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Older Men Have Similar Refracture Risk as Women

refracture risk comparable to or greater than an initial fracture risk of a 70- to 79-year-old woman.

For men, the absolute risk of a subsequent fracture was similar to that of women and equivalent to or greater than an initial fracture risk of a woman 10 years older. For example, a 60- to 69-year-old man's absolute refracture risk was equivalent to or greater than a 70- to 79-year-old woman's initial fracture risk and similar to the initial risk of a man at least 20 years older.

All fracture locations apart from rib (men) and ankle (women) resulted in increased subsequent fracture risk, with highest risks following hip and clinical vertebral fractures in younger men. In further analyses, femoral neck bone mineral density, age, and smoking were predictors of subsequent fracture in women and femoral neck bone mineral density, physical activity, and calcium intakes were predictors in men.

"The critical clinical relevance of these findings is that any incident low-trauma fracture is a signal for increased risk of all types of subsequent osteoporotic fracture, particularly in the next 5 to 10 years. Thus, virtually all low-trauma fractures indicate the clinical need for fracture preventive therapy, and given the early peak of refracture, such preventive treatment should not be delayed. The lack of consideration of osteoporosis and treatment initiatives by the medical profession and the public, particularly in relation to men, should be the focus of education initiatives," the researchers conclude.

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