Navigation Links
Protein Linking Vitamin E And Prostate Cancer

Researchers at the University of Rochester have identified a protein that promotes vitamin E’s retention in prostate cells, thereby slowing the development of prostate cancer//.

The protein called alpha tocopherol associated protein, or TAP, is known to play a vital role in the synthesis of cholesterol in the liver. Cholesterol plays a significant role in the development of heart disease and is nearly always implicated in heart attacks.

But this is the first time that its association with suppressing the growth of prostate cancer has come to light. The team of researchers led by ShuYuan Yeh, assistant professor of urology and pathology also found that TAP also increases the retention of Vitamin E in the prostate cells and appears to disrupt a signaling pathway in prostate cancer cells.

“Vitamin E and TAP have distinct pathways to modulate prostate cancer cell growth and we hypothesize that vitamin E and TAP can work together to elicit better tumor suppression effects,” the researchers note in the study, which appears in the 1 November issue of Cancer Research.

They found that when compared to normal prostate tissue, which had high levels of TAP; human prostate cancer tissue had reduced levels of the protein. The same finding was also seen in several prostate cancer cell lines tested by the researchers. As far as the exact mechanism was concerned, the researchers say that Vitamin E disrupted the pathway by which prostate cancer cells synthesize prostate-specific antigen (PSA) and the androgen receptor. Both these steps are vital in the development and progression of the cancer. “No one really knows how vitamin E works. TAP may give us insights into how vitamin E works anywhere in the body and why it is a required vitamin,” observed Edward Messing, a co-author of the stud.
'"/>




Page: 1

Related medicine news :

1. Lean Protein Could Be Key to Obesity Drugs
2. Evidence Links Protein Damage to Neurodegenerative diseases like Parkinsons and Alzheimers
3. Unravelling the secrets of ‘Huntingtin’ Protein - towards the treatment of ‘Huntingtons’ Disase
4. Unravelling the secrets of ‘Huntingtin’ Protein - towards the treatment of Huntingtins’ Disese
5. Protein in urine foresees heart disease
6. Levels Of Blood Proteins May Help Heart Disease Care
7. Protein signals need for heart surgery
8. Protein and fat improve memory
9. Clotting Protein plays a role in nerve repair
10. High Levels of Protein Linked to Brain Shrinkage
11. Protein can change worn muscle fibres
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:12/4/2016)... ... December 03, 2016 , ... ... to funding innovative lymphoma research and serving the lymphoma community through a comprehensive ... Swirl: A Wine Tasting Event in New York City, with long-time partners The ...
(Date:12/4/2016)... ... ... While James Earl Jones is known for myriad roles on stage and ... Page". One of the forthcoming episodes examines mammogram techniques; a very important part of ... due to early detection. Like any other disease, treatments have a much higher chance ...
(Date:12/4/2016)... , ... December 03, 2016 , ... ... growing Entrepreneurial Company in the Dallas area” Tuesday evening at the 26th Annual ... Hotel, presented by SMU's Cox School’s Caruth Institute for Entrepreneurship. Dallas 100™, co-founded ...
(Date:12/4/2016)... Newport Beach, CA (PRWEB) , ... December 04, ... ... youthful appearance without undergoing major cosmetic surgery can now take advantage of a ... is an advanced skin rejuvenation treatment that reduces the appearance of age spots, ...
(Date:12/4/2016)... ... December 04, 2016 , ... Responsible dental care hinges ... brush properly to achieve optimal results. This important necessity inspired an inventor from Las ... a way to ensure that people break or avoid bad techniques of brushing the ...
Breaking Medicine News(10 mins):
(Date:12/2/2016)... , December 2, 2016 ... "In Vitro Diagnostics/IVD Market by Product (Instruments, Reagents, ... Application (Diabetes, Oncology, Cardiology, Nephrology, Infectious Diseases) - ... market is valued at USD 60.22 Billion in ... a CAGR of 5.5% during the forecast period ...
(Date:12/2/2016)... , Dec. 2, 2016 In the ... sources apart from those derived from C. sativa, the ... Universita` di Napoli Federico II , the Universita` ... the first comprehensive, critical, integrated and unified inventory of ... article focuses on the remarkable chemical and structural ...
(Date:12/2/2016)... INDIANAPOLIS , Dec. 2, 2016  Eli Lilly ... its financial guidance for 2017 and provide updated financial ... will also conduct a conference call on that day ... the company,s financial guidance. The conference call ... the general public can access a live webcast of ...
Breaking Medicine Technology: