Navigation Links
Pomegranate Juice Is Helpful In Arresting Osteoarthritis

Being one of the fastest progressing and spreading diseases of present time’s arthritis is a menace. Lot of research is going on in this direction and a new study states that pomegranate fruit extracts can block enzymes // that contribute to osteoarthritis.

The study was conducted at Case Western Reserve University School of Medicine. It looked at the ability of an extract of pomegranate fruit against Interleukin-1b (IL-1b), a pro-inflammatory protein molecule that plays a key role in cartilage degradation in osteoarthritis. Current treatments for osteoarthritis – which affects 20 million people nationwide, according to the National Institutes of Health – offer limited effectiveness and do little to slow joint destruction and disease progression.

"Arthritis is one of the foremost diseases for which patients seek herbal or traditional medicine treatments. However, all the extracts and herbs have not yet been scientifically evaluated for their efficacy and safety. Indeed, some of them may even interfere with the current treatments," Haqqi said. "Therefore, careful use of supplements and herbal medicines during early stages of disease or treatment may be made to limit the disease progression."

Pomegranate, in particular, has been found to possess antioxidant and anti-inflammatory properties that have potential therapeutic benefits in a variety of diseases. The Case study demonstrated for the first time the ability of pomegranate fruit extracts to slow the deterioration of human cartilage. A bonus with the native Persian fruit is that its antioxidant constituents are rapidly absorbed by the body and are non-toxic.

Using tissue samples of human cartilage affected by osteoarthritis, researchers added a water extract of pomegranate fruit to the culture using a well-established in vitro model. The findings showed a new activity for pomegranate fruit extract – namely cartilage protection – in addition to its previously discovered a ntioxidant and anti-inflammatory properties.

The IL-1b protein molecules create an overproduction of inflammatory molecules including matrix metalloproteases (MMP), which are tightly regulated enzymes necessary for tissue remodelling. When overproduced in a disease state, such as osteoarthritis, they degrade the cartilage resulting in joint damage and destruction.

The Case study results indicate that pomegranate fruit extracts inhibit the overproduction of MMP enzymes in human cartilage cells.

"This suggests that consumption of pomegranate fruit extract may help in protecting cartilage from the effects of IL-1b by suppressing cartilage degradation in OA," Haqqi said.

Source: Journal of Nutritin.

Related medicine news :

1. Pomegranate Juice May Be The Next Best Thing For People With Heart Disease
2. Pomegranate juice to check fetal brain injury
3. Pomegranate juice delays prostate cancer
4. Pomegranates Found To Slow Prostate Cancer Progression
5. Pomegranate Juice Consumption May Improve Myocardial Ischemia
6. Pomegranates In Snack-Sized Bars
7. Pomegranate Juice Remedy for Prostate Cancer
8. Pomegranate juice could kill cancer cells
9. Pomegranate juice may cut atherosclerosis risk in diabetics
10. Science Builds Behind Pomegranate Extracts for Health
11. Juices are Best! but which one?
Post Your Comments:

(Date:6/24/2016)... ... ... People across the U.S. are sharpening their pencils and honing their writing ... which patients and their families pay tribute to a genetic counselor by nominating him ... Genetic Counselors (NSGC) Annual Education Conference (AEC) this September. , In April, Genome ...
(Date:6/24/2016)... New York, NY (PRWEB) , ... June 24, ... ... lifestyle publication Haute Living, is proud to recognize Dr. Barry M. Weintraub as ... believes that “the most beautiful women in the world, and the most handsome ...
(Date:6/24/2016)... ... June 24, 2016 , ... Strategic Capital Partners, LLC ... by obtaining investment capital for emerging technology companies. SCP has delivered investment ... resulted in more than a million dollars of capital investment for five companies. ...
(Date:6/24/2016)... ... ... Venture Construction Group (VCG) sponsors Luke’s Wings 5th ... Woodmont Country Club at 1201 Rockville Pike, Rockville, Maryland, 20852. The event raised ... have been wounded in battle and their families. Venture Construction Group is a 2016 ...
(Date:6/24/2016)... Gilbert, Arizona (PRWEB) , ... June 24, 2016 ... ... Gilbert-based practice, is supporting the upcoming 2016 Miss Arizona pageant as its official ... primarily serves Scottsdale, Tempe, Mesa, and Chandler, Arizona. , Dr. Olson says ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... Va. , June 24, 2016 The ... set of recommendations that would allow biopharmaceutical ... (HCEI) with entities that make formulary and coverage decisions, ... the "value" of new medicines. The recommendations ... does not appear on the drug label, a prohibition ...
(Date:6/24/2016)... India , June 24, 2016 ... Needles Market by Type (Standard Pen Needles, Safety Pen ... Therapy (Insulin, GLP-1, Growth Hormone), Mode of Purchase (Retail, ... by MarketsandMarkets, This report studies the market for the ... expected to reach USD 2.81 Billion by 2021 from ...
(Date:6/23/2016)...  MedSource announced today that it has selected ... of choice.  This latest decision demonstrates MedSource,s commitment ... clients by offering a state-of-the-art electronic data capture ... as the EDC platform of choice in exchange ... has long been a preferred EDC platform by ...
Breaking Medicine Technology: