Navigation Links
Protein Found to Be Essential For Maintaining Nerve Health

A team of researchers led by Michael Kiebler at the Max Planck Institute for Developmental Biology in Tübingen (now at the Center for Brain Research, University of Vienna), have been able to identify a // protein that seems to play a vital role in maintaining the overall health of the nerve cell.

The protein called Staufen2, appears to play a key role in the maintenance of synapses. The researchers found that if this protein was blocked out from a nerve cell, it lost a number of synapses. Synapses are the impulses that connect one nerve cell to the other and thus transmit information through various nerve cells. In the current study, appearing in the January 17 issue of the Journal of Cell Biology, researchers tried to analyze the effect of the loss of Staufen proteins from a nerve cell. These proteins are thought to be involved in transport of molecular blueprints (mRNAs) to specific locations in the cell. Nerve cells transmit information through highly specialized contact sites called as synapses. Proteins are very necessary for the maintenance of these synapses. But protein synthesis at a synapse is possible only when the mRNAs carrying the 'blueprint' arrive at the location. Staufen2 protein has been found to play a key role in this transportation process. Researchers Bernhard Goetze and Paolo Macchi have proved for the first time that Staufen2 is important for the maintenance of synapses. We wanted to know if Staufen2-deficient nerve cells can still transmit signals, said Michael Kiebler. Researchers also teamed up with Stefan Boehms group at the Medical University of Viennas Institute of Pharmacology. This particular research throws light on the intricate mechanisms involved in the brain's ability to learn and to memorize information.

Original work: Goetze B, Tuebing F, Xie Y, Dorostkar MM, Thomas S, Pehl U, Boehm S, Macchi P, and Kiebler MA The brain-specific double-stranded RNA binding protein Staufen2 is required for dendritic spi ne morphogenesis. Journal of Cell Biology, Vol. 172 (2), 17 January 2006

Contact Dr. Michael Kiebler Max-Planck-Gesellschaft

Related medicine news :

1. Lean Protein Could Be Key to Obesity Drugs
2. Evidence Links Protein Damage to Neurodegenerative diseases like Parkinsons and Alzheimers
3. Unravelling the secrets of ‘Huntingtin’ Protein - towards the treatment of ‘Huntingtons’ Disase
4. Unravelling the secrets of ‘Huntingtin’ Protein - towards the treatment of Huntingtins’ Disese
5. Protein in urine foresees heart disease
6. Levels Of Blood Proteins May Help Heart Disease Care
7. Protein signals need for heart surgery
8. Protein and fat improve memory
9. Clotting Protein plays a role in nerve repair
10. High Levels of Protein Linked to Brain Shrinkage
11. Protein can change worn muscle fibres
Post Your Comments:

(Date:6/25/2016)... Long Beach, CA (PRWEB) , ... June 25, 2016 , ... ... from UCLA with Magna Cum Laude and his M.D from the David Geffen School ... San Diego and returned to Los Angeles to complete his fellowship in hematology/oncology at ...
(Date:6/25/2016)... ... ... On Friday, June 10, Van Mitchell, Secretary of the Maryland Department of ... recognition of their exemplary accomplishments in worksite health promotion. , The Wellness at Work ... Symposium at the BWI Marriott in Linthicum Heights. iHire was one of 42 businesses ...
(Date:6/24/2016)... ... 2016 , ... A recent article published June 14 on E ... goes on to state that individuals are now more comfortable seeking to undergo not ... as calf and cheek reduction. The Los Angeles area medical group, Beverly Hills Physicians ...
(Date:6/24/2016)... Marne, Michigan (PRWEB) , ... June 24, 2016 , ... ... awareness about the dangers associated with chronic pain and the benefits of holistic treatments, ... for individuals who are suffering with Sickle Cell Disease. , Sickle Cell Disease (SCD) ...
(Date:6/24/2016)... ... 24, 2016 , ... The Pulmonary Hypertension Association (PHA) learned ... receive two significant new grants to support its work to advance research and ... by recognizing patients, medical professionals and scientists for their work in fighting pulmonary ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... 2016  Arkis BioSciences, a leading innovator in ... durable cerebrospinal fluid treatments, today announced it has ... is led by Innova Memphis, followed by Angel ... investors.  Arkis, new financing will accelerate the commercialization ... release of its in-licensed Endexo® technology. ...
(Date:6/23/2016)... , June 23, 2016 Research ... "Pharmaceutical Excipients Market by Type (Organic Chemical (Sugar, Petrochemical, ... (Oral, Topical, Coating, Parenteral) - Global Forecast to 2021" ... The global pharmaceutical excipients market is ... a CAGR of 6.1% in the forecast period 2016 ...
(Date:6/23/2016)... Capricor Therapeutics, Inc. ... company focused on the discovery, development and commercialization ... in its ongoing randomized HOPE-Duchenne clinical trial (Halt ... its 24-patient target. Capricor expects the trial to ... 2016, and to report top line data from ...
Breaking Medicine Technology: