Navigation Links
Passive Cigarette Smoking Increases Isoprostane Formation

During the recent past, the risk of passive smoking has been widely recognized. Passive smoking has been demonstrated //to exert a variety of deleterious effects, associated with an increased risk of coronary heart disease eventually resulting in vascular damage.

Isoprostanes, a reliable marker of in vivo oxidation injury, have been shown to increase in active cigarette smoking. However, the data for passive smoking are lacking.

Recently, researchers from Austria and Greeec examined the isoprostane 8-epi-PGF2a in 12 smokers and non-smokers exposed daily to passive cigarette smoke for 12 days. Plasma samples stored at liquid nitrogen from people having been examined earlier were used.

Prevalues of 8-epi-PGF2a were found to be higher in cigarette smokers. Exposure to passive smoking caused a significant increase in 8-epi-PGF2a in non-smokers, while in smokers there was only a trendwise increase. After repeated passive smoke exposure, 8-epi-PGF2a in non-smokers approached the respective values of smokers.

There was a significant correlation of 8-epi-PGF2a to the thromboxane (plasma, serum, conversion from exogenous precursor, 11-dehydro-TXB2) parameters (MDA, HHT- conversion) examined in these patients before.

The findings, to be published in the journal Life Sciences (available online 13 September 2005) document a significant temporary increase in in vivo oxidation injury due to passive smoke favouring development and/or progression of vascular disease.

Apparently, repeated but not single exposure to passive smoking introduces a significantly large number of radicals into the human body. After rapid consumption of antioxidants lipid peroxidation products including isoprostanes are accumulated in blood and finally in vascular tissue exerting deleterious effects.

The authors conclude that besides activation of platelet function and the thromboxane synthesis, in vivo oxidation injury may be an i mportant additional major player in the pathogenesis of cardiovascular disease secondary to passive smoke exposure.

What is passive smoking?

A non smoker who breathes other people's smoke is called passive smoking. It is also called as involuntary or secondhand smoking.


'"/>




Related medicine news :

1. Passive smoking affects respiratory system
2. Passive smoking may be harmless
3. Passive Smoking A Health Hazard Unnoticed
4. Passive Smoking Makes Kids Prone To Respiratory Illness
5. Passive Immunization to prevent Bird flu infection
6. Passive smoking declared as Toxic in California
7. Passive Immunotherapy Could Prevent Avian Flu from Affecting Humans
8. Passive Smoking Worsens Allergies
9. Passive Smokers may Face Higher Heart Disease Risk
10. Cancers of Colon & Rectum linked to Cigarette Smoking
11. Low-Tar Cigarettes As dangerous As High-Tar Cigarettes
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:7/28/2017)... ... ... The DuPage County law firm of Mirabella Kincaid Frederick & Mirabella, ... Cusack joins the team ready to provide clients with vigorous representation in a number ... Illinois, with a BA in Social Work. She earned her JD from Western Michigan ...
(Date:7/28/2017)... ... 2017 , ... Gocella Insurance Agency, a Cheektowaga based partnership ... in and around the greater Buffalo metropolitan area, is announcing the firm’s 25th ... The Make-A-Wish Foundation is an internationally recognized nonprofit that works to improve the ...
(Date:7/27/2017)... Denville, NJ (PRWEB) , ... July 27, 2017 ... ... now a Diplomate of the American Board of Oral Implantology/Implant Dentistry (ABOI/ID). After ... one of the nation’s leading providers of dental implants . Dr. Kimowitz ...
(Date:7/27/2017)... Viejo, CA (PRWEB) , ... July 27, 2017 , ... ... Cut Pro X . This Final Cut Pro X exclusive features transitions that contain ... and add rotation to the transition using intuitive drop-down menus. TransPanel Volume 4 makes ...
(Date:7/27/2017)... ... July 27, 2017 , ... ... announces the internal promotion of Elrene Clinkscales to Vice President of Revenue Cycle ... Remittance Management, reporting to Derek Morkel, chief executive officer (CEO). , Elrene has ...
Breaking Medicine News(10 mins):
(Date:7/24/2017)... ARMONK, N.Y. , July 24, 2017 IBM ... in the Gartner Magic Quadrant for Solid-State Arrays (SSA) for ... According to Gartner, "Vendors in the ... Execute and Completeness of Vision. A vendor in the Leaders ... capabilities needed to drive the acceptance of new technologies. These ...
(Date:7/21/2017)...  Endo International plc (NASDAQ: ENDP ) ... its manufacturing network, the Company will be ceasing operations ... Huntsville, Alabama . The closure of the ... 12 to 18 months. The Huntsville ... commoditized products and these restructuring actions are intended to ...
(Date:7/17/2017)... 17, 2017  MedX Holdings, Inc., the manufacturer and ... and rehabilitation equipment, today announced the national roll out ... considered the gold standard for the treatment of low ... strengthening equipment. How ... physician or practice who prescribe the MedX Home Back ...
Breaking Medicine Technology: