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Obesity is Related to Lower Tuberculosis Risk

I (22.5 vs. 24.3) at the beginning of the study than those who did not. BMI outside the range of 18.5 to 23 decreased the active tuberculosis risk by 23.5 percent of the observed level.

Baseline BMI obesity at 25 or above was associated with a 30.1 percent decrease in risk, whereas BMI lower than 18.5 increased the risk by 6.6 percent, according to the authors. A higher average initial BMI was found in pulmonary-only cases than in extrapulmonary-only cases (22.3 vs. 24.1).

Obesity is associated with a lower risk of active pulmonary tuberculosis in the older population of Hong Kong, the authors conclude. The presence of such a strong but selective association across the whole spectrum of BMI could have major biological, clinical and/or epidemiological implications. Further studies are indicated to explore the underlying mechanisms, potential clinical utilities and possible epidemiological consequences.


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