Navigation Links
Potential New Cancer Gene Identified

A Johns Hopkins University research team has discovered a new family of genes that contributes to the process of malignancy, shedding new light on the abnormalities that give rise to the aggressive childhood cancer, Burkitt's lymphoma - as well as lymphoma, leukemia, prostate, ovarian, lung, and breast cancer.

Characterized by rapidly growing abdominal tumors, Burkitt's lymphoma is one of the three major types of pediatric non-Hodgkin's lymphomas, representing 40% of that group. According to the American Cancer Society, aproximately 57,000 children are diagnosed with non-Hodgkin's lymphoma per year in the United States, representing about 6% of cancers in children. While aggressive, Burkitt's lymphoma responds well to chemotherapy, and has a 90% survival rate if the tumor has not spread beyond the abdomen.

Scientists have long known that the "myc" family of genes plays a prominent role in tumor formation, also called neoplastic transformation. The Hopkins team, focusing on c-myc, found that another gene called the HMG-I/Y gene is a key genetic "target" necessary for Myc-mediated transformation.

When the expression of this target gene in Burkitt's lymphoma cell lines was blocked, the cancer cells revert back to normal-appearing cells. This could point the way to new therapies for one of the most aggressive childhood cancers, as well as other cancers associated with increases in the HMG-I/Y gene according to the Johns Hopkin's research team.
'"/>




Page: 1

Related medicine news :

1. Lack of Smell And Its Potential Risks
2. New Blood Thinner Pill - First Potential Alternative to Warfarin in 50 years
3. The Potential Of Cadaver Transplantation Programme In India
4. Another Potential Of Stem Cells Discovered: Used For Growing Cartilage
5. Yoga Guru Ramdev Invited to Tap Ayurveda Potential by Jharkhand Govt
6. A Protein In Yoghurt Has The Potential To Fight E. coli
7. Gold Therapy- A Potential Treatment For Autoimmune Diseases
8. Whirlpool Bath Tubs Contain Potentially Lethal Bacterial Strains
9. Potential Benefits Of New Nanotechnology
10. Hormone Can Foretell Presence Of Potentially Fatal Pulmonary Hypertension
11. UC Researchers Find Potential Drug Target For SARS
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/21/2017)... , ... April 21, 2017 , ... ... it’s been named Agency of Record (AOR) for Theravent, Inc. , the ... snoring. Theravent’s parent company, Foundation Consumer Healthcare, is now working to expand distribution ...
(Date:4/21/2017)... ... April 21, 2017 , ... Crossover ... O2X , an active lifestyle company that provides Human Performance Training and ... firefighters, police offers, first responders, military officers and others in service through the ...
(Date:4/21/2017)... , ... April 21, 2017 , ... Alive for ... who wish to overcome their mental health struggles. The Alive team uses advanced ... says: “Our approach in dealing with a mental health struggle is based on ...
(Date:4/21/2017)... ... 21, 2017 , ... Northern California Medical Associates ... Symposium on April 1, 2017 in Santa Rosa. This well-attended annual conference plays ... an opportunity to learn about cutting edge treatments, to collaborate, share research and ...
(Date:4/21/2017)... ... April 21, 2017 , ... ... practices, is seeking candidates to serve on its Accreditation and Standards Committees ... “RadSite’s ultimate mission is improving image quality and reducing patient radiation dose,” ...
Breaking Medicine News(10 mins):
(Date:4/20/2017)... 20, 2017  AbbVie (NYSE: ABBV), a global ... of chronic hepatitis C virus (HCV) infected patients ... and compensated cirrhosis (Child-Pugh A) achieved sustained virologic ... with its investigational, pan-genotypic regimen of glecaprevir/pibrentasvir (G/P). ... following 12 weeks of G/P treatment without ribavirin. ...
(Date:4/19/2017)... Medical Corporation (TSX: CRH) (NYSE MKT: CRHM) (the "Company"), announces that it ... 2017 at the Sheraton Hotel in Toronto, Ontario ... the Company is scheduled to present on Tuesday, May 2 at ... Chairman of the Board, Tony Holler will also attend ... For more details ...
(Date:4/19/2017)... April 19, 2017 Global Prostate Cancer ... on the prostate cancer therapeutics market analyzes the ... Increasing prevalence of prostate cancer, launch of promising ... development of new drugs & therapeutic biological products, ... due to lesser side effects are some of ...
Breaking Medicine Technology: