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Popular Antiaging Supplement Has No Beneficial Effects

e been associated with longevity in humans and nonhuman primates. But studies involving rodents aren’t applicable to humans, as rodents have very low levels of DHEA, the authors say.

The study also involved administering low-dose testosterone to elderly men who had low testosterone. The authors found testosterone offered minimal beneficial effects on bone density, and far less than those offered by many current accepted therapies. Investigators found no negative side effects, although they caution that the study was conducted only in men without prostate problems.

The New England Journal of Medicine published an accompanying editorial to Mayo’s study, with Paul Stewart, M.D., of the University of Birmingham, Ala., saying the search for eternal youth will continue. But in light of the Mayo findings, he suggests DHEA should no longer be accepted as a food supplement and should instead be treated as a regulated drug.

“Appropriate regulation would dispel much of the quackery associated with this elusive hormone,” Dr. Stewart writes.

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