Navigation Links
Passive Cigarette Smoking Increases Isoprostane Formation

During the recent past, the risk of passive smoking has been widely recognized. Passive smoking has been demonstrated //to exert a variety of deleterious effects, associated with an increased risk of coronary heart disease eventually resulting in vascular damage.

Isoprostanes, a reliable marker of in vivo oxidation injury, have been shown to increase in active cigarette smoking. However, the data for passive smoking are lacking.

Recently, researchers from Austria and Greeec examined the isoprostane 8-epi-PGF2a in 12 smokers and non-smokers exposed daily to passive cigarette smoke for 12 days. Plasma samples stored at liquid nitrogen from people having been examined earlier were used.

Prevalues of 8-epi-PGF2a were found to be higher in cigarette smokers. Exposure to passive smoking caused a significant increase in 8-epi-PGF2a in non-smokers, while in smokers there was only a trendwise increase. After repeated passive smoke exposure, 8-epi-PGF2a in non-smokers approached the respective values of smokers.

There was a significant correlation of 8-epi-PGF2a to the thromboxane (plasma, serum, conversion from exogenous precursor, 11-dehydro-TXB2) parameters (MDA, HHT- conversion) examined in these patients before.

The findings, to be published in the journal Life Sciences (available online 13 September 2005) document a significant temporary increase in in vivo oxidation injury due to passive smoke favouring development and/or progression of vascular disease.

Apparently, repeated but not single exposure to passive smoking introduces a significantly large number of radicals into the human body. After rapid consumption of antioxidants lipid peroxidation products including isoprostanes are accumulated in blood and finally in vascular tissue exerting deleterious effects.

The authors conclude that besides activation of platelet function and the thromboxane synthesis, in vivo oxidation injury may be an i mportant additional major player in the pathogenesis of cardiovascular disease secondary to passive smoke exposure.

What is passive smoking?

A non smoker who breathes other people's smoke is called passive smoking. It is also called as involuntary or secondhand smoking.


'"/>




Related medicine news :

1. Passive smoking affects respiratory system
2. Passive smoking may be harmless
3. Passive Smoking A Health Hazard Unnoticed
4. Passive Smoking Makes Kids Prone To Respiratory Illness
5. Passive Immunization to prevent Bird flu infection
6. Passive smoking declared as Toxic in California
7. Passive Immunotherapy Could Prevent Avian Flu from Affecting Humans
8. Passive Smoking Worsens Allergies
9. Passive Smokers may Face Higher Heart Disease Risk
10. Cancers of Colon & Rectum linked to Cigarette Smoking
11. Low-Tar Cigarettes As dangerous As High-Tar Cigarettes
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... (PRWEB) , ... October 13, 2017 , ... Apple ... care services, staged a mock evacuation of the facility as part of a disaster ... Fire Department, Echo Hose EMS and Shelton City Emergency Manager, as well as the ...
(Date:10/13/2017)... , ... October 13, 2017 , ... Global Healthcare Management’s ... Alexandria Park in Milford, NJ. This free event, sponsored by Global Healthcare Management’s ... The fun run is geared towards children of all ages; it is a ...
(Date:10/13/2017)... ... October 13, 2017 , ... “The Journey: From the ... danger possible to save lost souls in the Philippines. “The Journey: From the Mountains ... a dedicated teacher of the Bible. She has taught all ages and currently teaches ...
(Date:10/12/2017)... ... October 12, 2017 , ... Planet Fitness, one of the largest and ... plans to open a flagship location in Covington, LA at 401 N. U.S. Highway ... store next to Office Depot in the Holiday Square shopping center. Its location allows ...
(Date:10/12/2017)... ... 2017 , ... Asante, a nationally recognized health system in ... existing home health joint venture through an agreement, effective October 1, 2017, to ... home health company with Asante, delivering clinically integrated care, for the past eight ...
Breaking Medicine News(10 mins):
(Date:10/10/2017)... -- NDS received FDA 510(k) clearance in May 2017 for its highly ... designed for endoscopy environments. An innovative secondary monitor solution, ZeroWire ... support the improvement of patient outcomes, procedural efficiency, and the lowering ... ... ...
(Date:10/4/2017)... 4, 2017  South Korean-based healthcare product Development Company ... "cprCUBE" on Kickstarter. The device will educate the user ... with better efficiency compared to the dated and pricey ... on efficacy of the compression for a more informed ... goal to raise $5,000. ...
(Date:10/2/2017)... 2017  Eli Lilly and Company (NYSE: ... third quarter of 2017 on Tuesday, October 24, 2017. ... day with the investment community and media to further ... call will begin at 9 a.m. Eastern time. Investors, ... webcast of the conference call through a link that ...
Breaking Medicine Technology: