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Once-daily Nevirapine Has More Side-effects Than Twice-daily Dose

of rash leading to treatment interruption or discontinuation”, comment the investigators, adding, “the risk of liver complications is another lingering concern. For these reasons, once-daily nevirapine cannot be recommended at this time.”

The investigators do not, however, rule out the possibility of once-daily nevirapine use. They suggest that longer-term use of the drug could yield improved tolerance of higher concentrations of the drug. They write, “it is theoretically possible that the benefits of once-daily dosing can be achieved without excess toxicity by switching to once-daily nevirapine only after several months of twice-daily administration.”

Source-Bio-Bio Technoloy

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TAG: Once daily Nevirapine Has More Side effects Than Twice daily Dose

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