Navigation Links
Popular Herbal Supplement Hinders the Growth of Pancreatic Cancer Cells

A new study from the University of Pittsburgh Cancer Institute suggests that a commonly used herbal supplement, triphala, has cancer-fighting properties// that prevent or slow the growth of pancreatic cancer tumors implanted in mice. The study found that an extract of triphala, the dried and powdered fruits of three plants, caused pancreatic cancer cells to die through a process called apoptosis – the body’s normal method of disposing of damaged, unwanted or unneeded cells. This process often is faulty in cancer cells. Results of the study, abstract number LB-142, are being presented in a late-breaking session at the annual meeting of the American Association for Cancer Research, April 14-18, at the Los Angeles Convention Center.

Triphala, one of the most popular herbal preparations in the world, is used for the treatment of intestinal-related disorders. It is typically taken with water and thought to promote appetite and digestion and to increase the number of red blood cells.

"We discovered that triphala fed orally to mice with human pancreatic tumors was an extremely effective inhibitor of the cancer process, inducing apoptosis in cancer cells," said Sanjay K. Srivastava, Ph.D., lead investigator and assistant professor, department of pharmacology, University of Pittsburgh School of Medicine. "Triphala triggered the cancerous cells to die off and significantly reduced the size of the tumors without causing any toxic side effects."

Dr. Srivastava and colleagues fed mice grafted with human pancreatic tumors 1 to 2 milligrams of triphala for five days a week and then compared tumor size and levels of apoptotic proteins in the tumors to a control group of mice that received normal saline only. They found that the mice that received triphala had increased levels of proteins associated with apoptosis and significantly smaller tumor sizes when compared to the control group. Triphala-treated tumors were half the size of tumors in untre ated mice. Further testing revealed that triphala activated tumor-suppressor genes, resulting in the generation of proteins that support apoptosis, but did not negatively affect normal pancreatic cells.

"Our results demonstrate that triphala has strong anticancer properties given its ability to induce apoptosis in pancreatic cancer cells without damaging normal pancreatic cells," said Dr. Srivastava. "With follow-up studies, we hope to demonstrate its potential use as a novel agent for the prevention and treatment of pancreatic cancer," said Dr. Srivastava.

Source-Eurekalert/
'"/>




Related medicine news :

1. Uterine Fibroid Embolization Gaining Popularity
2. Study Warns About The Use Of Popular Asthma Drug To Stop Childrens Coughs
3. Popularity Of Homeopathy On The Increase
4. Popularity Among Peers Increases Susceptibility To Smoking Habit Among School Children
5. Valentine Day Becoming Popular In India
6. Bio-functional Garments Gaining Popularity
7. Warfarin the Not So Popular Drug for Stroke
8. Tooth Enamel Eaten Away By Popular Drinks
9. Chinese NGO To Popularize Sex Education For Youngsters
10. Concerns About Popular Anti-Ulcer Pill Used For Inducing Labor
11. FDA issues warnings on Three Popular Asthma drug labels
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:1/19/2017)... ... January 19, 2017 , ... ... has recently unveiled impressive transportable capabilities with their iMedHD2™ Portable Teleultrasound ... extension to RMT technology that delivers HD, dynamic, streaming ultrasound images and video ...
(Date:1/19/2017)... ... January 19, 2017 , ... Catalent Pharma Solutions, the ... and consumer health products, today announced that it will be co-hosting a workshop ... excipients and drug delivery solutions to health industries worldwide. The one day event ...
(Date:1/19/2017)... ... January 19, 2017 , ... Bio-Optronics Inc. is proud to ... workflow designed to seamlessly integrate and streamline the way researchers prepare and conduct ... maximizing usability and improving efficiency significantly for users – a first in the ...
(Date:1/19/2017)... ... January 19, 2017 , ... ... offering treatments for patients with sleep apnea and TMJ disorders. These conditions are ... physical health. Dr. Rassouli provides personalized care to reduce the risk of these ...
(Date:1/19/2017)... ... ... Allegheny Health Network (AHN) officials today announced a bold new step to greatly ... in the greater Pittsburgh region. Starting January 23, patients who call AHN by 11 ... afternoon. , AHN is the first healthcare provider in the region ...
Breaking Medicine News(10 mins):
(Date:1/19/2017)... January 19, 2017 ... Oncology & Haematology, 2016;12(Suppl 2):3-8; http://www.touchoncology.com/articles/optimising-clinical-outcomes-gastrointestinal-cancers-through-inhibiting-angiogenesis-and ... ... Published recently in a supplement to ... from touchONCOLOGY, an article by James Gilbart ...
(Date:1/19/2017)... , Jan. 19, 2017 ViewRay, Inc. ... a federal institution supporting research in Germany ... and patient treatments at the University Clinic Heidelberg as ... The MRIdian Linac program will be headed by ... also heads radiation oncology at the German Cancer Research ...
(Date:1/19/2017)... Jan. 19, 2017   Science Exchange , the ... announce that the first five replication studies from ... been published in eLife today. Despite intense scrutiny ... first practical evaluation of reproducibility rates that may ... Unlike other assessments of reproducibility, the results of ...
Breaking Medicine Technology: