Navigation Links
PET Scans Help In Monitoring Progress of Lung Inflammation

Scientists at Washington University School of Medicine in St. Louis say that a noninvasive approach towards assessing lung inflammation could hasten the process of developing drugs for cystic fibrosis and pneumonia. // Positron emission tomography (PET) scans were used to monitor artificially induced inflammation in the lungs of healthy volunteers.

"Until now, when we wanted to assess whether a new drug decreased lung inflammation, the options for specifically measuring active inflammation were not pleasant," says lead author Delphine Chen, M.D., chief resident in nuclear medicine at the medical school's Mallinckrodt Institute of Radiology. "We could perform a bronchoscopy and gather samples directly from the breathing passages, or we could have patients inhale a saline solution and cough it back up." Researchers say that the process of monitoring each step in the inflammatory process will help in formulating drugs to stop the same. Their findings are published in he Journal of Applied Physiology. "Full-scale clinical trials are costly in terms of both time and dollars spent, and right now it's very difficult to find intermediate steps that allow us to build confidence in a drug's effectiveness before taking that plunge," said senior author Daniel P. Schuster, M.D., professor of medicine and of radiology. He added that drugs could now be tested in smaller groups of volunteers. "If the drug passes those tests, then you can say, okay, let's see in a full-scale trial if the drug actually has an impact on some important patient-centered outcome like mortality or disease progression," he added. Main Article: Chen DL, Rosenbluth DB, Mintun MA, Schuster DP. FDG-PET imaging of pulmonary inflammation in healthy volunteers after airway instillation of endotoxin. The Journal of Applied Physiology, online publication.
'"/>




Page: 1

Related medicine news :

1. Brain Scans Help Predict Alzheimers Disease
2. PET Scans Found To Reveal Hidden Cancers
3. CT Scans Found To Increase The Risk Of Cancer
4. CT Scans Said to Accurately Detect Small Cancers
5. CT Scans Found To Do More Harm Than Good
6. Radiologists Find New CT Scans Useful
7. Consultant Radiologist, Apologized For Misreporting Breast Cancer Scans
8. PET Scans Could Predict Treatment Outcomes In Cancer
9. Research Scans Explain Why People Crave For Food
10. Hidden Mysteries Of The Universe - US Telescope Scans
11. MRI Scans in Premature Infants Can Predict Future Developmental Delays
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... , ... October 13, 2017 , ... The American Board ... become its next President and Chief Executive Officer, succeeding Dr. James C. Puffer upon ... beginning July 1, 2018 until Dr. Puffer’s retirement at the end of 2018. Upon ...
(Date:10/13/2017)... ... October 13, 2017 , ... ... ‘17, and Jennifer Huggins, PharmD ’17, along with clinical associate professor Janice ... of cardiovascular diseases during the 15th Annual Women’s Health Conference. The SIU ...
(Date:10/13/2017)... SAN LUIS OBISPO, Calif. (PRWEB) , ... October 13, 2017 , ... ... with Alzheimer’s or dementia. However, many long-term care insurance companies have a waiver for ... mean is the 90-day elimination period, when the family pays for care, is often ...
(Date:10/13/2017)... ... October 13, 2017 , ... Global Healthcare Management’s 4th ... Park in Milford, NJ. This free event, sponsored by Global Healthcare Management’s CEO, ... The fun run is geared towards children of all ages; it is a non-competitive, ...
(Date:10/13/2017)... ... October 13, 2017 , ... ... Software Development, has been awarded a contract by the Center for Medicare and ... aims to accelerate the enterprise use of Agile methodologies in a consistent and ...
Breaking Medicine News(10 mins):
(Date:9/27/2017)... for their devotion to personalized service, SMP Pharmacy Solutions announces ... the South Florida Business Journal,s 50 Fastest-Growing Companies, and listed ... national specialty pharmacy has found its niche.  To that end, ... honored by SFBJ as the 2017 Power Leader in Health ... his award in October, Bardisa said of the three achievements, ...
(Date:9/25/2017)...   Montrium , an industry leader in ... IQPC Trial Master Files & Inspection Readiness Conference ... Clinical Services has selected eTMF Connect ... EastHORN, a leading European contract research organization (CRO), ... to enable greater collaboration with sponsors, improve compliance ...
(Date:9/23/2017)... Sept. 22, 2017 Janssen Biotech, Inc. (Janssen) ... letter from the U.S. Food and Drug Administration (FDA) ... sirukumab for the treatment of moderately to severely active ... clinical data are needed to further evaluate the safety ... active RA. ...
Breaking Medicine Technology: