Navigation Links
Platelets May Be The Source Of Gene Regulations

Researchers from University of Utah School of Medicine had reported that a key process in gene regulation could occur in human platelets. These are unique cells that are unusual because they don’t have a nucleus // (anucleate).

Scientists long have thought the transformation of pre-mRNA into mature mRNA—called splicing—happens only in a cell’s nucleus. But using stem cells from human umbilical cord blood to engineer the precursor cell that forms platelets and platelets isolated from the blood of study subjects, the Utah researchers found that splicing also takes place in the cytoplasm of circulating platelets.

The U researchers, who report their findings in the August edition of the journal Cell, also identified the pre-mRNA in blood platelets that codes for Interleukin 1? (IL-1?), a key protein in an ancient molecular system that plays major roles in inflammation, defense against infection, organ development, and disease. When blood platelets are activated through biochemical signals in response to injury, the IL-1? pre-mRNA is processed into the mature mRNA and then directs production of the critical inflammatory protein.

Finding that platelets can splice the IL-1? pre-mRNA was completely unexpected and emerged while the researchers were engaged in earlier studies of how platelets communicate with certain leukocytes (white blood cells). During that investigation the scientists had found evidence of platelets making new proteins, which led them to pursue the mechanisms that are involved.

Researchers theorize that splicing outside the nucleus is one of a number of intricate ways the body maintains more precise control over gene expression. Many of these control mechanisms are just coming to light.

Source: Newswse
'"/>




Page: 1

Related medicine news :

1. Quality Platelets and Improved Blood Availability No Longer a Pipe Dream
2. Startling Expose – Physicians Often Have No Regular Source Of Health Car
3. Indian Cherry: Richest Source of Vitiamin C
4. Urban Monkeys Source Of Virus Infections
5. Parents – Teen’s Most Reliable Source for Sex Educatin
6. Fruit And Vegetable Peels Are Rich Source Of Potent Antioxidants
7. New York- A haven For the Distressed or a Source of Distress?
8. Results of Clinical Trials Vary According to Source of Funding
9. Source of obesity linked to eating pattern!
10. Mushrooms are Rich Source of Antioxidants
11. Bacteria Killed By Radiation Serves As an Effective Source of Vaccine
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Platelets May The Source Gene Regulations

(Date:6/3/2015)... evigilo, a world leader in delivering and developing ... by launching a new and enhanced content-centric website: ... logo depicting a sun-like image with a color movement ... Know. To Act. In time. The color palate, it ... borderless approach to alerting and delivering safety and sense ...
(Date:6/2/2015)... 2015 The JK-A0100EU secure smart card ... government, finance and healthcare. However, this keyboard can also ... control to enhance the security of their network. , ... authentication of a Smart Card before allowing access to ... card reader, the keyboard supports secure PIN entry. , ...
(Date:6/2/2015)... June 02, 2015 MEDIA ADVISORY, ... 571-319-9594 (cell) , Email: ewallace(at)mentalhealthamerica(dot)net , Breaking News: ... Mental Health Legislation at MHA Annual Conference Thursday ... Rep. Murphy to address the Mental Health America ... long-awaited updated version of the Helping Families in ...
(Date:6/2/2015)... June 02, 2015 Highly qualified dental care ... plan to drive prolific change in the dental tourism industry ... Team Dental Clinic offers a full range of superior ... structure for dental tourism. , Partnered with a top ... committed to advancing dentistry and has earned a reputation as ...
(Date:6/2/2015)... 02, 2015 UCLA Health and Exer ... to partner and expand urgent care services in Los ... by the University of California Board of Regents and ... allow UCLA Health to purchase a minority share of ... Calabasas, Newbury Park and Northridge and creates opportunity to ...
Breaking Medicine News(10 mins):Health News:Keep calm! evigilos' "sun" will come out tomorrow – to know, to act, in time. 2Health News:Introducing the New CHERRY JK-A0100EU Keyboard with Integrated Smart Card Reader for Access Control Security 2Health News:Congressman Tim Murphy to Unveil Details of New Mental Health Legislation at MHA Annual Conference Thursday 2Health News:Team Dental Clinic Unveils Plan to Drive Change in the Dental Tourism Industry 2Health News:Team Dental Clinic Unveils Plan to Drive Change in the Dental Tourism Industry 3Health News:UCLA Health Partners With Exer - More Than Urgent Care 2
... ... ... policies that would meet people’s needs and improve their lives, according to Thoraya Ahmed Obaid, ... can better track and make greater progress to achieve the Millennium Development Goals ...
... Menlo Park, CA and Geneva, Switzerland -- The International ... provide worldwide online access to the XVIII International AIDS ... 18-23, 2010. Kaiser -- an independent operating foundation and ... Menlo Park, Calif., USA -- is the official webcaster ...
... ... share their personal stories and utilizes social media to spread the word. , ... Newcastle, ME (Vocus) July 8, 2010 -- An effort ... special video project and upcoming book. The Social Security Stories Project is seeking story ...
... Tel ... with diminished ovarian reserve further confirms Center For Human Reproduction,s ongoing research on this ... (PRWEB) ... Tel Aviv University in Tel Aviv, Israel, confirmed previously published research by New York ...
... ... of healing through writing down her emotions , ... Honolulu, HI (Vocus) July 9, 2010 -- She transformed a truly depressing ... it’s my time!, her new book made available through Xlibris, author Mary V. Domingo boldly ...
... ... that Khoi Nguyen and Dennis McDowell have joined their executive sales staff in the ... with the area,s most influential hospitals and providers. Accel is the Company’s top tier ... and providers. , ...
Cached Medicine News:Health News:Everyone Counts: Quality Data Essential to Improving People's Lives, Says UNFPA 2Health News:Online coverage of XVIII International AIDS Conference to include daily webcasts, live coverage, podcasts and news recaps 2Health News:Project captures Social Security "Stories," Seeks Additional Submissions from Public 2Health News:Project captures Social Security "Stories," Seeks Additional Submissions from Public 3Health News:Tel Aviv University Fertility Research Confirms New York Center's DHEA Findings 2Health News:Tel Aviv University Fertility Research Confirms New York Center's DHEA Findings 3Health News:Moving On With A Pen 2Health News:HealthSmart Adds Experienced Professionals to Houston Sales Force 2
(Date:6/2/2015)... -- Research and Markets ( http://www.researchandmarkets.com/research/z9s8mp/laboratory ) has ... - Global Strategic Business Report" report to ... are provided for the period 2014 through 2020. ... these markets. Market data and analytics are derived ... primarily based on public domain information including company ...
(Date:6/2/2015)... BioDelivery Sciences International, Inc. (NASDAQ: BDSI ) ... Mark A. Sirgo , President and Chief Executive Officer ... Jefferies 2015 Global Healthcare Conference Tuesday, June 2 ... York City , NY The presentation will ... .  For those who are not available to listen to ...
(Date:6/2/2015)... Fla. , June 2, 2015  One hundred ... of Science in Nurse Anesthesia (MSNA) graduates of April ... their first attempt. The graduating class was composed of ... 2015.  The NCE is required of ... Nurse Anesthetist, and graduates of the MSNA program are ...
Breaking Medicine Technology:Laboratory Centrifuges - Global Strategic Business Report 2014-2020: Developed Markets Slowdown, While Emerging Markets Surge 2BioDelivery Sciences to Present at the Jefferies 2015 Healthcare Conference - Schedule Change 2BioDelivery Sciences to Present at the Jefferies 2015 Healthcare Conference - Schedule Change 3ADU's Master of Science in Nurse Anesthesia April 2015 Graduates Earn 100 Percent First Time Pass Rate on National Certification Examination 2
... , DURHAM, N.C., Sept. 8 ... formally notified Vatea Fund of the company,s achievement of a milestone ... September 1, 2009. The milestone is a Clinical Trial for Oxycyte ... With the achievement of the milestone, the agreement calls for ...
... BOZEMAN, Mont., Sept 8 LigoCyte Pharmaceuticals, Inc. ... clinical trial of its norovirus vaccine. The Phase I/II ... nasally-delivered, dry powder vaccine in healthy adults. The study will ... by including a live virus challenge of subjects that have ...
Cached Medicine Technology:LigoCyte Pharmaceuticals Initiates a Randomized, Double Blind, Placebo Controlled Norovirus Vaccine Study Including Live Virus Challenge 2LigoCyte Pharmaceuticals Initiates a Randomized, Double Blind, Placebo Controlled Norovirus Vaccine Study Including Live Virus Challenge 3
... Medline Has the Right Solution For Your ... clean and care tray features the latest ... this important infection control task. Designed by ... individual needs of each patient and caregiver. ...
... Right Solution For Your Tracheostomy Care Needs, ... tray features the latest components for efficient ... control task. Designed by clinicians, these latex-free ... each patient and caregiver. All of our ...
... and alternate care facilities with a ... which offer the finest in nursing ... the guidance of experienced nursing personnel, ... what is required for efficient and ...
... alternate care facilities with a wide ... offer the finest in nursing convenience ... guidance of experienced nursing personnel, these ... is required for efficient and quick ...
Medicine Products: