Navigation Links
Predicting Breast Cancer Recurrence By Understanding Gene Signature

Researchers say they have now identified a group of genes known as a gene signature, that could help single out which breast cancer patients may be at high risk for having a future cancer recurrence .//

For the study the gene expressions in 286 tumor samples from 209 lymph-node-negative breast cancer patients were examined. The patients had not received hormone or chemotherapy after their initial cancer treatment and varied in age and in their tumor sizes.

Results analyzed, after a follow-up averaging eight years, showed 93 of the women had cancer that spread to another part of their body. Through analyzing 115 of the tumors, researchers identified a 76-gene signature that could predict cancer relapse. The gene signature was tested on 171 lymph-node-negative patients in the study and it predicted (with a 93-percent sensitivity) which patients would have a cancer recurrence within five years. However the test was less accurate (with a 46-percent sensitivity) at predicting cancer recurrence beyond five years.

Since some studies identifying gene signatures for breast cancer recurrence do not identify the same groups of genes when compared, researchers say it becomes difficult to determine which gene signature test to trust. Thus in conclusion researchers say if further studies are done it could help determine better treatment plans for cancer patients .

Page: 1

Related medicine news :

1. Predicting The Risk Of Preeclampsia During Pregnancy
2. Predicting The Risk Of A Heart Attack
3. Predicting Severity Of Appendicitis With Computed Tomography
4. Predicting The Risk Of Breast Cancer In The Future
5. Predicting The Risk Of Osteoarthritis
6. Researchers Find Mix of Biomarkers Predicting Mortality
7. Biomarkers Predicting Mortality Found Using Statistical Technique
8. HIV RNA Level Seen As Little Value In Predicting Treatment
9. Predicting the Dynamics of Clotting in Human Blood
10. Follicle Count Test as Good as Hormone Tests in Predicting Ovarian Response
11. Consensus on "Combination Therapy" for Breast Cancer
Post Your Comments:

(Date:6/26/2016)... ... 27, 2016 , ... Quality metrics are proliferating in cancer care, and are ... the eye of the beholder, according to experts who offered insights and commentary in ... Managed Care. For the full issue, click here . , For the American ...
(Date:6/26/2016)... Clarkston, Michigan (PRWEB) , ... June 26, 2016 ... ... respect to fertility once they have been diagnosed with endometriosis. These women need ... but they also require a comprehensive approach that can help for preservation of ...
(Date:6/25/2016)... ... June 25, 2016 , ... First Choice Emergency ... named Dr. Sesan Ogunleye, as the Medical Director of its new Mesquite-Samuell Farm facility. ... Director of our new Mesquite location,” said Dr. James M. Muzzarelli, Executive Medical Director ...
(Date:6/24/2016)... ... June 24, 2016 , ... A recent article ... people are unfamiliar with. The article goes on to state that individuals are now ... of these less common operations such as calf and cheek reduction. The Los Angeles ...
(Date:6/24/2016)... ... ... Global law firm Greenberg Traurig, P.A. announced that 20 Florida attorneys are recognized ... this recognition are considered among the top 2 percent of lawyers practicing within the ... this year’s Legal Elite Hall of Fame: Miami Shareholders Mark D. Bloom, Burt ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... , June 23, 2016 Revolutionary ... Oticon , industry leaders in advanced audiology ... of Oticon Opn ™, the world,s first internet ... possibilities for IoT devices.      (Photo: ... introduces a number of ,world firsts,: , ...
(Date:6/23/2016)... 2016 The vast majority of dialysis patients ... Treatments are usually 3 times a week, with treatment ... travel time, equipment preparation and wait time.  This regimen ... for patients who are elderly and frail.  Many elderly ... rehabilitation centers for some duration of time. ...
(Date:6/23/2016)... , June 23, 2016  Experian Health, ... and transforming the patient payment and care ... innovative new products and services that will ... revenue cycle offerings. These award-winning solutions will ... workflows, remain compliant in an ever-changing environment ...
Breaking Medicine Technology: