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PET Scan find the Area of Brain Responsible for Anorexia Nervosa

od and drug use on the other," added Dr. Frank, a fellow in child psychiatry.

More research is needed to address the many questions that remain, including what causes the dopamine receptors to be overactive in the first place. Genetic studies could yield some answers. Indeed, a study supported by the Price Foundation, which was recently published in the online edition of Neuropsychopharmacology, found alterations in genes for the D2 receptor in some individuals with anorexia nervosa. Dr. Kaye is a co-author of that paper and principal investigator of the Price Foundation studies, including a new multi-center study that is now recruiting families with two or more members who have or had anorexia nervosa to help identify the genes that contribute to the eating disorder.

In addition to Drs. Kaye and Frank, other authors include Carolyn C. Meltzer, M.D., Julie C. Price, Ph.D., Chester A. Mathis, Ph.D., Jessica Hoge and Scott Ziolko, all of the University of Pittsburgh School of Medicine department of radiology; Ursula F. Bailer, M.D., Shannon E. Henry and Angela Wagner, M.D., from the University of Pittsburgh School of Medicine department of medicine; Lisa Weissfeld, Ph.D., from the University of Pittsburgh Graduate School of Public Health department of biostatistics; Wayne Drevits, M.D., from the National Institute of Mental Health; and Nicole Barbarich-Marsteller from the State University of New York at Stony Brook. The research was supported by the National Institute of Mental Health (NIMH) and the Price Foundation. More information about the multi-center study funded by the NIMH can be found at www.angenetics.org.

Contact: Lisa Rossi
RossiL@upmc.edu
Phone: 412-647-3555
Fax: 412-624-3184
Jocelyn Uhl
UhlJH@upmc.edu
Phone: 412-647-3555
Fax: 412-624-3184

Source of News Extract: Eureka Alert
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