( or example were estimated to have a hi...)People Exposed To Lead Likely To Die From Brain Cancer,Health

or example, were estimated to have a high probability of exposure, but only medium intensity of exposure because their direct contact with leaded gasoline was not as great as the potential for contact. The jobs with the highest probability and intensity of lead exposure were painters and automobile mechanics. But firefighters, engineers, automobile assemblers, truck drivers, plumbers, welders, and printers or typesetters were all among those individuals with some likelihood of lead exposure, according to the NCI matrix.

When Van Wijngaarden applied the matrix to nearly 318,000 people and followed their cancer rates for nine years, he found 119 brain cancer deaths. The death rate among people with jobs that potentially exposed them to lead was 50 percent higher than unexposed people, and the number of deaths was larger than in many previous studies, van Wijngaarden said. Other trends that emerged were slightly higher death rates among less educated and married individuals.

Scientists have suspected for years that lead is a carcinogen, which passes through the blood-brain barrier, making the brain especially sensitive to the toxic effects of lead. Van Wijngaarden is continuing his research with a pilot study to measure the actual bone-lead levels in people who have been diagnosed with brain tumors.

"My interest is in exploring the long-term implications of lead exposure," van Wijngaarden said. "Lately, a lot of the information about lead and its toxicity has focused on children. We do know that in young people it can cause acute illness and behavioral problems. But what is under appreciated, I believe, are the chronic health effects."

Source-Eurekalert
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