Navigation Links
Protein Linked To Accelerating Rheumatoid Arthritis

A new study published in the December issue of Arthritis and Rheumatism says that a protein called Type II Collagen (CII) could have a vital role in the pathogenesis of rheumatoid arthritis (RA), a very painful inflammatory // joint condition.

This protein was found by a team of researchers at the Queen Mary's School of Medicine and Dentistry at the University of London. It appears that the protein modifies itself and then proceeds to systematically destroy the body's immune system and concurrently increases inflammation of the joints. These findings could be a pointer towards the development of new drugs to combat the disease.

Type II Collagen (CII) is a major protein found abundantly in cartilage, bone and tendons. The team felt that CII could trigger RA when it is stressed by inflammation. They say that when inflammatory cells enter normal tissue they tend to overuse the oxygen supply. This means that proteins are deprived of this vital element and consequently undergo some modification. To prove this point they took blood samples from 31 male and female RA patients and from 41 patients who had other inflammatory conditions like osteoporosis, back pain and gout. All of these samples were subjected to exposure by CII protein taken from cows as well as a modified CII. This is typically present in rheumatic inflammation. The researchers found that CII did not bind in the blood samples of RA patients. But 45 percent of the RA blood samples formed immune complexes with the altered form of the protein. The researchers say that CII serves to accelerate and already worse condition in RA. "Our study has important implications for the further study and enhanced understanding of the pathology of RA," said study author Ahuva Nissim. "In the future, understanding of this process will help us develop specific therapeutics which will target only the inflamed joints."


'"/>




Page: 1

Related medicine news :

1. Lean Protein Could Be Key to Obesity Drugs
2. Evidence Links Protein Damage to Neurodegenerative diseases like Parkinsons and Alzheimers
3. Unravelling the secrets of ‘Huntingtin’ Protein - towards the treatment of ‘Huntingtons’ Disase
4. Unravelling the secrets of ‘Huntingtin’ Protein - towards the treatment of Huntingtins’ Disese
5. Protein in urine foresees heart disease
6. Levels Of Blood Proteins May Help Heart Disease Care
7. Protein signals need for heart surgery
8. Protein and fat improve memory
9. Clotting Protein plays a role in nerve repair
10. High Levels of Protein Linked to Brain Shrinkage
11. Protein can change worn muscle fibres
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/24/2017)... ... March 24, 2017 , ... ... spark a conversation on the current obstacles facing infection prevention and offer strategies ... deaths caused by these infections. , The print component of “Fighting Infection” ...
(Date:3/24/2017)... (PRWEB) , ... March 24, 2017 , ... According to ... score is invalid because it does not obey the rules Congress has directed the ... equivalent jobs, which the GOP reform would restore. Yet, it estimates a reduction in ...
(Date:3/24/2017)... ... March 24, 2017 , ... Shamanic healer and ... Shamanic Healing and Spiritual Awakening, proudly presents her Sacred Peru retreat with ... sacred and spiritual journey during the Summer Solstice will also be her final ...
(Date:3/24/2017)... ... 2017 , ... On June 9, 2017, Cassie Springer Ayeni ... in Chicago, Illinois. She will present on: , Filing Benefit Claims—Responding to ... involve claims for long-term disability benefits. This session will address the first ...
(Date:3/24/2017)... Texas (PRWEB) , ... March 24, 2017 , ... ... 2017 the year of enhancements, upgrading their training and leads programs. , In ... University. Reserved for elite sales agents, Performance Partners is designed to teach how ...
Breaking Medicine News(10 mins):
(Date:3/27/2017)...  PhaseRx, Inc. (NASDAQ: PZRX), a biopharmaceutical company ... in children, today reported financial results for the ... 2016 and provided an update on its corporate ... progress during the fourth quarter of 2016 through ... safety study, and with our lead development candidate, ...
(Date:3/24/2017)... PUNE, India , March 24, 2017 Abdominal ... to reach $2,614 million by 2022, Globally, registering a CAGR of 5.1% from 2016 ... revenue, and is projected to dominate the market during the study period. ... ... Logo ...
(Date:3/24/2017)... 24, 2017 Research and Markets has ... U.S.: Consumer Strategies" report to their offering. ... Pain Management ... and treat their physical pain, emphasizing consumer survey analysis, including ... sufferers and adults who have selected illnesses/conditions strongly associated with ...
Breaking Medicine Technology: