Navigation Links
Protein Molecules in blood predict preeclampsia development

ot in women with high levels of only one or the other."

Dr. Levine added that detecting high levels of both soluble endoglin and sFlt1 early in pregnancy might be especially helpful in predicting the later development of preeclampsia. Detecting high levels of these molecules might also help in distinguishing preeclampsia from chronic high blood pressure, kidney disease and other conditions that can produce symptoms similar to preeclampsia.

Dr. Levine said that both sFlt1 and soluble endoglin are referred to as soluble because they circulate in the bloodstream. Both molecules exist in a non-soluble form, attached to the surface of cells lining blood vessels. In this non-soluble form, they are classified as receptors because they serve as targets for other molecules. When molecules attach, or bind, to the receptors, the binding process initiates a chain of events in the cells. PlGF binds to Flt1 on the lining of blood vessels. Another substance, vascular endothelial growth factor (VEGF) also binds to Flt1. This binding process is essential to keeping blood vessels healthy and maintaining normal blood pressure. Similarly, a molecule known as transforming growth factor beta (TGF beta) binds to endoglin, and this binding is also required to keep blood vessels healthy.

Dr. Levine explained that the prevailing theory holds that, when the placenta isn't able to absorb sufficient oxygen from the mother's blood, it begins secreting both sFlt1 and soluble endoglin into the mother's bloodstream. The sFlt1 binds to VEGF and PlGF and soluble endoglin binds TGF beta, diverting the compounds from the mother's blood vessels. In response, the mother's blood pressure rises, forcing more blood to the placenta. High levels of sFlt1 and soluble endoglin result in severe forms of preeclampsia.

"We've found specific molecules that appear to be causing the clinical signs of preeclampsia and so we now have an idea which molecules we would need to inter
'"/>




Page: 1 2 3 4

Related medicine news :

1. Lean Protein Could Be Key to Obesity Drugs
2. Evidence Links Protein Damage to Neurodegenerative diseases like Parkinsons and Alzheimers
3. Unravelling the secrets of ‘Huntingtin’ Protein - towards the treatment of ‘Huntingtons’ Disase
4. Unravelling the secrets of ‘Huntingtin’ Protein - towards the treatment of Huntingtins’ Disese
5. Protein in urine foresees heart disease
6. Levels Of Blood Proteins May Help Heart Disease Care
7. Protein signals need for heart surgery
8. Protein and fat improve memory
9. Clotting Protein plays a role in nerve repair
10. High Levels of Protein Linked to Brain Shrinkage
11. Protein can change worn muscle fibres
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Protein Molecules blood predict preeclampsia development

(Date:12/20/2014)... (PRWEB) December 20, 2014 Xarelto ... they suffered uncontrollable bleeding and other serious side ... Eastern District of Louisiana for coordinated pretrial proceedings, Wright ... Multidistrict Litigation (JPML) issued an order Friday to transfer ... pending in 22 federal courts to the Louisiana district ...
(Date:12/19/2014)... Balfleet.com , a leading dress company of wedding ... All the old and new customers can get a ... well-known for its high quality trendy women’s dresses, like ... more. Its formal dresses are quality made and come ... an elegant look when paired with any accessory. ...
(Date:12/19/2014)... 2014 Energy Textiles is excited ... available. Celliant, the world’s leading responsive textile, can ... , There are a number of benefits to ... oxygenation and balanced body temperature; which can lead ... relief; enhanced athletic performance; and overall wellness. In ...
(Date:12/19/2014)... Eufaula, Oklahoma, located just 9 miles from Narconon ... lake with more than 600 miles of shoreline. ... more than 3,000 residents, hosted its annual old-fashioned holiday ... December. , Featuring Santa, Christmas lights and parade floats, ... Street. Narconon Arrowhead’s parade float participated in this ...
(Date:12/19/2014)... The print component of Vision and Hearing is distributed ... Star, with a circulation of approximately 230,433 copies and ... distributed nationally through a vast social media strategy and ... outlets. To explore the digital version of the campaign, ... an exclusive interview with Mark DeMontis , sharing his ...
Breaking Medicine News(10 mins):Health News:Xarelto Bleeding Lawsuits Consolidated To Louisiana Federal Court For Multi-District Litigation Reports Wright & Schulte LLC 2Health News:Xarelto Bleeding Lawsuits Consolidated To Louisiana Federal Court For Multi-District Litigation Reports Wright & Schulte LLC 3Health News:Xarelto Bleeding Lawsuits Consolidated To Louisiana Federal Court For Multi-District Litigation Reports Wright & Schulte LLC 4Health News:Balfleet.com Announces Its Formal Dress Promotion For 2015 2Health News:Energy Textiles Launches Celliant Revitalizing Bedsheets 2Health News:Narconon Arrowhead Debuts Float at Checotah and Eufaula Christmas Parades 2Health News:Narconon Arrowhead Debuts Float at Checotah and Eufaula Christmas Parades 3Health News:Mark DeMontis, Founder of Courage Canada, shares his passion for bringing hockey to those affected by blindness in Mediaplanet’s “Vision and Hearing” campaign 2
... clues to the impact of severe physical, psychosocial suffering, ... Among Jewish survivors of World War II, those who ... risk of cancer, likely due to physical and mental ... Haifa researchers compared cancer rates in more than 300,000 ...
... women, wide waists in men spell trouble, study finds , ... body fat appears to affect the risk of dangerous blood ... women, a new Danish study indicates. , The 10-year study ... of venous thromboembolism (VTE) in women but not men, while ...
... habits can stave off the inevitable declines, research finds , ... that accompany growing old typically speed up after the age ... can slow the inevitable by staying lean, exercising and refraining ... issue of the Archives of Internal Medicine , are ...
... say , MONDAY, Oct. 26 (HealthDay News) -- There,s ... the family safe on Halloween. Some simple precautions will ... , The American Academy of Pediatrics offers the following ... and reflective and short enough to prevent tripping, entanglement ...
... shows they have doubled risk of GERD, may be linked ... World Trade Center rescue workers can add another illness to ... exposure to Ground Zero toxins and the ensuing mental anguish ... A new study shows that 41 percent of World Trade ...
... Oct. 26 Uno Chicago Grill®, America,s Healthiest Chain Restaurant(1), ... fall menu. , This exciting fall menu stars ... are a well-known and popular accent to many dishes, UNO ... the territory of a select few health food aficionados. ...
Cached Medicine News:Health News:Exposure to Holocaust May Have Raised Cancer Risks 2Health News:Where You Put on Pounds May Influence Clot Risk 2Health News:Fitness Fades Fast After 45 2Health News:Fitness Fades Fast After 45 3Health News:Treat Kids to a Safe Halloween 2Health News:World Trade Center Workers Have More Cases of Acid Reflux 2Health News:World Trade Center Workers Have More Cases of Acid Reflux 3Health News:Go, Go, Goji! UNO(R) Fall Menu Is 'Berry' Delicious 2Health News:Go, Go, Goji! UNO(R) Fall Menu Is 'Berry' Delicious 3
(Date:12/19/2014)... the Friday, December 19 edition of USA ... (HIT) features Konica Minolta, the company announced today. The supplement will ... healthcare organizations. In addition to the print section ... New York , Chicago , ... Minneapolis and San Francisco , ...
(Date:12/19/2014)... TODAY, AEGATE, the leader in medicine verification ... of Peter Fox as Chief Technology Officer ... Officer. Peter has served as Development Director ... Oracle in 2011. Prior to Datanomic, Peter ... and subsequently Convergys, a world renowned billing system for ...
(Date:12/19/2014)... 2014  Newport Corporation (NASDAQ: NEWP ... joined the company,s Board of Directors.  Dr. Kadia ... director of Evans Analytical Group, a leading global ... services to companies in a wide range of ... Analytical Group, Dr. Kadia spent nine years with ...
Breaking Medicine Technology:USA Today Supplement Featuring Konica Minolta Focuses on Impact of Healthcare IT 2Aegate Appoints new CTO and Chief Channels & Partner Officer 2Aegate Appoints new CTO and Chief Channels & Partner Officer 3Aegate Appoints new CTO and Chief Channels & Partner Officer 4Siddhartha Kadia, Ph.D. Joins Board of Directors of Newport Corporation 2
... HARBIN, China , July 1 /PRNewswire-Asia-FirstCall/ ... manufacturer and distributor of botanical products,bio-pharmaceuticals and traditional Chinese medicines, today ... the NYSE Amex. , , ... Renhuang expects to begin trading on ...
... BOSTON , July 1 China PharmaHub Corp. ("PharmaHub"), ... David Weaver and Dr. Michael Rynkiewicz .  In addition, ... of which it recently purchased a 77% interest.   , ... The management of World Wide Relics ("WWR") ...
Cached Medicine Technology:Renhuang Pharmaceuticals Receives Approval to List on the NYSE Amex 2Renhuang Pharmaceuticals Receives Approval to List on the NYSE Amex 3China PharmaHub Corp. Enters Into Definitive Agreement for Humanized Antibody 2China PharmaHub Corp. Enters Into Definitive Agreement for Humanized Antibody 3China PharmaHub Corp. Enters Into Definitive Agreement for Humanized Antibody 4
The Fluoroskan Ascent, a dedicated microplate fluorometer, offers high sensitivity for a wide variety of fluorometric applications....
The VersaFluor cuvette fluorometer is a fast and simple way to quantitate DNA, RNA, and proteins, to detect apoptosis, and to perform reporter enzyme assays with the high level of sensitivity and sel...
... unique microprocessor-controlled filter wheels for wavelength selection ... filter wheels can be programmed for excitation ... With this fluorometer, you do not have ... wavelengths. The C&L Dye Fluorometer can measure ...
The TBS-380 Fluorometer is an economical, sensitive fluorometer designed for quick, easy, and accurate fluorescent measurements....
Medicine Products: