Navigation Links
Painkillers Linked to Still More Problems

Two recent studies have offered still more evidence of the dangers linked with certain painkillers including kidney problems// in addition to the heart concerns that was already raised with the drug marketed as Vioxx.

One report from Brigham and Women's Hospital, and Harvard Medical School, Boston, said that an analysis of 114 studies that involved over 116,000 people showed that rofecoxib commonly known as Vioxx "was associated with increased renal and (heart) arrhythmia risks."

The reason as to why the drug would cause kidney damage is still unclear. In September 2004 Merck & Co Inc. withdrew Vioxx from the market after a three-year study revealed that it doubled the risk of heart attack and strokes in patients taking it for at least 18 months.

Another report from the University of Newcastle, New South Wales, Australia, following a review of 23 studies confirms the findings of an increased risk of heart problems with Vioxx that could be found "during the first 30 days of treatment in contrast to the the original suggestion that the vascular risk was only seen after 18 months."

Merck, however, facing more than 11,500 product liability lawsuits from people with claims of problems from Vioxx, has said that it still believes the data confirm the increased heart risk begins only after the medicine had been taken for 18 months.

The Australian analysis also found that celecoxib commonly sold as Celebrex and marketed by Pfizer Inc. was not associated with heart problems at a dose no greater than 200 milligrams a day.

Its review has also raised serious questions about the safety of diclofenac, an older (analgesic) drug marketed more in Europe than the United States.

The report added, "In conclusion ... diclofenac seems to share this risk and, unlike celecoxib, it appears to be harmful at commonly used doses. We believe there are grounds for reviewing its regulatory status."

The research details hav e been published in this week's Journal of the American Medical Association.

David Graham, a physician who works for the U.S. Food and Drug Administration said, "What does this all mean? First, rofecoxib (Vioxx) increases the risk of acute myocardial infarction at low and high doses." There is no initial 18-month period of immunity from risk."

He added that Celebrex "also increases (heart) risk at doses higher than 200 mg/d ... several other NSAIDs (non-steroidal anti-inflammatory drugs) increase risk, including ... diclofenac and meloxicam ... indomethacin and probably ibuprofen," while studies agree that naproxen is "neutral" for heart attack risk.

Graham added that for most patients with arthritis or other conditions requiring chronic pain relief "naproxen appears to be the safest NSAID choice from a cardiovascular perspective." Naproxen is commonly known as Aleve and marketed by Bayer Corp.
NLA
'"/>




Related medicine news :

1. Painkillers Do Not Shorten Dying Patients Lives
2. Painkillers may protect against Alzheimers disease
3. Painkillers may raise miscarriage risk
4. Painkillers Increase Risk of Miscarriage
5. In The Habit Of Taking Painkillers For Your Chronic Headache? Time To Switch Over
6. Aspirin Might Counter Side Effects of Cox-2 Painkillers
7. Painkillers Lead To Liver Failure
8. Study Advocates Use Of Oral Painkillers After Cesarean Section
9. Overdose of Opioid Painkillers Can Kill Pain and The Patient
10. UK Recommendations On Painkillers Flaunted
11. Painkillers—New and Old—Increase the Risk for Heart Attak
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/2/2016)... ... May 02, 2016 , ... Eating Recovery Center’s Insight Behavioral Health ... anxiety disorders, has rebranded its eating disorder program under a new name: Eating Recovery ... facility on May 16. , To celebrate, ERC Chicago will host a ribbon-cutting ...
(Date:5/2/2016)... , ... May 02, 2016 , ... ... Data Book for the 2016 Main Residency Match® (“the Match”), the system through ... United States teaching institutions. A record-high 30,750 positions were placed in the 2016 ...
(Date:5/2/2016)... ... May 02, 2016 , ... East Los Angeles dentist , ... can visit Dr. Assili to receive any dental extraction treatment for $40 off the ... June 30, 2016. With the lower price, patients can more easily afford extractions to ...
(Date:5/2/2016)... ... May 02, 2016 , ... ... new Specialty Pharmacy Patient Satisfaction Award that will recognize specialty pharmacies for their ... from Zitter Health Insights’ Specialty Pharmacy Patient Satisfaction Survey compiled throughout 2016. Results ...
(Date:5/2/2016)... PORT RICHEY, Fla. (PRWEB) , ... ... ... experts and medical researchers report that many commonly used prescription medications, including ... loss (1). To mitigate these risks, Novus Medical Detox Center —a ...
Breaking Medicine News(10 mins):
(Date:4/29/2016)... BERLIN , April 29, 2016 ... world-leading glyco-biology expertise, today announces the appointment of Dr. ... Dr. Zurlo is an oncologist with many years ... pharmaceutical and biotechnology industries. His last role was at ... Member of the Executive Board. Previously Dr. Zurlo held ...
(Date:4/28/2016)... , April 28, 2016  While Abbott,s ... complement the company,s valve repair and stent business, ... also places Abbott more firmly into patient monitoring.  ... the fastest growing device areas, with double-digit growth ... recent report,  Advanced Remote Patient Monitoring ...
(Date:4/28/2016)... April 28, 2016 ... George Phillips und Stephen Schmidt ... ArisGlobal®, ein führender Anbieter cloudbasierter ... heute bekannt, dass neue Führungskräfte zum Team ... sind, die vielfältige Erfahrungen mitbringen.  Dies wird ...
Breaking Medicine Technology: