Navigation Links
'Oncomodulin'- Path To Nerve Regeneration

Absence of nerve regeneration in injured nerve fibres in the mature central nervous system has always baffled scientists and researchers worldwide, //but researchers at Children’s Hospital Boston have discovered a naturally occurring growth factor Oncomodulin which could well be an answer to nerve damage diseases like glaucoma, tumors, trauma, spinal cord injury and even stroke.

Yuqin yin,MD, PhD and Larry Benowitz, PhD neuroscientists on the faculty of Harvard Medical School, have done studies on optic nerve, which connects retinal nerve cells to the brain,and is frequently used as a model in nerve regeneration studies.

In the studies on live rats with optic nerve injury on adding oncomodulin with other growth promoting factors the axon growth doubled. In another experiment oncomodulin was mixed with a sugar mannose and forskolin which helps the cell receptors to become sensitised to protein messengers and this combination was more potent than ciliary neurotrophic factor CNTF in the same conditions.

Oncomodulin has been known to scientists for more than two decades to be present in tumor cells and placenta before the pathbreaking discovery in the axons of the nerve cells in the eye.

The theory behind the discovery of oncomodulin is: On injury to the eye an inflammatory reaction occurred which stimulated macrophages which are immune cells to move into the axons and release an unidentified protein which causes nerve regeneration. But for oncomdulin to work it requires an agent which should increase cyclic AMP which initiates various cellular reactions and helps make the oncomodulin receptor available on the cell surface.

There is also a two pronged approach as put forth by Benowitz and postdoctoral fellow Dietmar Fischer, PhD in which natural inhibitors of axon growth are suppressed and growth factors are activated and thus this approach could give incredible results.

The use of oncomo dulin on humans is still in its infantile state but its discovery has embarked us on a hope filled journey to treat disabling and untreatable diseases like glaucoma and spinal cord injury.


'"/>




Related medicine news :

1. Epilepsy Drug Helps Diabetic Nerve Damage
2. World’s First Nerve Stem Cells Produced
3. Children With Epilepsy Can Be Treated With Nerve Stimulation
4. FDA Approved Nerve-Stimulation Therapy Now Available In New York
5. Doctors Finish Mother-To-Son Nerve Surgery
6. Stem Cells From Hair Follicle To Repair Nerve Damage
7. Nerve regeneration for Spinal cord injuries
8. Novel Protein, Staufen2 Important In Maintenance Of Nerve Synapses
9. Dividing Nerve Cells Could Trigger Alzheimers Disease
10. Protein Found to Be Essential For Maintaining Nerve Health
11. Nerve Stimulator for Depression Though Not Effective Was Given Approval
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... ... October 13, 2017 , ... Many families have long-term insurance ... care insurance companies have a waiver for care if the client has a cognitive ... the family pays for care, is often waived, so the benefits from their insurance ...
(Date:10/13/2017)... ... October 13, 2017 , ... Ellevate Network, the leading network ... advocate for action towards gender equality at their inaugural Summit in New York City ... and reached a social audience of over 3 million. To watch the Mobilize Women ...
(Date:10/13/2017)... ... ... Yisrayl Hawkins, Pastor and Overseer at The House of Yahweh, has released a ... books in the Holy Scriptures, Revelation. The Book of Revelation paints a picture of ... have tossed it off as mere rubbish, but Yisrayl Hawkins says that is because ...
(Date:10/13/2017)... ... October 13, 2017 , ... Coveros, a leader in agile ... a contract by the Center for Medicare and Medicaid Services (CMS). The Enterprise ... use of Agile methodologies in a consistent and high value manner across CMS ...
(Date:10/13/2017)... ... October 13, 2017 , ... “America On The Brink”: ... “America On The Brink” is the creation of published author, William Nowers. ... As a WWII veteran, he spent thirty years in the Navy. Following ...
Breaking Medicine News(10 mins):
(Date:10/4/2017)... , Oct. 4, 2017 OBP ... self-contained, illuminating medical devices, today announced regulatory approval ... Surveillance Agency (or Agência Nacional de Vigilância Sanitária ... single-use, cordless surgical retractor with integrated LED light ... access, illumination and exposure of a tissue pocket ...
(Date:10/2/2017)... Oct. 2, 2017  AllianceRx Walgreens Prime, the combined ... Walgreens and pharmacy benefit manager Prime Therapeutics LLC (Prime), ... which included the unveiling of new signage at its ... well as at a few other company-owned facilities across ... to patients, some of whom will begin to see ...
(Date:9/28/2017)... Sept. 28, 2017 Hill-Rom Holdings, Inc. (NYSE: ... conference call and webcast on Friday, November 3, 2017, ... and ending at approximately 8:30 a.m. (CDT) / 9:30 ... company,s 2017 financial performance and guidance for 2018, Hill-Rom ... to enhance operational performance, and long-range financial outlook through ...
Breaking Medicine Technology: