Navigation Links
Possible Viral Cause Of Kawasaki Disease Identified

In what can be stated as a breakthrough in infectious disease research, scientists have identified a possible viral cause of Kawasaki disease, the most common cause of acquired heart disease in children in developed nations. //

Their study findings appear in the November 15 issue of the Journal of Infectious Disease.

An infectious cause for the disease has been suspected since 1967, when Kawasaki disease was originally described, but, until now, none has been identified.

The research group was led by Anne H. Rowley, professor of pediatrics and of microbiology/immunology at Northwestern University Feinberg School of Medicine and Children's Memorial Hospital.

In previous research, Rowley and colleagues showed that synthetic versions of immunoglobulin A antibodies made by children who developed Kawasaki disease bind, or attach, to spheroid structures in the bronchi, the breathing tubes in the lung. These antibodies are likely produced to combat the infectious cause of the disease.

In the current study, Rowley and co-investigators examined the spheroid structures in acute Kawasaki disease bronchi closely, using a variety of microscopic stains including the very high-powered electron microscope.

The researchers determined that the spheroid structures are inclusion bodies consisting of proteins and nucleic acids, characteristic of an infectious agent such as a virus.

Findings from the study suggest a single respiratory viral cause or closely related viral mediators as causing Kawasaki disease, entering through the respiratory route, infecting bronchi and leading to the formation of inclusion bodies in the bronchi of children with the disease.

'The virus is likely to be taken up by white blood cells in the lung and carried through the bloodstream, infecting other tissues, including the coronary artery, and leading to coronary artery aneurysms, the most important adverse outcome of Kawasaki disease,' Rowley said.

Results of the study provide new insights into the cause and disease course of acute Kawasaki disease, and suggest new directions for homing in on the cause of the disease.

This study was supported by grants from the National Institutes of Health and the Kawasaki Disease Research Fund of Children's Memorial Hospital.
'"/>




Related medicine news :

1. Life Saving Cancer Drugs – From Chicken! Possible Says Dolly’ Creatos
2. Possible benefits of Hormone Replacement Therapy
3. Low Protein Levels A Possible Indicator For A Miscarriage
4. Cure For Persistent Oral Fungal Problem May Be Possible
5. Transfer Of Rabies Virus Possible From Organ Donor To Recipient
6. Possible location of lung cancer genes found
7. Treatment May Be Possible For Degenerative Brain And Spinal Cord Disease
8. Its Possible To Grow Bone To Replace The Damaged Bone
9. Healthy At 50: Possible?
10. Outpatient Treatment Possible For Patients with Uterine Fibroid Tumors
11. Safe Driving Is Possible For Older People If They Are Prepared
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:1/18/2017)... ... January 18, 2017 , ... The VA Maryland ... collaborating on a research project focused on multiple sclerosis (MS). Led by Christopher ... nanotechnology to control the disease without compromising normal immune function that often occurs ...
(Date:1/18/2017)... West Palm Beach, FL (PRWEB) , ... January 18, 2017 , ... ... April as a fund raiser for Smile Train, an international charity that provides free ... is a hobby of mine and in the past I have run to support ...
(Date:1/18/2017)... ... January 18, 2017 , ... At Hallmark Nameplate, their commitment to quality ... achieved certification to ISO 13485. This certification is another way they are making constant ... and services that they need. , The ISO 13485 Certification is a major accomplishment ...
(Date:1/18/2017)... ... January 18, 2017 , ... The Hear the ... project with the donation of cochlear implants. In February 2017, the first three ... a fair chance of leading an independent life. This engagement builds on the ...
(Date:1/17/2017)... , ... January 17, 2017 , ... January is National Stalking Awareness Month ... to lurk in the corners and commit the crime of stalking, a very real danger ... addiction, an often overlooked factor in stalking and other crimes. , “Stalking: know it. Name ...
Breaking Medicine News(10 mins):
(Date:1/18/2017)... , Jan. 18, 2017  Eisai Inc., ... announced today that it is participating in Access ... non-communicable diseases (NCDs) prevention, treatment and care in ... Accelerated is the first multi-stakeholder, international initiative in ... pharmaceutical companies, including Eisai, in collaboration with the ...
(Date:1/18/2017)... NEW YORK , January 18, 2017 ... perception of people regarding the use of cannabis both for ... not only are more Americans open to the use of ... and financial sectors. According to Arcview Market Research, the North ... 2016, up 30% from the previous year. The research projects ...
(Date:1/17/2017)... Jan. 17, 2017 Precision medicine is ... the treatment of disease. The approach allows doctors ... a therapy. The approach studies the individual profile ... and environment. In January 2015, Precision Medicine Initiative ... all diseases with more than one million volunteers. ...
Breaking Medicine Technology: