Navigation Links
Protein Found to Be Essential For Maintaining Nerve Health

A team of researchers led by Michael Kiebler at the Max Planck Institute for Developmental Biology in Tübingen (now at the Center for Brain Research, University of Vienna), have been able to identify a // protein that seems to play a vital role in maintaining the overall health of the nerve cell.

The protein called Staufen2, appears to play a key role in the maintenance of synapses. The researchers found that if this protein was blocked out from a nerve cell, it lost a number of synapses. Synapses are the impulses that connect one nerve cell to the other and thus transmit information through various nerve cells. In the current study, appearing in the January 17 issue of the Journal of Cell Biology, researchers tried to analyze the effect of the loss of Staufen proteins from a nerve cell. These proteins are thought to be involved in transport of molecular blueprints (mRNAs) to specific locations in the cell. Nerve cells transmit information through highly specialized contact sites called as synapses. Proteins are very necessary for the maintenance of these synapses. But protein synthesis at a synapse is possible only when the mRNAs carrying the 'blueprint' arrive at the location. Staufen2 protein has been found to play a key role in this transportation process. Researchers Bernhard Goetze and Paolo Macchi have proved for the first time that Staufen2 is important for the maintenance of synapses. We wanted to know if Staufen2-deficient nerve cells can still transmit signals, said Michael Kiebler. Researchers also teamed up with Stefan Boehms group at the Medical University of Viennas Institute of Pharmacology. This particular research throws light on the intricate mechanisms involved in the brain's ability to learn and to memorize information.

Original work: Goetze B, Tuebing F, Xie Y, Dorostkar MM, Thomas S, Pehl U, Boehm S, Macchi P, and Kiebler MA The brain-specific double-stranded RNA binding protein Staufen2 is required for dendritic spi ne morphogenesis. Journal of Cell Biology, Vol. 172 (2), 17 January 2006

Contact Dr. Michael Kiebler Michael.Kiebler@meduniwien.ac.at Max-Planck-Gesellschaft http://www.mpg.de
'"/>




Related medicine news :

1. Lean Protein Could Be Key to Obesity Drugs
2. Evidence Links Protein Damage to Neurodegenerative diseases like Parkinsons and Alzheimers
3. Unravelling the secrets of ‘Huntingtin’ Protein - towards the treatment of ‘Huntingtons’ Disase
4. Unravelling the secrets of ‘Huntingtin’ Protein - towards the treatment of Huntingtins’ Disese
5. Protein in urine foresees heart disease
6. Levels Of Blood Proteins May Help Heart Disease Care
7. Protein signals need for heart surgery
8. Protein and fat improve memory
9. Clotting Protein plays a role in nerve repair
10. High Levels of Protein Linked to Brain Shrinkage
11. Protein can change worn muscle fibres
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/23/2017)... The Woodlands, Texas (PRWEB) , ... August 23, 2017 , ... ... the leading denied claims firms in Texas. Founded by Bill Voss, the firm grew ... over a decade and a half of helping clients get the money they deserve ...
(Date:8/23/2017)... (PRWEB) , ... August 23, 2017 , ... Drs. Steven ... whitening in Cornelius, NC. By taking advantage of this offer, valued at more ... every regular six-month hygiene cleaning from the dentist, patients receive a complimentary professional whitening ...
(Date:8/23/2017)... (PRWEB) , ... August 23, 2017 , ... ... Therapy continues to prove the safety and efficacy of HBOT in treating and ... across the US, points to research showing the similarities of the wounds to ...
(Date:8/23/2017)... , ... August 23, 2017 , ... The Stevie® Awards have announced the winners of ... , the world’s premier business awards competition. , Nominees in the 2017 IBAs were not ... a points system based on the total number of awards won in the IBAs with ...
(Date:8/23/2017)... (PRWEB) , ... August 23, 2017 , ... ... the healthcare industry, made the 2017 Inc. 5000 with a three-year sales ... the nation’s fastest-growing private companies and comprises the most comprehensive look at America’s ...
Breaking Medicine News(10 mins):
(Date:8/14/2017)... PETACH TIKVAH, Israel , Aug. 15, ... leading developer of adult stem cell technologies for neurodegenerative ... June 30, 2017. ... our pivotal Phase 3 trial to investigate NurOwn ® ... and Chief Executive Officer of BrainStorm. "We have agreements ...
(Date:8/8/2017)...   Second-quarter 2017 revenues of ... share from continuing operations ... to $110 million Second-quarter ... million Second-quarter 2017 adjusted ... 8 percent to $0.93 ...
(Date:8/7/2017)... Inc. (NYSE: DPLO), the nation,s largest independent specialty pharmacy, announced ... comparisons, unless otherwise noted, are to the quarter ended June ... Quarter 2017 Highlights include: Revenue of ... Total prescriptions dispensed of 220,000, compared to ... Gross profit per prescription dispensed of ...
Breaking Medicine Technology: