Navigation Links
Oral Medicine Found To Remove Excess Iron in the Body

People suffering from severe chronic anemias and those with beta-thalassemia need frequent blood transfusions to remain healthy. // But the problem they frequently encounter is that due to transfusions there is an increase in the iron content in the body. This results in heart and liver failure.

The traditional treatment to remove excess iron is a time consuming process. Hence researchers studied deferasirox which is a new drug to treat patients suffering from chronic iron overload. The results of the study would be published in the month of May in the journal Blood. As of now the therapy to remove excess iron from the body is deferoxamine. This is administered for as long as the patient continues to receive blood transfusions, which, for many patients, can be for the rest of their lives. But the drug is very effective and safe.

The only drawback is that the drug has to be delivered by slow subcutaneous or intravenous infusion for eight to 12 hours a night over a period of five to seven days. On the other hand deferasirox is available in a once-daily, drinkable format, providing a promising alternative. Maria Domenica Cappellini, MD, of the University of Milan, Italy, and lead study author said that this reduces the strain on those patients especially children who require frequent blood transfusions help them to lead a normal and healthy life. She and her colleagues compared the efficacy and safety of the two drugs. Both children and adults participated in the study were diagnosed with chronic iron overload. People with beta-thalassemia, an inherited blood disorder, were selected for this study because complications of chronic iron overload have been best studied in those with this disease.

All participants continued receiving regular blood transfusions to treat beta-thalassemia throughout the year-long study. Participants were divided into two groups. In one group 290 patients received deferoxamine infusions five days a week and in t he second group 296 patients drank deferasirox dissolved in water each day before breakfast. Drug dosages were determined by each patient's liver iron concentration (LIC) level. The primary goal of the trial was to reduce LIC levels in those with high values and maintain LIC levels in those with low values. In the end of the study Deferasirox proved to be equally as effective as deferoxamine in patients receiving the highest doses of the drug. Deferasirox was generally well-tolerated with mild and common side effects such as skin rash and gastrointestional problems (abdominal pain, vomiting, diarrhea, and constipation).


'"/>




Related medicine news :

1. Nobel Prize for Medicine shared by Three scientists
2. Prince Charles lends support to Alternative Medicine
3. Healthy Medicine Or Harmful Intoxicant?
4. Medicines on the move
5. A surge in Lifestyle Medicine
6. Does Your Prescription Have An Inappropriate Medicine?
7. The Use Of Alternative Medicine On The Rise
8. New Medicine For Parkinson’s disease
9. Advent of New, More Effective and Personalized Medicines
10. Combing Hair More Effective Than OTC Medicine For Head Lice
11. Heart Patients Use Alternative Medicine
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... ... October 13, 2017 , ... ... Agile Software Development, has been awarded a contract by the Center for Medicare ... (BPA) aims to accelerate the enterprise use of Agile methodologies in a consistent ...
(Date:10/13/2017)... ... October 13, 2017 , ... “America On The Brink”: the Christian history ... The Brink” is the creation of published author, William Nowers. Captain Nowers and ... WWII veteran, he spent thirty years in the Navy. Following his career as ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... sleep apnea using cutting-edge Oventus O2Vent technology. As many as 18 ... characterized by frequent cessation in breathing. Oral appliances can offer significant relief to ...
(Date:10/12/2017)... ... 12, 2017 , ... The company has developed a suite ... regulatory authorities worldwide. From Children’s to Adults 50+, every formula has been developed ... , These products are also: Gluten Free, Non-GMO, Vegan, Soy Free, Non-Dairy*, ...
(Date:10/12/2017)... ... ... The American College of Medical Informatics (ACMI) will present the 2017 Morris F. ... AMIA’s Annual Symposium in Washington, D.C. AMIA’s Annual Symposium is taking place ... the field of medical informatics, this prestigious award is presented to an individual whose ...
Breaking Medicine News(10 mins):
(Date:10/11/2017)... , Oct. 11, 2017  Caris Life Sciences ... on fulfilling the promise of precision medicine, today announced ... joined Caris, Precision Oncology Alliance™ (POA) as its 17 ... centers, the St. Jude Crosson Cancer Institute will help ... the use of tumor profiling, making cancer treatment more ...
(Date:10/7/2017)... Texas , Oct. 6, 2017   Provista, ... with more than $100 billion in purchasing power, today ... news and information. The Newsroom is the ... and industry trends, infographics, expert bios, news releases, slideshows ... having access to a wealth of resources at their ...
(Date:10/2/2017)... Oct. 2, 2017 Diplomat Pharmacy, Inc. (NYSE: ... Software and Consulting, LLC , and named its founder ... based in Tennessee , will operate ... expands EnvoyHealth,s service offerings for health care partners to ... "In an interoperable world, technology ...
Breaking Medicine Technology: