Navigation Links
Proteinomics Research holds Key to Stomach Cancer

A multi-national research team led by the Melbourne Branch of the Ludwig Institute for Cancer Research// has identified a potential new target for stomach cancer therapy, according to a paper published today.

Professor Brendan Jenkins and his colleagues from the Ludwig Instiute for Cancer Research, Melbourne has identified a particular potential new target which can be targeted for stomach cancer therapy. The result has been published in Nature Medicine Journal.

Dr. Brendan Jenkins says that this single study has made several substantial contributions to the understanding of Stat3, the protein linking those ‘genes behaving badly’ and central to development, tissue equilibrium and the immune system. “We showed that, in mice, hyperactive Stat3 shuts down a vital controller of stomach cell growth, called TGF beta, and this allows cancer formation, and this mechanistic link is a world-first. Also, the gene differences identified in human stomach cancers are similar to those we would predict if the same thing, Stat3 hyperactivity shutting down TGF, happens in humans. So this is also the first time a connection between stomach cancer and this signaling pathway has been made.”

It is found that these basic research findings demonstrates that by lowering the Stat3 hyperactivity, we can suppress stomach cancer formation, importantly without affecting Stat3’s other important roles in the body. Add to that the evidence suggesting that Stat3 is also involved in breast, head and neck, and prostate cancers, and we have a compelling case for investigating the development of therapies that target Stat3.”

(Source: Newswise)



More information on Stomach cancer in Medindia: Surgery is the most common treatment for stomach cancer. The operation is called gastrectomy. The surgeon removes part (subtotal or partial gastrectomy) or all (total gastrectomy) of the stomach, as well as some of the tissue arou nd the stomach. After a subtotal gastrectomy, the doctor connects the remaining part of the stomach to the esophagus or the small intestine. After a total gastrectomy, the doctor connects the esophagus directly to the small intestine.

For more information:
http://www.medindia.net/Patients/
PatientInfo/gastriccancer.htm

'"/>




Related medicine news :


1. Kidney Stones - Interesting New Research implicates bacteria as its cause
2. Researchers urge caution in using ear tube surgery
3. Paracetamol May Cause Live Damage Warns Consumer Education and Research Centre
4. Researchers Scale to assess the Severity of Epilepsy in Kids
5. Research of Ritalin
6. Researchers trick Alzheimers Enzyme
7. Researchers find new HIV hiding place
8. A Compilation of recent Diabetes Research articles
9. Research on causes for falling helps develop preventive strategies
10. New standards for Human Research Safety
11. Research on Celiac Disease in children
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/18/2017)... Missouri (PRWEB) , ... August 18, 2017 , ... “Emotions ... Suzanne Tucker, Founder of St. Louis-based positive education company Generation Mindful. To help change ... help children learn social and emotional skills, she created the Time-In Toolkit, which launched ...
(Date:8/18/2017)... ... August 18, 2017 , ... ... tracking and monitoring solutions, announced today the launch of a redesigned corporate website, ... navigation and aesthetic, fully responsive design, and an enhanced search directory for businesses ...
(Date:8/18/2017)... ... , ... “Depressed: Super Heroes of the Bible”: a gripping and potent ... the relevance these tales may have on the reader’s life. “Depressed: Super Heroes of ... teacher, Jessica spends much of her time enjoying nature and her family in West ...
(Date:8/18/2017)... ... August 18, 2017 , ... “Case #10-5411 Veterans ... Medical Center. “Case #10-5411 Veterans Administration” is the creation of published author, ... In June 1990, Carol Mulhem started work at the Coatesville VAMC as a ...
(Date:8/17/2017)... ... August 17, 2017 , ... Industry CEOs, ... 2017 for Anti-Infectives Rx. This off-the-record networking forum of the Boston Biotech Conference ... Medical School. , Industry leaders and decision makers will discuss issues facing the ...
Breaking Medicine News(10 mins):
(Date:8/2/2017)... and BENTON, Ky. , Aug. 2, 2017   Marshall County Hospital ... environmental services (ES) team to proactively reduce the risk of hospital-acquired infections (HAIs). The new ... robot that uses UVC light energy to kill deadly pathogens such as C. diff ... Tru-D SmartUVC ... Tru-D in action in a ...
(Date:8/1/2017)... --  CerSci Therapeutics , a non-opioid drug development firm ... received notice from the National Institute on Drug Abuse ... it has been awarded a Direct-to-Phase II Small Business ... with an additional $1,000,000 to follow in 2018. These ... their lead non-opioid drug candidate CT-044 to the Food ...
(Date:7/31/2017)... Surgical, developer of ground breaking surgical navigation technologies, announced today ... support its strategic sales plan in Maryland ... Surgical has entered into an exclusive sales representative agreement with ... those markets. ... Spartan Medical Purchases 7D Surgical Technology ...
Breaking Medicine Technology: