Navigation Links
Platelets May Be The Source Of Gene Regulations

Researchers from University of Utah School of Medicine had reported that a key process in gene regulation could occur in human platelets. These are unique cells that are unusual because they don’t have a nucleus // (anucleate).

Scientists long have thought the transformation of pre-mRNA into mature mRNA—called splicing—happens only in a cell’s nucleus. But using stem cells from human umbilical cord blood to engineer the precursor cell that forms platelets and platelets isolated from the blood of study subjects, the Utah researchers found that splicing also takes place in the cytoplasm of circulating platelets.

The U researchers, who report their findings in the August edition of the journal Cell, also identified the pre-mRNA in blood platelets that codes for Interleukin 1? (IL-1?), a key protein in an ancient molecular system that plays major roles in inflammation, defense against infection, organ development, and disease. When blood platelets are activated through biochemical signals in response to injury, the IL-1? pre-mRNA is processed into the mature mRNA and then directs production of the critical inflammatory protein.

Finding that platelets can splice the IL-1? pre-mRNA was completely unexpected and emerged while the researchers were engaged in earlier studies of how platelets communicate with certain leukocytes (white blood cells). During that investigation the scientists had found evidence of platelets making new proteins, which led them to pursue the mechanisms that are involved.

Researchers theorize that splicing outside the nucleus is one of a number of intricate ways the body maintains more precise control over gene expression. Many of these control mechanisms are just coming to light.

Source: Newswse
'"/>




Page: 1

Related medicine news :

1. Quality Platelets and Improved Blood Availability No Longer a Pipe Dream
2. Startling Expose – Physicians Often Have No Regular Source Of Health Car
3. Indian Cherry: Richest Source of Vitiamin C
4. Urban Monkeys Source Of Virus Infections
5. Parents – Teen’s Most Reliable Source for Sex Educatin
6. Fruit And Vegetable Peels Are Rich Source Of Potent Antioxidants
7. New York- A haven For the Distressed or a Source of Distress?
8. Results of Clinical Trials Vary According to Source of Funding
9. Source of obesity linked to eating pattern!
10. Mushrooms are Rich Source of Antioxidants
11. Bacteria Killed By Radiation Serves As an Effective Source of Vaccine
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/24/2017)... ... ... Patients who want to receive cosmetic dentistry procedures such as Invisalign® or ... a consultation, with or without a referral. Dr. Bedich enjoys improving the appearance of ... Dr. Bedich offers a variety of cosmetic dentistry services at his practice that are ...
(Date:5/24/2017)... ... ... Myers Jackson is well known for auctioning homes that people move and ... the planet. The luxury home market is alive and well and there are mansions ... of “11 Spyglass Hill Auction will enlighten you on the dynamics of how to ...
(Date:5/24/2017)... ... May 24, 2017 , ... ... female reproductive tract in which the endometrial lining of the uterus spreads ... and pain. Patients experiencing painful intercourse, painful periods, pelvic pain, or irregular ...
(Date:5/24/2017)... ... May 24, 2017 , ... ... ExtraHop to its solutions portfolio. ExtraHop delivers an analytics-first approach, layered with machine ... IT system, from the datacenter to the cloud to the edge. Through the ...
(Date:5/24/2017)... ... May 24, 2017 , ... Adelberg-Montalvan ... dentistry options for its patients on Long Island, New York. , Holistic ... being, and is one of the biggest trends in dentistry today. , ...
Breaking Medicine News(10 mins):
(Date:5/8/2017)... YORK , May 8, 2017 ... the transition from fee for service reimbursement. Black Book ... 2017. 1.       The Market for MIPS ... 77% of physician practices with 3 or more ... Technology Solutions by Q4. "Given the magnitude of the ...
(Date:5/4/2017)... Fix Inc. (" Fortuna "), a private, clinical-stage biotech ... need for embryonic and fetal stem cells by using direct ... Fortuna announced today the launch of its Scientific ... PhD; Father Kevin FitzGerald , S.J., PhD; Col. (R) ... Giordano , PhD. "We are excited and honored ...
(Date:5/4/2017)... 2017  A new tight-tolerance microextrusion medical tubing ... materials, is being launched by Natvar, a Tekni-Plex ... in recent years to service a wide variety ... More expensive materials such as glass and fluoropolymers ... to their ability to consistently hold tolerances. This ...
Breaking Medicine Technology: