We showed that, in mice, hyperactive Stat3 shuts down a vital controller of stomach cell growth, called TGF beta, and this allows cancer formation, and this mechanistic link is a world-first. Also, the gene differences identified in human stomach cancers are similar to those we would predict if the same thing, Stat3 hyperactivity shutting down TGF, happens in humans. So this is also the first time a connection between stomach cancer and this signaling pathway has been made.”

It is found that these basic research findings demonstrates that by lowering the Stat3 hyperactivity, we can suppress stomach cancer formation, importantly without affecting Stat3’s other important roles in the body. Add to that the evidence suggesting that Stat3 is also involved in breast, head and neck, and prostate cancers, and we have a compelling case for investigating the development of therapies that target Stat3.”

(Source: Newswise)



More information on Stomach cancer in Medindia: Surgery is the most common treatment for stomach cancer. The operation is called gastrectomy. The surgeon removes part (subtotal or partial gastrectomy) or all (total gastrectomy) of the stomach, as well as some of the tissue arou nd the stomach. After a subtotal gastrectomy, the doctor connects the remaining part of the stomach to the esophagus or the small intestine. After a total gastrectomy, the doctor connects the esophagus directly to the small intestine.

For more information:
http://www.medindia.net/Patients/
PatientInfo/gastriccancer.htm

'"/>




Related medicine news :


1. Kidney Stones - Interesting New Research implicates bacteria as its cause
2. Researchers urge caution in using ear tube surgery
3. Paracetamol May Cause Live Damage Warns Consumer Education and Research Centre
4. Researchers Scale to assess the Severity of Epilepsy in Kids
5. Research of Ritalin
6. Researchers trick Alzheimers Enzyme
7. Researchers find new HIV hiding place
8. A Compilation of recent Diabetes Research articles
9. Research on causes for falling helps develop preventive strategies
10. New standards for Human Research Safety
11. Research on Celiac Disease in children
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/18/2017)... MANDEVILLE, La. (PRWEB) , ... February 18, 2017 ... ... Network released today provides the latest information and contact points to easily connect ... including home care, assisted living, and elder-care funding. It also conveys material on ...
(Date:2/17/2017)... ... February 17, 2017 , ... While EHR data ... has introduced an innovative workstation designed to reduce nursing fatigue while enhancing productivity. ... EHR Workstation offers a lightweight, highly mobile, multi-functional alternative to the limitations of ...
(Date:2/17/2017)... ... February 17, 2017 , ... Wells Pharmacy Network ... prescribing of controlled and non-controlled substances plus the ability to manage orders on ... United States now accept electronic prescriptions, according to the Office of the National ...
(Date:2/17/2017)... Falls Church, VA (PRWEB) , ... ... ... to Integrate FDA Device Approval and Reimbursement , **An FDAnews Webinar**, Feb. ... , What are the critical reimbursement questions manufacturers should be asking ...
(Date:2/17/2017)... Falls Church, VA (PRWEB) , ... February 17, ... ... Devices, Implementing the Steps to Prevent a Warning Letter, **An FDAnews Webinar**, Feb. ... , Do manufacturers distinguish between corrective action (CA) and preventive action ...
Breaking Medicine News(10 mins):
(Date:2/17/2017)... Company plc (NYSE, TASE: PRGO) today announced it has received ... hydrocodone bitartrate and homatropine methylbromide oral solution (syrup), 5 mg/1.5 ... homatropine methylbromide oral solution (syrup), 5 mg/1.5 mg per 5 ... adults and children 6 years of age and older. Annual ... $16 million.   ...
(Date:2/17/2017)... Feb. 17, 2017   FormFast , the leader ... new partnership with Engage , one of the ... . FormFast will serve as the forms automation ... with MEDITECH .  FormFast is ... to complement and enhance the electronic health record. FormFast,s ...
(Date:2/16/2017)... Feb. 16, 2017 Absorption Systems, a global ... devices, is pleased to announce that its Chief Operating ... as a winner of the 2017 Executive Management Award. ... and recognizes driven executives for their creative management vision, ... awards ceremony and celebration is on March 8, 2017 ...
Breaking Medicine Technology: