Navigation Links
'Oncomodulin'- Path To Nerve Regeneration

Absence of nerve regeneration in injured nerve fibres in the mature central nervous system has always baffled scientists and researchers worldwide, //but researchers at Children’s Hospital Boston have discovered a naturally occurring growth factor Oncomodulin which could well be an answer to nerve damage diseases like glaucoma, tumors, trauma, spinal cord injury and even stroke.

Yuqin yin,MD, PhD and Larry Benowitz, PhD neuroscientists on the faculty of Harvard Medical School, have done studies on optic nerve, which connects retinal nerve cells to the brain,and is frequently used as a model in nerve regeneration studies.

In the studies on live rats with optic nerve injury on adding oncomodulin with other growth promoting factors the axon growth doubled. In another experiment oncomodulin was mixed with a sugar mannose and forskolin which helps the cell receptors to become sensitised to protein messengers and this combination was more potent than ciliary neurotrophic factor CNTF in the same conditions.

Oncomodulin has been known to scientists for more than two decades to be present in tumor cells and placenta before the pathbreaking discovery in the axons of the nerve cells in the eye.

The theory behind the discovery of oncomodulin is: On injury to the eye an inflammatory reaction occurred which stimulated macrophages which are immune cells to move into the axons and release an unidentified protein which causes nerve regeneration. But for oncomdulin to work it requires an agent which should increase cyclic AMP which initiates various cellular reactions and helps make the oncomodulin receptor available on the cell surface.

There is also a two pronged approach as put forth by Benowitz and postdoctoral fellow Dietmar Fischer, PhD in which natural inhibitors of axon growth are suppressed and growth factors are activated and thus this approach could give incredible results.

The use of oncomo dulin on humans is still in its infantile state but its discovery has embarked us on a hope filled journey to treat disabling and untreatable diseases like glaucoma and spinal cord injury.


Related medicine news :

1. Epilepsy Drug Helps Diabetic Nerve Damage
2. World’s First Nerve Stem Cells Produced
3. Children With Epilepsy Can Be Treated With Nerve Stimulation
4. FDA Approved Nerve-Stimulation Therapy Now Available In New York
5. Doctors Finish Mother-To-Son Nerve Surgery
6. Stem Cells From Hair Follicle To Repair Nerve Damage
7. Nerve regeneration for Spinal cord injuries
8. Novel Protein, Staufen2 Important In Maintenance Of Nerve Synapses
9. Dividing Nerve Cells Could Trigger Alzheimers Disease
10. Protein Found to Be Essential For Maintaining Nerve Health
11. Nerve Stimulator for Depression Though Not Effective Was Given Approval
Post Your Comments:

(Date:11/30/2015)... ... November 30, 2015 , ... ... The directory is specialized and only includes chiropractic clinics in the US. , ... and trustworthy alternative health practitioner when back pain sets in. When people are ...
(Date:11/30/2015)... Flint, Michigan (PRWEB) , ... November 30, 2015 ... ... a safe and fun atmosphere for Halloween festivities, the Word of Life Christian ... classic children’s board game, and featuring a giant 1.25 ton pile of candy ...
(Date:11/30/2015)... ... November 30, 2015 , ... During ... fundraising campaign to raise funds for its research, education, support, and advocacy efforts. ... organization’s annual funding. , The Mesothelioma Applied Research Foundation, which also goes by ...
(Date:11/30/2015)... (PRWEB) , ... November 30, 2015 , ... ... Catalyst continuing education course in Dallas, TX, on January 29 and 30, 2016. ... to improve the functions of their practices, to learn how to better succeed ...
(Date:11/30/2015)... (PRWEB) , ... November 30, 2015 , ... ... comparison chart and ingredient list of its hemorrhoid ointment to its website. , ... pain relief for people suffering from hemorrhoids. Adding the comparison chart and ingredient ...
Breaking Medicine News(10 mins):
(Date:11/30/2015)... 2015   Royal Philips (NYSE: PHG ... first MRI guided user interface and automatic scan parameter ... MR Conditional implants, such as knee and hip replacements, ... Society of North America Annual Meeting (RSNA) . The ... confidence of this growing patient population. ScanWise Implant adds ...
(Date:11/30/2015)... -- North America was valued at ... a CAGR of 7.6% from 2015 to 2020. --> ... in 2014, and is expected to grow at a CAGR of ... new Market Research Report "North America Cardiac Output Monitoring Devices Market ... care, others) - Analysis And Forecast To 2020", the cardiac output ...
(Date:11/30/2015)... KONG, Nov. 30, 2015 (HK$,000)For the Six Months Ended 30 September 2015 ... Income , 421,979 , 384,242 , ... , 34,719 , (18.3) Medical Insurance ... , 16.1 Medical Devices and Accessories Sales , ... Chinese Herbal Medicines Sales , 2,822 , ...
Breaking Medicine Technology: