Navigation Links
Protein Linking Vitamin E And Prostate Cancer

Researchers at the University of Rochester have identified a protein that promotes vitamin E’s retention in prostate cells, thereby slowing the development of prostate cancer//.

The protein called alpha tocopherol associated protein, or TAP, is known to play a vital role in the synthesis of cholesterol in the liver. Cholesterol plays a significant role in the development of heart disease and is nearly always implicated in heart attacks.

But this is the first time that its association with suppressing the growth of prostate cancer has come to light. The team of researchers led by ShuYuan Yeh, assistant professor of urology and pathology also found that TAP also increases the retention of Vitamin E in the prostate cells and appears to disrupt a signaling pathway in prostate cancer cells.

“Vitamin E and TAP have distinct pathways to modulate prostate cancer cell growth and we hypothesize that vitamin E and TAP can work together to elicit better tumor suppression effects,” the researchers note in the study, which appears in the 1 November issue of Cancer Research.

They found that when compared to normal prostate tissue, which had high levels of TAP; human prostate cancer tissue had reduced levels of the protein. The same finding was also seen in several prostate cancer cell lines tested by the researchers. As far as the exact mechanism was concerned, the researchers say that Vitamin E disrupted the pathway by which prostate cancer cells synthesize prostate-specific antigen (PSA) and the androgen receptor. Both these steps are vital in the development and progression of the cancer. “No one really knows how vitamin E works. TAP may give us insights into how vitamin E works anywhere in the body and why it is a required vitamin,” observed Edward Messing, a co-author of the stud.
'"/>




Page: 1

Related medicine news :

1. Lean Protein Could Be Key to Obesity Drugs
2. Evidence Links Protein Damage to Neurodegenerative diseases like Parkinsons and Alzheimers
3. Unravelling the secrets of ‘Huntingtin’ Protein - towards the treatment of ‘Huntingtons’ Disase
4. Unravelling the secrets of ‘Huntingtin’ Protein - towards the treatment of Huntingtins’ Disese
5. Protein in urine foresees heart disease
6. Levels Of Blood Proteins May Help Heart Disease Care
7. Protein signals need for heart surgery
8. Protein and fat improve memory
9. Clotting Protein plays a role in nerve repair
10. High Levels of Protein Linked to Brain Shrinkage
11. Protein can change worn muscle fibres
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:7/20/2017)... ... ... Team Type 1 Foundation, a nonprofit organization pursuing a global mission of education, ... with a Microsoft Corp. employee-led hackathon team for the 2017 Microsoft One Week Hackathon ... 1’s mission overlaps seamlessly with Microsoft’s mission to empower every person and every organization ...
(Date:7/20/2017)... Falls Church, VA (PRWEB) , ... July 20, ... ... Improve Your Bottom Line, **An FDAnews Webinar**, Aug. 9, 2017 — 1:30 p.m. ... a secret weapon to passing inspections and boosting quality. , It’s known as ...
(Date:7/20/2017)... ... July 20, 2017 , ... The Business Architecture Guild® ... Knowledge (BIZBOK® Guide )v 6.0 is now available for member download. This release ... collaborative teams. , Non-members may download the Part 1 Introduction for free ...
(Date:7/20/2017)... ... July 19, 2017 , ... A local summer theatre ... funds raised to support fine arts programs in Chester County’s Elementary Schools. In ... University’s Loyd Auditorium. , More than 850 people attended the two performances, ...
(Date:7/20/2017)... ... 19, 2017 , ... Western University of Health Sciences College ... grant to train predoctoral dental students in providing care to vulnerable children ages ... , The Predoctoral Pediatric Training Project (PPTP), a five-year grant, recognizes the curriculum ...
Breaking Medicine News(10 mins):
(Date:7/10/2017)... July 10, 2017  The tenth annual BioPharm ... MA at the Sheraton Boston Hotel, September ... access to global decision makers and innovative biotech startup ... science leaders during two impactful days. BioPharm America is ... with additional networking opportunities with 4,500+ life science industry ...
(Date:7/5/2017)... of over 2,000 employees and a leader in environmental and life science testing, ... position as the top American owned and operated environmental testing firm in ... ... The ... , enhances Pace Analytical,s capability as an innovative full service provider in the ...
(Date:6/30/2017)... POINT, N.C. , June 29, 2017  Axium Pharmaceuticals Inc. ... for developing improved novel formulations and alternative dosage forms of ... ... delivery is based on our waterless self-nano emulsifying formula, which ... contact with saliva. We believe the spray will provide fast ...
Breaking Medicine Technology: