Navigation Links
Once-daily Nevirapine Has More Side-effects Than Twice-daily Dose

arable between the once-daily and twice-daily treated patients.

However, they also found that there was a trend for patients who were taking the drug once daily to be more likely to change therapy than those who were taking a twice-daily dose of nevirapine (29% versus 22%). They suggest that this could be because of a greater incidence of side-effects.

More patients experienced liver abnormalities in the once-daily group compared with twice-daily nevirapine (14% versus 8%; p=0.036). Also more patients in the once-daily group temporarily or permanently discontinued therapy because of rash (12% versus 7%).

Other smaller clinical trials were considered in the review. Each found that there was no statistically significant difference in the efficacy of once-daily and twice-daily nevirapine. In two of these studies there were also no differences in the frequency of adverse events between once and twice-daily regimens. A further study did, however, highlight a difference in frequency of adverse events between once- and twice-daily dosing of nevirapine.

This study involved 196 patients to investigate the safety and efficacy of switching from various twice-daily regimens (with or without nevirapine) to once-daily nevirapine (400mg), ddI (400mg) and tenofovir (300mg). In this study, adverse events leading to treatment discontinuation were more common in the once-daily group. After 48 weeks, three patients (4%) who continued twice-daily dosing stopped therapy versus twelve individuals (14%) who switched to once-daily dosing. The reasons for treatment discontinuation were: five cases of nevirapine-related hepatitis, two of acute pancreatitis, two of skin rash, two of dry mouth and one of peripheral neuropathy.

“Unfortunately, when compared with twice-daily dosing, antiretroviral regimens in which nevirapine is dosed at 400mg once daily immediately after a 2-week lead-in period are associated with an increased risk
'"/>




Page: 1 2 3

Related medicine news :

1. New Dietary Approach To Manage Kidney Stones
2. Approaching through Telemedicine benefits patients
3. Gel Offers A More Targeted Approach
4. New Cost Effective Approach To Promote Sun Protection
5. Treatment Of Brain Aneurysms By A New Non-Surgical Approach
6. A New Approach In Treatment Neurogenic Detrusor Overactivity In Children
7. A New Diagnostic Approach To Pediatric Interstitial Lung Disease
8. Lazy Eye Can Be Effectively Treated By New Approach
9. Novel Approach to Identify Protein Links with Genetic Disorder
10. NHS To Be Reformed By Using A Hybrid Approach
11. Two-In One Approach To Prevent Incontinence After Prolapse Surgery
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Once daily Nevirapine Has More Side effects Than Twice daily Dose

(Date:10/1/2014)... Phoseon Technology, the pioneer in developing ... the business worldwide. This rapid growth includes increased hiring ... manufacturing efforts. The company has experienced average annual growth ... expects this growth to continue in the future as ... adoption. , “We are very pleased that ...
(Date:10/1/2014)... 2014 Farmington Company today announced ... mission and visual identity helping brokers, consultants and ... them to create greater benefit communication synergies. They ... on empowering customers to better leverage Farmington Company’s ... jewel of the rebrand is the refreshed tagline: ...
(Date:10/1/2014)... A new genetic finding from Duke Medicine suggests that ... depression might also be hard-wired to gain weight when ... disease. , An estimated 13 percent of people, all ... and knowing this could help them reduce heart disease ... and stress management. , "Genetic susceptibility, psychosocial stress and ...
(Date:10/1/2014)... Kennebunkport, Maine (PRWEB) October 01, 2014 ... autoimmune disorders in the U.S., according to figures from ... Autoimmune Related Diseases Association (AARDA), and many of them ... higher chance of having undiagnosed celiac disease. Gluten ... helping raise awareness of undiagnosed celiac disease by publishing ...
(Date:10/1/2014)... 2014 Diet Doc understands that many of ... weight and their dieting attempts could be easily sabotaged by ... hormone diet treatments into their programs as a way ... fast and effective weight loss results, it also allows patients ... to maintain their weight for the future. , Earlier versions ...
Breaking Medicine News(10 mins):Health News:Phoseon Technology Continues to Drive Growth Worldwide 2Health News:Farmington Company Launches Rebrand and New Positioning 2Health News:Gene interacts with stress and leads to heart disease in some people 2Health News:Informative New Blog Series Underscores Link Between Celiac Disease and Other Autoimmune Disorders 2Health News:Informative New Blog Series Underscores Link Between Celiac Disease and Other Autoimmune Disorders 3Health News:Diet Doc Announces Their New Version of the Hormone Diet Plan to Target, Attack and Burn Fat Without Dangerous Side Effects 2Health News:Diet Doc Announces Their New Version of the Hormone Diet Plan to Target, Attack and Burn Fat Without Dangerous Side Effects 3Health News:Diet Doc Announces Their New Version of the Hormone Diet Plan to Target, Attack and Burn Fat Without Dangerous Side Effects 4
... cancer patients who exhibit limited lymph node involvement may ... neoadjuvant chemotherapy before a mastectomy, according to researchers from ... , The findings were reported today at the ... Radiology and Oncology. , "Radiation after surgery has been ...
... can affect practice behavior in inquiries about patient mood ... study led by University of Rochester Medical Center researchers. ... or attitudes, are loathe to broach sensitive topics such ... professor of psychiatry at the Medical Center and lead ...
... 24 As Senators Barack,Obama and John McCain arrive ... be greeted by AIDS activists from across the,country demanding ... his first 100 days in office., On Friday, ... the debate -,AIDS activists will hold a demonstration and ...
... Cooper University,Hospital in Camden, N.J., has agreed ... interest, to settle allegations that it defrauded ... settlement resolves allegations that the hospital improperly,increased ... reimbursement,from the federal health care program. In ...
... training in 60s, 70s wards off loss that weakens ... -- Strength training can help people build muscle mass to ... age until they reach 80, a new study says. , ... , The Ball State University study, sponsored by a ...
... The U.S. Pharmacopeial (USP) Convention is pleased to ... Material (CRM), Dextromethorphan Hydrobromide. USP recently became the ... Standardization accreditation as producer of chemical CRMs. ... new class of reference standard that ensures improved ...
Cached Medicine News:Health News:Cancer patients who receive neoadjuvant therapy followed by mastectomy may not need radiation 2Health News:Personality can hamper a physician's assessment of depression 2Health News:AIDS Activists from Across the Country Converge on Oxford, Mississippi, to Call on McCain and Obama to Commit to National AIDS Strategy 2Health News:New Jersey Hospital to Pay $3.85 Million to Resolve Allegations of Inflating Charges to Obtain Higher Medicare Reimbursement 2Health News:Boomers Should Add Muscle Before It's Too Late 2
(Date:10/1/2014)... and NEW YORK , October 1, 2014 /PRNewswire/ ... (CRO) and service provider for the medical industries, announced today the ... in New York City . genae Americas was ... is strategically centered in one of the highest concentrations of ... Philippe Kassab , President at genae Americas. "The expansion of ...
(Date:10/1/2014)... , Oct. 1, 2014  Varian Medical Systems (NYSE: ... report results for the fourth quarter of fiscal year ... October 22, 2014.  The news release will be followed ... 2:00 p.m. PT.  The news release and a link ... the company website at: www.varian.com/investor .  To access ...
(Date:10/1/2014)... , Oct. 1, 2014 Quantum ... scaling volume production of photoactive quantum dots for ... . While offering numerous advantages for solar power ... large quantities of quantum dots with which to ... kept them from commercial utilization and acceptance. The ...
Breaking Medicine Technology:genae Opens Offices in New York City 2Varian Medical Systems Schedules Fourth Quarter FY2014 News Release and Conference Call 2Quantum Materials Scaling Up Photoactive Quantum Dot Production for Solar Power Generation 2Quantum Materials Scaling Up Photoactive Quantum Dot Production for Solar Power Generation 3
... Medical School ,Contributing Editor , ,With over ... breast cancer undoubtedly qualifies as one of Americas ... develop early detection methods and more effective therapy ... true at the molecular level, where discoveries on ...
... located on the short arm of chromosome 6 (6p21.3), is ... HLA region is the human equivalent of the Major Histocompatibility ... that serve as the backbone of antigen presentation. The ... CD8+ T-cells, are expressed by genes located in the HLA-A, ...
Cached Medicine Technology:Breast Cancer and HER-2/neu: Diagnostic Tools for Targeted Therapy 2Breast Cancer and HER-2/neu: Diagnostic Tools for Targeted Therapy 3The Past, Present and Future of HLA Typing 2The Past, Present and Future of HLA Typing 3
The VasoSeal Low Profile device is designed for smaller sheath angiography procedures. VasoSeal Low Profile. Seal your arterial punctures with confidence....
... Fast-Cath, Maximum, Maximum Xtra, and ... line of standard and specialty hemostasis ... recognized as the premier hemostasis introducers ... electrophysiology procedures including angiography, angioplasty, stenting, ...
... to close arteriotomies with ease and ... a simple trigger actvated mechanism, requires ... sheath gently locks onto the target ... site before, during, and after the ...
The Prostar XL 10 is a suture mediated closure system. It can be used with 10F sheath. It has two 3-0 braided polyester sutures and also has the safety of guidewire....
Medicine Products: