cipal investigator for the Centinela Freeman ULAAC project.
“This data collection project is being undertaken because very little is known about what causes some individuals to develop cancer while others don’t,” said David B. Agus, M.D., research director for the Louis Warschaw Prostate Cancer Center and co-principal investigator on the project with Ronald Shazer, M.D.
“Once we better understand the genetic and proteomic patterns of men with prostate cancer, we hope to be able to develop more targeted, more individualized – and ultimately, more effective -- treatments for prostate and other cancers,” Dr. Agus said.
Participants must be at least 18 years of age and have prostate cancer and/or prostate disease. For the project, participants will be asked to give approximately four tablespoons of blood during routine blood work. Participants also will be asked to allow tissue removed in any surgeries that would otherwise be discarded to be stored in the repository for future research purposes. This tissue is taken during a scheduled surgery or from a stored sample from a prior surgery; no additional tissue will be removed solely for research purposes. Participants also provide their medical histories and fill out questionnaires. Spouses/significant others that agree to participate will give blood and fill out a questionnaire. If they have been diagnosed with cancer and have a stored tissue sample from a prior surgery, they can give permission to access these samples.
“Participating in this data collection study will not impact any treatment the prostate cancer patients are currently undergoing,” said Dr. Agus. “Rather, it will be used in laboratory settings for studies that will determine cellular growth characteristics of cancer cells, gene and protein expression, and help researchers develop more effective treatment approaches to fighting – and perhaps curing – cancer in the future.”
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