Navigation Links
Protein Linking Vitamin E And Prostate Cancer

Researchers at the University of Rochester have identified a protein that promotes vitamin E’s retention in prostate cells, thereby slowing the development of prostate cancer//.

The protein called alpha tocopherol associated protein, or TAP, is known to play a vital role in the synthesis of cholesterol in the liver. Cholesterol plays a significant role in the development of heart disease and is nearly always implicated in heart attacks.

But this is the first time that its association with suppressing the growth of prostate cancer has come to light. The team of researchers led by ShuYuan Yeh, assistant professor of urology and pathology also found that TAP also increases the retention of Vitamin E in the prostate cells and appears to disrupt a signaling pathway in prostate cancer cells.

“Vitamin E and TAP have distinct pathways to modulate prostate cancer cell growth and we hypothesize that vitamin E and TAP can work together to elicit better tumor suppression effects,” the researchers note in the study, which appears in the 1 November issue of Cancer Research.

They found that when compared to normal prostate tissue, which had high levels of TAP; human prostate cancer tissue had reduced levels of the protein. The same finding was also seen in several prostate cancer cell lines tested by the researchers. As far as the exact mechanism was concerned, the researchers say that Vitamin E disrupted the pathway by which prostate cancer cells synthesize prostate-specific antigen (PSA) and the androgen receptor. Both these steps are vital in the development and progression of the cancer. “No one really knows how vitamin E works. TAP may give us insights into how vitamin E works anywhere in the body and why it is a required vitamin,” observed Edward Messing, a co-author of the stud.
'"/>




Page: 1

Related medicine news :

1. Lean Protein Could Be Key to Obesity Drugs
2. Evidence Links Protein Damage to Neurodegenerative diseases like Parkinsons and Alzheimers
3. Unravelling the secrets of ‘Huntingtin’ Protein - towards the treatment of ‘Huntingtons’ Disase
4. Unravelling the secrets of ‘Huntingtin’ Protein - towards the treatment of Huntingtins’ Disese
5. Protein in urine foresees heart disease
6. Levels Of Blood Proteins May Help Heart Disease Care
7. Protein signals need for heart surgery
8. Protein and fat improve memory
9. Clotting Protein plays a role in nerve repair
10. High Levels of Protein Linked to Brain Shrinkage
11. Protein can change worn muscle fibres
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/26/2016)... ... 2016 , ... PawPaws brand pet supplements owned by Whole Health ... the health of felines. The formula is all-natural and is made from Chinese herbs ... Cat Kidney Support Supplement Soft Chews are Astragalus Root Extract and Rehmannia ...
(Date:6/25/2016)... ... ... The temporary closing of Bruton Memorial Library on June 21 due to a possible lice ... overlooked aspect of head lice: the parasite’s ability to live away from a human host, ... a necessary one in the event that lice have simply gotten out of control. , ...
(Date:6/25/2016)... ... June 25, 2016 , ... On Friday, June 10, Van Mitchell, Secretary of ... award to iHire in recognition of their exemplary accomplishments in worksite health promotion. , ... Workplace Health & Wellness Symposium at the BWI Marriott in Linthicum Heights. iHire was ...
(Date:6/24/2016)... PASADENA, CA (PRWEB) , ... June 24, 2016 , ... Marcy was in a crisis. ... he would lash out at his family verbally and physically. , “When something upset him, ... table, he would use it. He would throw rocks at my other children and say ...
(Date:6/24/2016)... ... ... of Topricin and MyPainAway Pain Relief Products, join The ‘Business for a Fair Minimum Wage’ ... 2020 and then adjusting it yearly to increase at the same rate as the median ... floor does not erode again, and make future increases more predictable. , The company is ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)...  In a startling report released today, National Safety Council ... a comprehensive, proven plan to eliminate prescription opioid overdoses. ... states are tackling the worst drug crisis in recorded U.S. history, ... Kentucky , New Mexico , ... the 28 failing states, three – Michigan , ...
(Date:6/23/2016)... , June 23, 2016 Research and ... News Issue 52" report to their offering. ... influenza treatment creates a favourable commercial environment for MedImmune to ... patient base that will serve to drive considerable growth for ... would serve to cap sales considerably, but development is still ...
(Date:6/23/2016)... and BOGOTA, Colombia , June 23, 2016  Astellas today announced the establishment of ... Farma Brasil as the company,s second affiliate in Latin America . ... ... Manager of Astellas Farma Colombia ... ...
Breaking Medicine Technology: