Navigation Links
'Oncomodulin'- Path To Nerve Regeneration

Absence of nerve regeneration in injured nerve fibres in the mature central nervous system has always baffled scientists and researchers worldwide, //but researchers at Children’s Hospital Boston have discovered a naturally occurring growth factor Oncomodulin which could well be an answer to nerve damage diseases like glaucoma, tumors, trauma, spinal cord injury and even stroke.

Yuqin yin,MD, PhD and Larry Benowitz, PhD neuroscientists on the faculty of Harvard Medical School, have done studies on optic nerve, which connects retinal nerve cells to the brain,and is frequently used as a model in nerve regeneration studies.

In the studies on live rats with optic nerve injury on adding oncomodulin with other growth promoting factors the axon growth doubled. In another experiment oncomodulin was mixed with a sugar mannose and forskolin which helps the cell receptors to become sensitised to protein messengers and this combination was more potent than ciliary neurotrophic factor CNTF in the same conditions.

Oncomodulin has been known to scientists for more than two decades to be present in tumor cells and placenta before the pathbreaking discovery in the axons of the nerve cells in the eye.

The theory behind the discovery of oncomodulin is: On injury to the eye an inflammatory reaction occurred which stimulated macrophages which are immune cells to move into the axons and release an unidentified protein which causes nerve regeneration. But for oncomdulin to work it requires an agent which should increase cyclic AMP which initiates various cellular reactions and helps make the oncomodulin receptor available on the cell surface.

There is also a two pronged approach as put forth by Benowitz and postdoctoral fellow Dietmar Fischer, PhD in which natural inhibitors of axon growth are suppressed and growth factors are activated and thus this approach could give incredible results.

The use of oncomo dulin on humans is still in its infantile state but its discovery has embarked us on a hope filled journey to treat disabling and untreatable diseases like glaucoma and spinal cord injury.


'"/>




Related medicine news :

1. Epilepsy Drug Helps Diabetic Nerve Damage
2. World’s First Nerve Stem Cells Produced
3. Children With Epilepsy Can Be Treated With Nerve Stimulation
4. FDA Approved Nerve-Stimulation Therapy Now Available In New York
5. Doctors Finish Mother-To-Son Nerve Surgery
6. Stem Cells From Hair Follicle To Repair Nerve Damage
7. Nerve regeneration for Spinal cord injuries
8. Novel Protein, Staufen2 Important In Maintenance Of Nerve Synapses
9. Dividing Nerve Cells Could Trigger Alzheimers Disease
10. Protein Found to Be Essential For Maintaining Nerve Health
11. Nerve Stimulator for Depression Though Not Effective Was Given Approval
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... ... 13, 2017 , ... As health professionals work to improve their approach to ... is doing more than filling out a survey; in many cases health professionals and ... in health care and research on the importance of active engagement with patients and ...
(Date:10/13/2017)... ... October 13, 2017 , ... ... PharmD ‘17, and Jennifer Huggins, PharmD ’17, along with clinical associate professor ... prevention of cardiovascular diseases during the 15th Annual Women’s Health Conference. The ...
(Date:10/13/2017)... ... October 13, 2017 , ... Ellevate Network, the leading ... to advocate for action towards gender equality at their inaugural Summit in New York ... globe, and reached a social audience of over 3 million. To watch the Mobilize ...
(Date:10/13/2017)... ... ... “The Journey: From the Mountains to the Mission Field”: the story of a ... “The Journey: From the Mountains to the Mission Field” is the creation of published ... all ages and currently teaches a class of ladies at her church, which she ...
(Date:10/12/2017)... Wis. (PRWEB) , ... October 12, 2017 , ... ... standard products to meet the demand of today’s consumer and regulatory authorities worldwide. ... of probiotic experts and tested to meet the highest standard. , These ...
Breaking Medicine News(10 mins):
(Date:10/2/2017)... Halo Labs announces the European launch of their new ... at MIBio 2017 in Cambridge, U.K on ... in biopharmaceutical samples with unprecedented speed and sensitivity while using far ... Membrane Imaging. ... particle analysis system ...
(Date:9/27/2017)... , Sept. 27, 2017  DarioHealth Corp. (NASDAQ: DRIO), a leading ... announced that its MyDario product is expected to appear on The Dr. ... The Dr. Oz Show airs in your area: http://www.doctoroz.com/page/where-watch-dr-oz-show ... The nine-time Emmy award-winning, The Dr. Oz Show ... The segment ...
(Date:9/22/2017)... -- AVACEN Medical (AVACEN) announced that its CE-Marked AVACEN ... with the widespread pain associated with fibromyalgia in the ... Essex, England commented, "I had difficulty ... sleep at all, tremendous pain, with every movement sending ... AVACEN 100] enough, how this has and is helping ...
Breaking Medicine Technology: