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Protein Molecules in blood predict preeclampsia development

fere with to treat the disease," Dr. Levine said.

A possible treatment for preeclampsia might involve reducing levels of sFlt1 or soluble endoglin or adding more of the molecules that they remove from the blood stream, Dr. Levine added, so that more VEGF, PlGF, and TGF beta would be available for the blood vessels that need them. One company has developed the means to produce a form of VEGF. Presumably, such a drug would raise the levels of circulating VEGF in the bloodstream. The surplus VEGF would bind to the high levels of sFlt1 produced during preeclampsia, but enough free VEGF would still be available to attach to cell surface receptors to promote the health of blood vessels.

Dr. Levine cautioned, however, that such attempts to develop a drug treatment would need to proceed cautiously. It's possible that restoring normal blood pressure and blood flow to the mother's circulatory system might deprive the fetus of blood.

Source-Eurekalert
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