ieve that these latest findings will have important diagnostic and therapeutic implications for the management of this disease,’ says Karumanchi.
Adds Benjamin Sachs, MBBS, DPH, Chief of the Department of Obstetrics and Gynecology at BIDMC, ‘Preeclampsia affects 200,000 pregnancies a year in the United States and often leads to premature births. Severe preeclampsia is one of the world’s leading causes of maternal and fetal mortality and poses a particular risk to women in developing countries. This new information provides us with another key piece of evidence as we work toward developing the means to diagnose, and eventually treat, this disease.’
Study coauthors include BIDMC investigators Shivalingappa Venkatesha, PhD, Chun Lam, MD, Jun-ichi Hanai, MD, PhD, Tadanori Mammoto, MD, PhD, Yuval Bdolah, MD, Kee-Hak Lim, MD, Hai-Tao Yuan, MD, Towia Libermann, PhD, Isaac Stillman, MD, Franklin Epstein, MD, Frank Sellke, MD, PhD, and Vikas Sukhatme, MD, PhD; Mourad Toporsian, PhD, and Michelle Letarte, PhD, of The Hospital for Sick Children, University of Toronto, Ontario, Canada; Yeon Kim, MD, and Roberto Romero, MD, of the National Institute of Child Health and Human Development, Bethesda, Maryland; Drucilla Roberts, MD, PhD, of Massachusetts General Hospital; and Patricia D’Amore, PhD, of Schepens Eye Research Institute, Boston.
This study was funded, in part, by grants from the National Institutes of Health and the Heart and Stroke Foundation of Ontario.
BIDMC has filed patents on methods of diagnosing and treating preeclampsia.
Source: Newswise
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