Navigation Links
Platelets May Be The Source Of Gene Regulations

Researchers from University of Utah School of Medicine had reported that a key process in gene regulation could occur in human platelets. These are unique cells that are unusual because they don’t have a nucleus // (anucleate).

Scientists long have thought the transformation of pre-mRNA into mature mRNA—called splicing—happens only in a cell’s nucleus. But using stem cells from human umbilical cord blood to engineer the precursor cell that forms platelets and platelets isolated from the blood of study subjects, the Utah researchers found that splicing also takes place in the cytoplasm of circulating platelets.

The U researchers, who report their findings in the August edition of the journal Cell, also identified the pre-mRNA in blood platelets that codes for Interleukin 1? (IL-1?), a key protein in an ancient molecular system that plays major roles in inflammation, defense against infection, organ development, and disease. When blood platelets are activated through biochemical signals in response to injury, the IL-1? pre-mRNA is processed into the mature mRNA and then directs production of the critical inflammatory protein.

Finding that platelets can splice the IL-1? pre-mRNA was completely unexpected and emerged while the researchers were engaged in earlier studies of how platelets communicate with certain leukocytes (white blood cells). During that investigation the scientists had found evidence of platelets making new proteins, which led them to pursue the mechanisms that are involved.

Researchers theorize that splicing outside the nucleus is one of a number of intricate ways the body maintains more precise control over gene expression. Many of these control mechanisms are just coming to light.

Source: Newswse
'"/>




Page: 1

Related medicine news :

1. Quality Platelets and Improved Blood Availability No Longer a Pipe Dream
2. Startling Expose – Physicians Often Have No Regular Source Of Health Car
3. Indian Cherry: Richest Source of Vitiamin C
4. Urban Monkeys Source Of Virus Infections
5. Parents – Teen’s Most Reliable Source for Sex Educatin
6. Fruit And Vegetable Peels Are Rich Source Of Potent Antioxidants
7. New York- A haven For the Distressed or a Source of Distress?
8. Results of Clinical Trials Vary According to Source of Funding
9. Source of obesity linked to eating pattern!
10. Mushrooms are Rich Source of Antioxidants
11. Bacteria Killed By Radiation Serves As an Effective Source of Vaccine
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Platelets May The Source Gene Regulations

(Date:4/28/2015)... 28, 2015 The buyer power score ... of 5, indicating a medium level of buyer power ... suppliers have equal power during negotiations. One factor helping ... purchasing a health insurance policy from an insurance carrier ... buyers can choose to self-fund their own policy or ...
(Date:4/28/2015)... St. Louis, Missouri (PRWEB) April 28, 2015 ... report that delves into the reality problem Americans ... of the population will need long-term care services as ... will need such care. , In the report, ... from organizations such as the American Health Care Association ...
(Date:4/28/2015)... OsteoRemedies®, LLC, Memphis, TN, offers ... of infected hip and knee arthroplasty. ... pre-formed, pre-loaded spacer with Gentamicin Antibiotics, for consistent ... Combined with a consistent process for polishing ... approved for temporary use for up to 180 ...
(Date:4/28/2015)... 2015 Enrollment in programs designed ... 2.2 million in April, according to the editors ... Medicare-Medicaid Dual Eligibles Database , an online subscription ... the dual-eligible community. This is a 14% increase ... initiatives in January, but only covers about a ...
(Date:4/28/2015)... (PRWEB) April 28, 2015 The PracticeMatch ... from 5:00 to 8:00 pm at the Sheraton Colonial Boston ... 50 hospitals, clinics and groups with career opportunities will be ... Attendees will enjoy free hors d’oeuvres and raffle prize drawings. ... says “Boston is an ideal location to hold a ...
Breaking Medicine News(10 mins):Health News:New Data for Group Health Insurance Procurement Category Market Research Report from IBISWorld 2Health News:New Data for Group Health Insurance Procurement Category Market Research Report from IBISWorld 3Health News:New Data for Group Health Insurance Procurement Category Market Research Report from IBISWorld 4Health News:SeniorCare.com Report: America Has a Major Misconception on Aging 2Health News:Enrollment in Duals Programs Increases 14%, New AIS Database Finds 2Health News:PracticeMatch to Host Physician Career Fair at Sheraton Colonial Boston North Hotel on May 6, 2015 2Health News:PracticeMatch to Host Physician Career Fair at Sheraton Colonial Boston North Hotel on May 6, 2015 3
... REFORM IMPLEMENTATION RECOMMENDS WAYS TO ENSURE ACCESS TO AFFORDABLE ... Full-Year Coverage, Combined Small Business and Individual Health Insurance ... New York, NY, May 19, 2011Modifications to ... and subsidies provided under the Affordable Care Act remain ...
... , WEDNESDAY, May 18 (HealthDay News) -- Long-term ... colon cancers in women with a high risk of breast ... drinking and physical activity affected the risk of several common ... because of family history of breast cancer, age and other ...
... , WEDNESDAY, May 18 (HealthDay News) -- Rep. Gabrielle Giffords, ... assassin, will undergo surgery Wednesday in Houston to replace the ... shooting, according to the Associated Press . This ... days after the three-term Democratic congresswoman from Arizona traveled to ...
... (HealthDay News) -- End-of-life care for older people with advanced ... Canadian province of Ontario, a new study says. U.S. ... much more use of hospital and emergency room services, according ... the Ontario Cancer Registry. The information was collected from people ...
... Rochester Medical Center researchers have pinpointed two genes that ... providing data to support a new investigational treatment that ... Tony Godfrey, Ph.D., a research associate professor of Surgery ... was published by the journal Clinical Cancer Research. ...
... form of childhood cancer acute lymphoblastic leukemia are ... best efforts and the most powerful modern cancer drugs. ... the University of California, San Francisco have uncovered the basis ... use to stay alive. Targeting this protein may be the ...
Cached Medicine News:Health News:New report on health reform implementation: How to ensure access to coverage is maintained 2Health News:New report on health reform implementation: How to ensure access to coverage is maintained 3Health News:Smoking Raises Odds for Cancer in Women Already at High Risk 2Health News:Rep. Giffords to Get Skull Patch in Latest Step in Recovery 2Health News:Rep. Giffords to Get Skull Patch in Latest Step in Recovery 3Health News:End-of-Life Care Differs Between U.S., Canada, Study Finds 2Health News: Researchers home in on genetic signature of esophageal cancer 2Health News: Researchers home in on genetic signature of esophageal cancer 3Health News:UCSF team discovers key to fighting drug-resistant leukemia 2Health News:UCSF team discovers key to fighting drug-resistant leukemia 3
(Date:4/28/2015)... April 28, 2015  Rosa & Co. LLC, a ... and simulation, today announced its pleasure to be lead ... of Quantitative Systems Pharmacology (QSP). The conference focuses on ... ... Rosa,s lead sponsorship is the ...
(Date:4/28/2015)... , April 28, 2015  People with acute coronary ... heart stent are prescribed an oral antiplatelet (OAP) therapy and ... in their heart stent (stent thrombosis), or even death.[3] Yet, ... percent of 275 ACS patients who were currently taking an ... their prescribed OAP therapy, even though most of them were ...
(Date:4/28/2015)... , April 28, 2015 The ... its sixth funding cycle for U.S.- Israel ... Energy Efficiency. To be considered, a project proposal ... a company and a university/research institution (one from the U.S. ... should have significant commercial potential and the project outcome should ...
Breaking Medicine Technology:Rosa & Co. is the Lead Partner for the Quantitative Systems Pharmacology (QSP) Congress in Basel, Switzerland and Will Present the Keynote Address 2Rosa & Co. is the Lead Partner for the Quantitative Systems Pharmacology (QSP) Congress in Basel, Switzerland and Will Present the Keynote Address 3Survey Finds Half of Heart Stent Patients Don't Take Their Oral Antiplatelet Medication As Prescribed 2Survey Finds Half of Heart Stent Patients Don't Take Their Oral Antiplatelet Medication As Prescribed 3Survey Finds Half of Heart Stent Patients Don't Take Their Oral Antiplatelet Medication As Prescribed 4Survey Finds Half of Heart Stent Patients Don't Take Their Oral Antiplatelet Medication As Prescribed 5Survey Finds Half of Heart Stent Patients Don't Take Their Oral Antiplatelet Medication As Prescribed 6Survey Finds Half of Heart Stent Patients Don't Take Their Oral Antiplatelet Medication As Prescribed 7Survey Finds Half of Heart Stent Patients Don't Take Their Oral Antiplatelet Medication As Prescribed 8Survey Finds Half of Heart Stent Patients Don't Take Their Oral Antiplatelet Medication As Prescribed 9Opportunities for Funding U.S.-Israel Cooperation for Renewable Energy and Efficiency 2
... Fla., Jan. 11 Florida Atlantic,University and Scripps ... on Wednesday, January 16 from 4-5:30 p.m. in ... Blobel, M.D., Ph.D.,is the 1999 recipient of the ... D. Rockefeller, Jr. Professor, The Rockefeller University, and,Investigator, ...
... Products Help Address Infection Control, WASHINGTON, Jan. ... hospital operations and minimize risks during times,of health ... that one of its,healthcare products, DuPont(TM) Corian(R) solid ... for its emergency department. The product,recently was incorporated ...
Cached Medicine Technology:Nobel Laureate Dr. Gunter Blobel to Speak at Florida Atlantic University 2Nobel Laureate Dr. Gunter Blobel to Speak at Florida Atlantic University 3DuPont Provides Technology for Washington Hospital Center's Emergency Department 2DuPont Provides Technology for Washington Hospital Center's Emergency Department 3DuPont Provides Technology for Washington Hospital Center's Emergency Department 4
... is an in vitro immunoassay intended for the ... associated antigen. It is indicated for use as ... in conjunction with cystoscopy or when prescribed for ... the FDA for prescription home use in February ...
... is a quantitative microplate enzyme immunoassay that detects ... have very small amounts of NMP22 protein in ... is often elevated in the urine of patients ... the disease. The use of the NMP22 protein ...
... Used to connect an ... infusion pump, and then ... in order to conduct ... with Laborie Medical Technologies ...
Used for cystometry and urethral pressure profilometry. A loop is employed to enhance catheter retention and stabilization within the bladder. Supplied sterile in peel-open packages. Intended for one...
Medicine Products: