Navigation Links
Photodynamic Therapy can Scramble the Immune System to Fight Cancer Spread

A light-triggered cancer treatment called photodynamic therapy (PDT) may be able to treat advanced cancer at the same time as targeting local tumours , according to research published in the British Journal of Cancer today (Tuesday).

PDT is a relatively new way of treating cancer, still at an early stage of development and being researched in labs around the world. It uses drugs that are usually harmless but become highly effective at killing cancer cells when exposed to light. Shining light on a tumour after one of these drugs has been injected selectively activates the drug in that area, treating the cancer but avoiding some of the side effects associated with chemotherapy.

Researchers from the Roswell Park Cancer Institute in the US have now shown that one particular form of PDT might have the potential to do more than treat local tumours. In early studies using animal models, they found that treatment with PDT stimulated the immune system to move out and attack cancer cells elsewhere in the body.

Their research raises the prospect of using local PDT to treat cancer that has spread. Dr Sandra Gollnick, senior author of the research, explains: "We took laboratory models with tumours in the shoulder and lungs. This was to simulate advanced cancer that may start somewhere locally, like the shoulder, and spread to the lungs.

"Solely treating the tumours in the shoulder worked as normal for PDT. But it also sparked off an immune response that reduced the number of tumours in the lungs as well. We made sure this wasn't due to activated drug reaching the lung tumours, and we were able to identify the precise part of the immune system being activated.

"It's the first time this effect has been seen and explained in such detail, although other scientists have predicted that PDT could trigger an immune response."

Dr Lesley Walker, director of cancer information at Cancer Research UK, which o wns the British Journal of Cancer, said: "These early results were obtained using a specific line of cancer cells and using one particular type of PDT.

A lot more research is required before we will know the full potential of PDT. This type of lab work is interesting, however, because it raises the prospect of a future treatment that could be applied locally but then stimulate the bodys own defences to seek out and destroy similar cancer cells elsewhere in the system."


'"/>




Related medicine news :

1. Infections Of The Oral Cavity Can Be Treated By Photodynamic Therapy
2. Cancer Doctors Okays Controversial Prostate Therapy
3. Consensus on "Combination Therapy" for Breast Cancer
4. Gene Therapy shows promise in treating Hemophilia
5. "Make AIDS Therapy affordable" - Physicians demand
6. Hormone replacement Therapy a headache
7. Simple Therapy
8. Therapy for stopping the spread of cancer cells
9. Gene Therapy Destroys Pancreatic Cancer Cells
10. Letrozole Beats Tamoxifen in Breast Cancer Therapy
11. Garlic Supplements Impede HIV Therapy
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/26/2016)... ... May 26, 2016 , ... Cabot Corporation, Pfizer, and ... according to court documents and SEC filings. A jury has returned a ... American Optical Corporation, Case No. BC588866, Los Angeles County, California. The jury awarded ...
(Date:5/26/2016)... (PRWEB) , ... May 26, 2016 , ... ... in intellectual property (IP) to its specialty academic programs. , Answering to the ... college’s existing certificate programs in health law, and environmental and land use law. ...
(Date:5/26/2016)... ... May 26, 2016 , ... On Memorial Day, Hope For Heroes ... in military battle for the country. The nonprofit Hope For Heroes partnered with ... that empower independence for disabled military veterans, as well as police, firemen, and EMS ...
(Date:5/26/2016)... ... 2016 , ... Cardiac arrhythmia is a common complication following ... survival, reports a team of UPMC researchers in the largest study of its ... Thoracic and Cardiovascular Surgery, provide critical information that will hopefully lead to better ...
(Date:5/26/2016)... , ... May 26, 2016 , ... MadgeTech will be ... engineered, and manufactured in Warner, New Hampshire at the MadgeTech headquarters. With products sold ... monitoring solutions trusted by government agencies, including NASA. , In 2012, NASA strategically ...
Breaking Medicine News(10 mins):
(Date:5/24/2016)... Cirujanos holandeses han puesto en ... médicos a compartir sus mejores prácticas por el mundo ... médicos de Europa, África, Asia ... aplicación, que combina la transmisión en vivo con mensajería ... Educación   "Imagine un médico de Medicines ...
(Date:5/24/2016)... 24, 2016   , ... in overall bowel cleansing and superiority in ... leansing of the ascending ... , Norgine B.V. today announced new positive data from ... ascorbate bowel preparation) versus standard 2 litre PEG with ascorbate. The ...
(Date:5/24/2016)... -- ARANZ Medical  Ltd a specialist in ... been named the Coretex Hi-Tech Emerging Company of the Year ... Bruce Davey , CEO of ARANZ Medical says, "This ... to be recognised for the work we are doing to ... 35 countries around the world from Sub-Saharan Africa through to ...
Breaking Medicine Technology: