Navigation Links
Osteoarthritis May be Sign of Faster “Biological Ageing

Osteoarthritis, the degenerative inflammatory bone disease, may be a sign of faster “biological ageing,” suggests research published ahead // of print in the Annals of the Rheumatic Diseases.

The authors base their findings on a study of almost 1100 people, aged between 30 and 79. Most of them were female twins.

X-rays of both hands were taken of all participants to check for signs of osteoarthritis and a blood sample was taken to assess “biological ageing” in white cell DNA.

Biological ageing is likely to be reflected by the gradual shortening of telomeres, the length of DNA which caps the tips of chromosomes. A host of factors make them shorten over time, including insufficient repair of the damage caused by oxygen free radicals (oxidative stress).

Oxygen free radicals are the unstable molecules produced as a by-product of normal bodily processes, as well as external factors, such as tobacco, alcohol, and sunlight.

Osteoarthritis is the most common form of arthritis, with the hands being one of the sites most often affected. Its frequency rises dramatically with age, but it is still not known exactly what causes it.

Unsurprisingly, the findings showed that white cell telomere lengths were associated with chronological age. The older a person was, the shorter they were.

But among the 160 people with hand osteoarthritis, the telomere length was significantly shorter than among those without the disease, even after taking account of influential factors, such as obesity, age, sex, and smoking.

All those with hand osteoarthritis were over 50, and the amount of telomere shortening was equivalent to that accrued over 11 years in healthy people (178 base pairs).

Telomere length was also significantly associated with the severity of osteoarthritis. The more severe the disease, the shorter was the telomere length.

The authors suggest that both the ageing pr ocess and osteoarthritis share biological factors in common, including oxidative stress and low level chronic inflammation.

Source-Newswise
RM
'"/>




Related medicine news :

1. New device for discerning Osteoarthritis
2. Osteoarthritis and Estrogen are connected
3. Hyaluronan supplementation therapy for Knee Osteoarthritis
4. Leech Therapy for Osteoarthritis
5. Hydrotherapy Found to be Effective for Patients with Osteoarthritis
6. Hydrotherapy Found to be Effective for Patients with Osteoarthritis
7. Pain Relief For Osteoarthritis Patients
8. The Use Of Ointments For The Treatment Of Osteoarthritis Questioned
9. New Drug Found To Benefit Patients With Osteoarthritis
10. Water Exercise Found to be Effective for Patients with Osteoarthritis
11. Hydrotherapy Could Be Effective For Osteoarthritis
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/10/2016)... St. Louis, Missouri (PRWEB) , ... February 10, ... ... 11-14, 2016, in San Diego, will bring together more than 200 of the ... in healthcare for the future. , “The true benefit of the Forum is ...
(Date:2/10/2016)... ... 10, 2016 , ... AHRA: The Association for Medical Imaging ... Fox will serve as keynote speaker at the organization’s 2016 Spring Conference. Fox’s ... more effectively communicate with their own organizational staff and leadership. , “I ...
(Date:2/10/2016)... ... February 10, 2016 , ... Everseat has joined the award-winning ... to physicians. The integration will enable Allscripts users to post open appointments to ... mobile app. , The partnership gives Everseat substantial added power to help Allscripts ...
(Date:2/10/2016)... ... February 10, 2016 , ... The recreational use of marijuana has been ... still face a lot of restrictions as to where they can smoke pot. ... use” and that cannabis “may not be consumed openly or publicly.” , Given the ...
(Date:2/10/2016)... ... February 09, 2016 , ... According to a recent article published ... number of patients under the age of 30. According to Southern California based medical ... and may indicate an overall shift in the rapidly growing social acceptance of cosmetic ...
Breaking Medicine News(10 mins):
(Date:2/10/2016)... The campaign aims to ensure 2,50,532 ... reach the milestone of their 5 th birthday   --> ... between the ages of 2 - 5 years reach the ... campaign aims to ensure 2,50,532 children ... of their 5 th birthday   India , ...
(Date:2/9/2016)...  Misonix, Inc. (NASDAQ: MSON ), an ... markets innovative therapeutic ultrasonic products for spine surgery, ... surgery and other surgical applications, today announced financial ... half of fiscal year 2016 ended December 31, ... --> Highlights for the second quarter and ...
(Date:2/9/2016)... YORK, Pa., Feb. 9, 2016  Unilife Corporation ("Unilife" or "Company") ... of injectable drug delivery systems, today announced its financial results for ... 2015). ... Revenue for the ... million in the same period last year.  Cash receipts from customers ...
Breaking Medicine Technology: