Navigation Links
Plavix Safe During and After Heart Bypass

A new study finds the popular anti-clotting drug clopidogrel (Plavix) when taken along with aspirin after off-pump heart bypass surgery, is safe without any adverse bleeding event.//

The study, to be presented at the American College of Cardiology’s 56th Annual Scientific Session on March 27 at 9 am (abstract 1027-18), found that Plavix, when used in addition to aspirin, will not worsen bleeding after off-pump heart bypass surgery.

The researchers led by David Whellan, M.D., assistant professor of Medicine at Jefferson Medical College of Thomas Jefferson University, conducted a retrospective study of more than 7, 000 patients who underwent off-pump heart bypass surgery. They report that the anti-platelet drug program appears safe--post surgery--when used with aspirin. Overall, they found that patients who took clopidogrel and aspirin experienced less gastrointestinal bleeding and fewer strokes and other cardiovascular complications than patients who were on aspirin alone.

"The new off-pump strategy is a proven surgical advance in the treatment of heart disease," Dr. Whellan says. "Improving outcomes for patients undergoing bypass surgery and keeping the new bypass grafts open is a critical issue. One possible strategy is to use clopidogrel, but there have been safety concerns, particularly regarding the risk of bleeding after surgery."

The researchers used data provided by the University HealthSystem Consortium (UHC), an alliance of 97 academic medical centers and 149 of their affiliated hospitals representing nearly 90 percent of the nation’s non-profit academic medical centers. The data were culled from over 800 institutions including more than 70 academic medical centers.

Data were used from patients who underwent off-pump coronary artery bypass surgery, known as OPCABG, and were treated with aspirin alone or with aspirin and clopidogrel. Data on patients who received anticoagulation agents for valve replacemen t and/or atrial fibrillation was excluded. Some 3,512 patients took only aspirin; 3,814 patients were treated with the aspirin and clopidogrel.

"We have learned from our cardiologist colleagues that routine clopidogrel use after angioloplasty and stenting has added a long-term benefit of increased stent effectiveness," adds Scott Silvestry, M.D., assistant professor of Surgery at Jefferson Medical College of Thomas Jefferson University. "This study has shown that we can extend this potential benefit to our off-pump bypass grafts in a safe fashion by utilizing clopidogrel postoperatively without adverse bleeding events."

"The next step will be to evaluate the addition of clopidogrel in a prospective study," Dr. Whellan says.

Source-Eurekalert
PR
'"/>




Related medicine news :

1. Plavix Gets FDA Okay for New Indication
2. Sanofi-Aventis Allows Thais To Make Plavix
3. Oxygen Usage During Exercise Could Indicate Heart Problems
4. Predicting The Risk Of Preeclampsia During Pregnancy
5. Drugs Taken During Pregnancy Found To Affect Unborn Babies
6. Alcohol Consumption During Pregnancy Not Safe
7. The Importance Of “ Good ”Control Of Diabetes During Pregnanc
8. The Effects Of Dental X-Rays During Pregnancy Questioned
9. The Use Of Antioxidants To Diminish Effects of Alcohol During Pregnancy Questioned
10. Oxygen Consumption During Workouts Could Indicate Heart Problems
11. Folic Acid Supplementation During Pregnancy Could Help Prevent Spina Bifida
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/5/2016)... ... February 05, 2016 , ... Dr. ... announces that it is now welcoming orthodontist, Dr. Amanda Cheng, to the practice. ... range of oral health care, including general dentistry, cosmetic treatments, periodontics, implant ...
(Date:2/5/2016)... ... 05, 2016 , ... Health and wellness is a topic that should concern ... they are experiencing an illness. Migraines are a severe form of a headache and ... would not wish the pain on their worst enemy, the feeling can last for ...
(Date:2/5/2016)... Russia (PRWEB) , ... February 05, 2016 , ... Calls ... has a completely new user interface design and the developer has fixed known bugs ... those they want to on their phone while not consuming any of their device’s ...
(Date:2/5/2016)... ... February 05, 2016 , ... Susan Polk Health ... Luis Obispo users can expect to see in 2016. To view the report, see ... changes will directly impact many San Luis Obispo seniors who rely on Medicare health ...
(Date:2/4/2016)... (PRWEB) , ... February 04, 2016 , ... According to ... are advised to see their dentist once every six months for a cleaning and ... visits. , Dr. Farzad Feiz, head dentist at Calabasas Dental Group and California ...
Breaking Medicine News(10 mins):
(Date:2/5/2016)... Feb. 5, 2016  Zimmer Biomet Holdings, Inc. (NYSE ... previously announced underwritten secondary offering of 11,027,558 shares of ... of affiliates of Blackstone and Goldman Sachs.  The shares ... price of $96.45 per share. The selling stockholders will ... Zimmer Biomet nor any of its directors, officers or ...
(Date:2/5/2016)... Site Profile: --> Site ... People, announced their latest primary healthcare case study where speech recognition ... and to save the practice money. Site Profile: ... Challenge: --> ,- Wirral CCG ,- VoicePower client since ... Wirral CCG ,- VoicePower client since 2013 Challenge: ...
(Date:2/4/2016)... 2016 For hospitals considering enrollment in the ... in the program, the Health Resources and Services Administration,s ... , Mega-Guidance , could have significant impact on plans ... September 2016. Essential Insights , Daniel ... summarizes the Mega-Guidance,s key proposed changes, including a new ...
Breaking Medicine Technology: