Navigation Links
Possible Viral Cause Of Kawasaki Disease Identified

In what can be stated as a breakthrough in infectious disease research, scientists have identified a possible viral cause of Kawasaki disease, the most common cause of acquired heart disease in children in developed nations. //

Their study findings appear in the November 15 issue of the Journal of Infectious Disease.

An infectious cause for the disease has been suspected since 1967, when Kawasaki disease was originally described, but, until now, none has been identified.

The research group was led by Anne H. Rowley, professor of pediatrics and of microbiology/immunology at Northwestern University Feinberg School of Medicine and Children's Memorial Hospital.

In previous research, Rowley and colleagues showed that synthetic versions of immunoglobulin A antibodies made by children who developed Kawasaki disease bind, or attach, to spheroid structures in the bronchi, the breathing tubes in the lung. These antibodies are likely produced to combat the infectious cause of the disease.

In the current study, Rowley and co-investigators examined the spheroid structures in acute Kawasaki disease bronchi closely, using a variety of microscopic stains including the very high-powered electron microscope.

The researchers determined that the spheroid structures are inclusion bodies consisting of proteins and nucleic acids, characteristic of an infectious agent such as a virus.

Findings from the study suggest a single respiratory viral cause or closely related viral mediators as causing Kawasaki disease, entering through the respiratory route, infecting bronchi and leading to the formation of inclusion bodies in the bronchi of children with the disease.

'The virus is likely to be taken up by white blood cells in the lung and carried through the bloodstream, infecting other tissues, including the coronary artery, and leading to coronary artery aneurysms, the most important adverse outcome of Kawasaki disease,' Rowley said.

Results of the study provide new insights into the cause and disease course of acute Kawasaki disease, and suggest new directions for homing in on the cause of the disease.

This study was supported by grants from the National Institutes of Health and the Kawasaki Disease Research Fund of Children's Memorial Hospital.
'"/>




Related medicine news :

1. Life Saving Cancer Drugs – From Chicken! Possible Says Dolly’ Creatos
2. Possible benefits of Hormone Replacement Therapy
3. Low Protein Levels A Possible Indicator For A Miscarriage
4. Cure For Persistent Oral Fungal Problem May Be Possible
5. Transfer Of Rabies Virus Possible From Organ Donor To Recipient
6. Possible location of lung cancer genes found
7. Treatment May Be Possible For Degenerative Brain And Spinal Cord Disease
8. Its Possible To Grow Bone To Replace The Damaged Bone
9. Healthy At 50: Possible?
10. Outpatient Treatment Possible For Patients with Uterine Fibroid Tumors
11. Safe Driving Is Possible For Older People If They Are Prepared
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/29/2017)... ... April 29, 2017 , ... TransDark is a set ... one video to the next without having to set a single keyframe in ... to enhance your video production. , TransDark features dynamic transitions that momentarily splits the ...
(Date:4/28/2017)... (PRWEB) , ... April 28, 2017 , ... An April 24th article on ... stunning 180 pounds with the help of a weight loss surgery. The woman, declaring “I ... skin that have been left following her dramatic weight loss. Dr. Feiz & Associates notes ...
(Date:4/28/2017)... , ... April 28, 2017 , ... Beginning in 2017, ... their formulas. This begins with the popular ClearLungs Extra Strength formula. To ensure that ... the formula in the following ways:, , Removal of the ...
(Date:4/28/2017)... ... April 28, 2017 , ... Ushio America ... lamps offer an instant energy-saving solution for F32T8 fluorescent lamps on most instant-start ... ballasts. These 50,000 hour rated lamps utilize the existing electronic ballast, saving labor ...
(Date:4/28/2017)... ... April 28, 2017 , ... From ... College of Urgent Care Medicine will host industry leaders for the annual spring ... help those in the industry adapt to the issues currently affecting urgent care ...
Breaking Medicine News(10 mins):
(Date:4/20/2017)... 20, 2017  Cogentix Medical, Inc. (NASDAQ: CGNT), ... the Urology, Uro/Gyn and Gynecology markets with innovative ... has joined the Company as Senior Vice President, ... position, Mr. Keswani will report directly to ... "Our organization is delighted that Ash has joined ...
(Date:4/20/2017)... , April 20, 2017  RXi Pharmaceuticals Corporation ... therapeutics that address significant unmet medical needs, today ... the Company,s consumer product development program, based on ... Society for Investigative Dermatology (SID) 76 th ... and promote the sciences relevant to skin health ...
(Date:4/20/2017)... , April 20, 2017  AbbVie (NYSE: ... 99 percent (n=145/146) of chronic hepatitis C virus ... 5 or 6 and compensated cirrhosis (Child-Pugh A) ... (SVR 12 ) with its investigational, pan-genotypic regimen ... rates were seen following 12 weeks of G/P ...
Breaking Medicine Technology: