Navigation Links
Prostate Cancer in Obese Men

Two new studies show obese men with prostate cancer are at a higher risk of developing more aggressive tumors and of experiencing cancer recurrence than men of normal weight.//

The first study conducted by researchers at the Naval Medical Center in San Diego sampled nearly 3,200 prostate cancer patients. In this group, 19 percent of the patients were considered obese -- defined as having a body mass index higher than 30.

Researchers found a correlation between obesity and a higher Gleason score, the value used to classify the aggressiveness of prostate tumors. They also found obese men tended to have a higher cancer recurrence rate.

The second study was conducted by researchers at Johns Hopkins University School of Medicine on nearly 1,100 prostate cancer patients, 22 percent of who were obese. In this study, obesity was defined as a body mass index higher than 35. As in the first study, researchers concluded that obese men also were more like to have a higher Gleason score. Another similar conclusion was that in both studies black men were more likely to be obese.

Stephen J. Freedland, M.D., co-author of the study, says, "We suspect that worse outcomes among African-American men with prostate cancer are related to obesity rather than race."

Researchers for both studies suggest that proteins and hormones stored in body fat -- such as leptin and insulin-like growth factor 1 -- may encourage prostate tumor growth in obese men. Also, obese men usually have lower testosterone levels and higher estrogen levels, which may promote cancer growth. In addition, diets high in fat may promote tumor growth.

Medical peers agree with the conclusions of the studies and encourage further investigation. Alfred I. Neugut, M.D., Ph. D., of Columbia University, says, "The number of prostate cancer survivors is steadily increasing, and it will be important to investigate if weight loss and other lifestyle changes can impr ove prognosis in those already diagnosed with prostate cancer."


'"/>




Related medicine news :

1. Cancer Doctors Okays Controversial Prostate Therapy
2. Radioactive Seeds used in Prostate Cancer treatment can migrate with the body
3. New Prostate Cancer Vaccine Shows Promise
4. Hormone Therapy applicable for Prostate Cancer
5. Prostate cancer and Vitamins
6. Response to chemotherapy could be measured by Prostate-Specific Antigen Doubling Time
7. Early Detection Of Prostate Cancer
8. Awareness increase Prostate cancer detection
9. Better Prostate Cancer Test
10. Stopping Prostate Cancer from Spreading
11. Drug might prevent Prostate Cancer Spread
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/11/2016)... ... February 11, 2016 , ... ... nominations seeking candidates for the Board of Commissioners. Individuals interested in volunteer board ... experience with diversity of clinical practice settings and across allied health to contribute ...
(Date:2/11/2016)... ... February 11, 2016 , ... PharmMD CEO Robert ... will focus on contract negotiations, corporate strategy and healthcare data law. Additional responsibilities ... practices in data breaches for the Part D Star Rating improvement and Medication ...
(Date:2/11/2016)... ... February 11, 2016 , ... ... master charity program created to assist the people of their local community. The ... nonprofit organizations and community leaders. Their hope is to bring awareness to important ...
(Date:2/11/2016)... ... February 11, 2016 , ... ... hallmark resource, Infusion Therapy Standards of Practice, to include vascular visualization as a ... an estimated 85% share of the market, facilitates adherence to this standard with ...
(Date:2/11/2016)... ... February 11, 2016 , ... Duterte Insurance ... involvement program, introduces a new charity campaign to raise funds for Ronald McDonald ... accepted at https://donate.rmhc.org/ . , Ronald McDonald House (RMH) is an internationally ...
Breaking Medicine News(10 mins):
(Date:2/11/2016)... -- The primary goal of this research is to ... usage of liquid biopsy. Key information the survey seeks ... of liquid biopsy adoption amidst future users - Predominantly ... - Sample inflow to conduct liquid biopsy tests - ... so on. - Correlation analysis of sample type and ...
(Date:2/11/2016)... Feb. 11, 2016  Walgreens has committed to provide ... and Washington, D.C. as part of ... was commended by shareholder advocacy organization As You Sow. ... Sow. "Many people hold on to unneeded drugs because they ... tragic consequences." --> Conrad MacKerron , Senior ...
(Date:2/11/2016)...  MiMedx Group, Inc. (NASDAQ: MDXG ), the ... other birth tissues, human skin and bone, and patent-protected ... products and therapies, announced today that it will present ... in New York , NY.  Parker ... Senken , Chief Financial Officer and Chris Cashman ...
Breaking Medicine Technology: