Navigation Links
Peptide Found in Human Blood Inhibits 60 Strains of HIV, Study Says

A peptide found in human blood inhibited 60 strains of HIV from infecting cells in laboratory tests, according to a study published Thursday in the journal Cell//, the San Francisco Chronicle reports. Researchers found the peptide can inhibit HIV strains that have developed resistance to existing medications --a discovery that could lead to the development of new HIV/AIDS drugs -- the Chronicle reports.

Frank Kirchhoff of the University of Ulm in Germany and colleagues found the peptide, which they call VIRIP, in the residue left in filters used by kidney dialysis patients to clean their blood. According to Kirchhoff, by altering two amino acids, VIRIP's antiviral potency increased one hundredfold. VIRIP attacks a protein, called GP-41 and found on the surface of HIV, that the virus uses to penetrate the surface of human cells, the Chronicle reports.

According to Warner Greene, director of the Gladstone Institute of Virology and Immunology who was not involved with the study, VIRIP stands out because it is collected from human blood. He added that the peptide might work synergistically with the antiretroviral drug Fuzeon, which also is known as enfuvirtide or T-20 and was approved by FDA in March 2003. Greene said that it is possible that VIRIP also has potential as an active ingredient for microbicides, which include gels, foams and creams that could be applied prior to sexual intercourse to prevent the sexual transmission of HIV and other sexually transmitted infections. VIRIP can be manufactured in lab settings and has been licensed by the German biotechnology company Viro Pharmaceuticals, whose scientific director is a co-author of the study. According to the Chronicle, Viro is conducting animal studies to determine if VIRIP is safe to test among humans.

Although the results so far "look promising," it will take at least five years of animal and human trials before a drug implementing VIRIP is available, according to Kirchhoff.

Source-Kaisernetwork.org/B
'"/>




Related medicine news :

1. New Insight To The Role Of Peptide Signals
2. Discovery of Elevated Amyloid Peptide levels could lead to Alzheimer’s Preventio
3. Fluoride Found Effective in Osteoporosis
4. Implantable Contact Lens Found Safe and Effective
5. Cancer hazard Found With Animal-Based Nutrients
6. Processed Meat, Diabetes connection Found
7. Night Time Aspirin Regimen Found to Reduce Blood Pressure
8. Hydrotherapy Found to be Effective for Patients with Osteoarthritis
9. Hydrotherapy Found to be Effective for Patients with Osteoarthritis
10. Preventive Therapies Found to be More Effective in Managing Migraines
11. Common Cold Found to Fight Cancer
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... ... October 13, 2017 , ... Ellevate Network, the leading ... to advocate for action towards gender equality at their inaugural Summit in New York ... globe, and reached a social audience of over 3 million. To watch the Mobilize ...
(Date:10/13/2017)... ... October 13, 2017 , ... Talented host, ... lowdown on sciatica in a new episode of "Success Files," which is an ... and innovation and investigates each subject in-depth with passion and integrity. , Sciatica ...
(Date:10/13/2017)... ... ... “America On The Brink”: the Christian history of the United States and the loss ... author, William Nowers. Captain Nowers and his wife, Millie, have six children, ten ... the Navy. Following his career as a naval aviator and carrier pilot, he ...
(Date:10/12/2017)... ... October 12, 2017 , ... Planet Fitness, one of the largest ... its plans to open a flagship location in Covington, LA at 401 N. U.S. ... Go store next to Office Depot in the Holiday Square shopping center. Its location ...
(Date:10/12/2017)... ... 12, 2017 , ... The American College of Medical Informatics (ACMI) will present ... the Opening Session of AMIA’s Annual Symposium in Washington, D.C. AMIA’s Annual Symposium ... Collen, a pioneer in the field of medical informatics, this prestigious award is presented ...
Breaking Medicine News(10 mins):
(Date:9/23/2017)... -- Janssen Biotech, Inc. (Janssen) announced today that it ... Food and Drug Administration (FDA) for the Biologics License ... of moderately to severely active rheumatoid arthritis (RA). The ... to further evaluate the safety of sirukumab in the ... "We are disappointed by ...
(Date:9/19/2017)... Ky. , Sept. 19, 2017   ZirMed Inc ... predictive analytics, today announced that it has been ranked #1 ... Black Book™ Rankings 2017 User Survey. ZirMed was ... solution for large hospitals and medical centers over 200 beds ... Black Book,s healthcare technology user survey history. ...
(Date:9/12/2017)... and NEW YORK , Sept. 12, 2017 /PRNewswire/ ... ratings for global supply chains, has published the first annual edition of ... performance of more than 20,400 companies evaluated by EcoVadis, based on Scorecard ... and 2016. ... Global CSR Risk & Performance Index ...
Breaking Medicine Technology: