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Premature Vascular and Bone Changes Occur in COPD Patients

ation, the higher the pulse wave velocity values, wrote Drs. Vogelmeier and Bals. Thus, COPD may induce arterial stiffness, which in turn may promote vascular remodeling, thickening of arterial walls and plaque formation. The process may start in the early stages of COPD and worsen with the decline of lung function.

The editorialists also commented on osteoporosis, which was the second focus of the study: The authors found that bone mineral density was lower in patients with COPD than in control subjects. Among the patients with COPD, 32 percent had osteoporosis and this was not restricted to those with severe COPD.

Although the editorialists termed the relationship between COPD and osteoporosis in the study was not novel, they noted that those patients with osteoporosis also had the greatest arterial stiffness valuesa new finding.

They concluded that future research is necessary to uncover further relationships between this studys findings and accelerated aging processes in COPD, which might then be avoided.


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