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Protein Expression to Serve as Marker for Head and Neck Cancer

be from the cancer cells or from the body’s response to cancer,’ she says.

If they are the same, the proteins also could yield novel therapeutic agents, Dr. Adam says.

This will help solidify the link between the protein patterns and cancer as well. ‘For screening you really have to use body fluids: blood, saliva, urine,’ says Dr. Adam. ‘When the normal cell transforms to a cancer cell, we want to see the changes within the cells. When we find the protein differences between cancer cells and normal cells, we can use this information to detect head and neck cancer.’

Interestingly, to date they have not found any proteins expressed by cancer that are not expressed normally; the difference is a matter of degrees of expression, says Dr. Adam, who also is using proteomics to find a better biomarker than prostate specific antigen, or PSA, for prostate cancer.
Source: Eurekalert
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