Navigation Links
Peptide Found in Human Blood Inhibits 60 Strains of HIV, Study Says

A peptide found in human blood inhibited 60 strains of HIV from infecting cells in laboratory tests, according to a study published Thursday in the journal Cell//, the San Francisco Chronicle reports. Researchers found the peptide can inhibit HIV strains that have developed resistance to existing medications --a discovery that could lead to the development of new HIV/AIDS drugs -- the Chronicle reports.

Frank Kirchhoff of the University of Ulm in Germany and colleagues found the peptide, which they call VIRIP, in the residue left in filters used by kidney dialysis patients to clean their blood. According to Kirchhoff, by altering two amino acids, VIRIP's antiviral potency increased one hundredfold. VIRIP attacks a protein, called GP-41 and found on the surface of HIV, that the virus uses to penetrate the surface of human cells, the Chronicle reports.

According to Warner Greene, director of the Gladstone Institute of Virology and Immunology who was not involved with the study, VIRIP stands out because it is collected from human blood. He added that the peptide might work synergistically with the antiretroviral drug Fuzeon, which also is known as enfuvirtide or T-20 and was approved by FDA in March 2003. Greene said that it is possible that VIRIP also has potential as an active ingredient for microbicides, which include gels, foams and creams that could be applied prior to sexual intercourse to prevent the sexual transmission of HIV and other sexually transmitted infections. VIRIP can be manufactured in lab settings and has been licensed by the German biotechnology company Viro Pharmaceuticals, whose scientific director is a co-author of the study. According to the Chronicle, Viro is conducting animal studies to determine if VIRIP is safe to test among humans.

Although the results so far "look promising," it will take at least five years of animal and human trials before a drug implementing VIRIP is available, according to Kirchhoff.

Related medicine news :

1. New Insight To The Role Of Peptide Signals
2. Discovery of Elevated Amyloid Peptide levels could lead to Alzheimer’s Preventio
3. Fluoride Found Effective in Osteoporosis
4. Implantable Contact Lens Found Safe and Effective
5. Cancer hazard Found With Animal-Based Nutrients
6. Processed Meat, Diabetes connection Found
7. Night Time Aspirin Regimen Found to Reduce Blood Pressure
8. Hydrotherapy Found to be Effective for Patients with Osteoarthritis
9. Hydrotherapy Found to be Effective for Patients with Osteoarthritis
10. Preventive Therapies Found to be More Effective in Managing Migraines
11. Common Cold Found to Fight Cancer
Post Your Comments:

(Date:11/27/2015)... ... November 27, 2015 , ... The rapid speed at ... people age, more care is needed, especially with Alzheimer’s, dementia and other cognitive ... being overworked. The forgotten part of this equation: 80 percent of medical care ...
(Date:11/27/2015)... ... November 27, 2015 , ... A team of Swiss ... to treat it. Surviving Mesothelioma has just posted the findings on the website. ... Zurich analyzed the cases of 136 mesothelioma patients who were treated with chemotherapy followed ...
(Date:11/27/2015)... ... 27, 2015 , ... An inventor, from Hopkinsville, Ky., thought ... at home, so he invented the patent-pending ELECTRONIC M.D. , The ELECTRONIC M.D. ... doing so, it could help to prevent potential overdose situations. As a result, ...
(Date:11/27/2015)... ... 2015 , ... "When I was traveling, I was very ... "Many people catch diseases simply from sitting on such dirty toilet seats. I ... germs." , He developed the patent-pending QUDRATECS to eliminate the need to sit ...
(Date:11/27/2015)... County, CA (PRWEB) , ... November 27, 2015 , ... ... season , The company is offering customers 10% off of their purchase of lice ... any treatment at full price. According to a company spokesperson. “Finding lice is a ...
Breaking Medicine News(10 mins):
(Date:11/27/2015)... , Pays-Bas, November 27, 2015 ... au traitement photodynamique au Bremachlorin contre le cancer ... approche consistant à combiner l,immunothérapie au traitement photodynamique ... --> Une nouvelle approche consistant ... contre le cancer avancé.    ...
(Date:11/27/2015)... 2015 --> ... online. The potential to save costs, improve treatment quality ... from fully exploited as yet. Here, particular emphasis is ... via mobile tablet or directly at the patients, bedside. ... ) -->      (Photo: ...
(Date:11/27/2015)... Ein neuer Kombinationsansatz vereint ... --> Ein neuer Kombinationsansatz vereint Immuntherapie ... --> Ein neuer Kombinationsansatz vereint Immuntherapie ... Clinical Cancer Research vom 6. November ... vom 6. November 2015 berichtet. --> ...
Breaking Medicine Technology: