Stroke patients who take two common blood pressure medications are less likely to suffer dementia or cognitive decline if they have another stroke, finds a new study in this month’s Archives of Internal Medicine.
Dementia is a major health concern in developed nations, ranking as the eighth leading cause of death and disability. Studies have shown elevated blood pressure levels and prior incidence of stroke put people// at especially high risk for these mind-robbing conditions, but doctors are unsure whether treatment of high blood pressure can reduce the risk. Three large studies offered conflicting results: One suggested blood pressure treatment could reduce the risk for dementia but not cognitive decline, a second came out with the opposite finding, and a third showed a beneficial effect but included only a small number of dementia cases.
These researchers conducted a randomized, double-blind, placebo-controlled trial involving around 6,100 people with prior stroke or mini-stroke. About half the group received an ACE inhibitor, a blood pressure drug, and some also received a diuretic. The other half received a placebo. Participants were followed for around four years.
Results showed no clear-cut effect of the active treatment on the overall risk of dementia, but the risk of developing dementia with recurrent stroke was lowered by about a third in those who took the blood pressure medications. The overall risk of developing cognitive decline decreased by about a fifth in the treated group, and the risk of developing cognitive decline with recurrent stroke dropped by a half.
The investigators believe these findings support recommendations calling for all stroke patients to receive treatment with blood pressure lowering drugs.
SOURCE: Archives of Internal Medicine, 2003;163:1069-1075
Page: 1 Related medicine news :1
. Protection mechanism of fatty acids for Cancer2
. Flu Shots Best for Protection3
. Circumcision More Effective In Reducing The Risk Of HIV Protection4
. Diet Found To Offer Protection Against Leukemia5
. New Cost Effective Approach To Promote Sun Protection6
. New Flu Vaccine Can Give Lifetime Protection7
. Sunscreen Lotions Offering High Protection May Be Better Than Usual Sunscreens8
. Protection against Alzheimer’s could be as simple as drinking green te9
. BCG vaccine for both Protection and treatment of Tuberculosis10
. Vegetables And Garlic Confer Protection From Skin Cancer11
. Chromosome Ends Trigger DNA Damage Response For Telomere Protection