Navigation Links
Oral Medicine Found To Remove Excess Iron in the Body

People suffering from severe chronic anemias and those with beta-thalassemia need frequent blood transfusions to remain healthy. // But the problem they frequently encounter is that due to transfusions there is an increase in the iron content in the body. This results in heart and liver failure.

The traditional treatment to remove excess iron is a time consuming process. Hence researchers studied deferasirox which is a new drug to treat patients suffering from chronic iron overload. The results of the study would be published in the month of May in the journal Blood. As of now the therapy to remove excess iron from the body is deferoxamine. This is administered for as long as the patient continues to receive blood transfusions, which, for many patients, can be for the rest of their lives. But the drug is very effective and safe.

The only drawback is that the drug has to be delivered by slow subcutaneous or intravenous infusion for eight to 12 hours a night over a period of five to seven days. On the other hand deferasirox is available in a once-daily, drinkable format, providing a promising alternative. Maria Domenica Cappellini, MD, of the University of Milan, Italy, and lead study author said that this reduces the strain on those patients especially children who require frequent blood transfusions help them to lead a normal and healthy life. She and her colleagues compared the efficacy and safety of the two drugs. Both children and adults participated in the study were diagnosed with chronic iron overload. People with beta-thalassemia, an inherited blood disorder, were selected for this study because complications of chronic iron overload have been best studied in those with this disease.

All participants continued receiving regular blood transfusions to treat beta-thalassemia throughout the year-long study. Participants were divided into two groups. In one group 290 patients received deferoxamine infusions five days a week and in t he second group 296 patients drank deferasirox dissolved in water each day before breakfast. Drug dosages were determined by each patient's liver iron concentration (LIC) level. The primary goal of the trial was to reduce LIC levels in those with high values and maintain LIC levels in those with low values. In the end of the study Deferasirox proved to be equally as effective as deferoxamine in patients receiving the highest doses of the drug. Deferasirox was generally well-tolerated with mild and common side effects such as skin rash and gastrointestional problems (abdominal pain, vomiting, diarrhea, and constipation).


'"/>




Related medicine news :

1. Nobel Prize for Medicine shared by Three scientists
2. Prince Charles lends support to Alternative Medicine
3. Healthy Medicine Or Harmful Intoxicant?
4. Medicines on the move
5. A surge in Lifestyle Medicine
6. Does Your Prescription Have An Inappropriate Medicine?
7. The Use Of Alternative Medicine On The Rise
8. New Medicine For Parkinson’s disease
9. Advent of New, More Effective and Personalized Medicines
10. Combing Hair More Effective Than OTC Medicine For Head Lice
11. Heart Patients Use Alternative Medicine
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... ... October 13, 2017 , ... The American Board of Family Medicine's (ABFM) Board ... Chief Executive Officer, succeeding Dr. James C. Puffer upon his retirement. Dr. Newton will ... Dr. Puffer’s retirement at the end of 2018. Upon assuming the role of President ...
(Date:10/13/2017)... ... October 13, 2017 , ... ... PharmD ‘17, and Jennifer Huggins, PharmD ’17, along with clinical associate professor ... prevention of cardiovascular diseases during the 15th Annual Women’s Health Conference. The ...
(Date:10/13/2017)... (PRWEB) , ... October 13, 2017 , ... Many families ... However, many long-term care insurance companies have a waiver for care if the client ... elimination period, when the family pays for care, is often waived, so the benefits ...
(Date:10/13/2017)... ... 13, 2017 , ... Global Healthcare Management’s 4th Annual Kids Fun Run brought ... This free event, sponsored by Global Healthcare Management’s CEO, Jon Letko, is aimed at ... towards children of all ages; it is a non-competitive, non-timed event, which is all ...
(Date:10/13/2017)... ... 13, 2017 , ... Coveros, a leader in agile coaching ... contract by the Center for Medicare and Medicaid Services (CMS). The Enterprise Agile ... of Agile methodologies in a consistent and high value manner across CMS programs. ...
Breaking Medicine News(10 mins):
(Date:9/27/2017)... , Sept. 27, 2017  DarioHealth Corp. (NASDAQ: DRIO), a leading global ... that its MyDario product is expected to appear on The Dr. Oz ... Dr. Oz Show airs in your area: http://www.doctoroz.com/page/where-watch-dr-oz-show ... The nine-time Emmy award-winning, The Dr. Oz Show kicked ... The segment features ...
(Date:9/23/2017)... 22, 2017 Janssen Biotech, Inc. (Janssen) announced ... from the U.S. Food and Drug Administration (FDA) for ... for the treatment of moderately to severely active rheumatoid ... data are needed to further evaluate the safety of ... RA. "We ...
(Date:9/19/2017)... , Sept. 19, 2017 HistoSonics, Inc., a venture-backed medical device company developing a ... targeted tissues, announced three leadership team developments today:   ... ... ... Veteran medical device executive Josh Stopek , ...
Breaking Medicine Technology: