Navigation Links
Obesity is Related to Lower Tuberculosis Risk

According to a study in the Archives of Internal Medicine journal, Obese or overweight Chinese individuals age 65 and older have a lower risk of developing tuberculosis than those at a normal weight.

Tuberculosis is commonly associated with poverty and undernutrition in both developed and developing countries. In addition, obesity is an increasing problem that is associated with a wide range of chronic degenerative conditions, notably, diabetes mellitus, a well-reported predisposing factor for active tuberculosis, according to background information in the article.

Few studies have systematically examined the effect of obesity and overweight on tuberculosis, especially in Asian populations.

Chi C. Leung, M.B.B.S., Tuberculosis and Chest Service, Hong Kong, and colleagues, studied 42,116 individuals 65 years or older enrolled in 18 health centers for elderly patients in Hong Kong. The patients were followed up from three months after enrollment in 2000 until December 31, 2005.

The body mass index (BMI) of each patient was measured at the beginning of the study. Those with a BMI of less than 18.5 were grouped as underweight, 18.5 to less than 23 as normal, 23 to less than 25 as at risk (for obesity), 25 to less than 30 as overweight, and 30 or higher as obese.

During the follow-up period, 477 cases of active tuberculosis were reported, 326 (68.3 percent) of which were confirmed using cultures of the bacteria involved. The average time between enrollment and notification of tuberculosis was 881 days.

There were 395 new cases (82.8 percent) and 82 retreatment cases (17.2 percent). Pulmonary [lung] involvement was found in 426 cases (89.3 percent) and extrapulmonary [outside the lung] involvement in 87 (18.2 percent), including 36 cases (7.5 percent) with both, the authors write.

Individuals who developed active tuberculosis were taller on average, but had a lower body weight and BM I (22.5 vs. 24.3) at the beginning of the study than those who did not. BMI outside the range of 18.5 to 23 decreased the active tuberculosis risk by 23.5 percent of the observed level.

Baseline BMI obesity at 25 or above was associated with a 30.1 percent decrease in risk, whereas BMI lower than 18.5 increased the risk by 6.6 percent, according to the authors. A higher average initial BMI was found in pulmonary-only cases than in extrapulmonary-only cases (22.3 vs. 24.1).

Obesity is associated with a lower risk of active pulmonary tuberculosis in the older population of Hong Kong, the authors conclude. The presence of such a strong but selective association across the whole spectrum of BMI could have major biological, clinical and/or epidemiological implications. Further studies are indicated to explore the underlying mechanisms, potential clinical utilities and possible epidemiological consequences.


'"/>




Related medicine news :

1. Lean Protein Could Be Key to Obesity Drugs
2. Obesity raises IVF miscarriage risk
3. Obesity a risk for pancreatic cancer
4. Obesity shortens lifespan
5. Is Obesity a risk factor?
6. Obesity a global problem
7. Obesity increases health costs
8. Obesity in children a risk factor for diabetes
9. Decrease of Hunger Hormone after Obesity Surgery
10. Obesity risk for immobilized adults
11. Obesity risk can be reduced by eating breakfast regularly
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/24/2017)... ... ... My T Chai, a South African company that creates a number of ... a popular website specializing in sales of nutritional products. , Chai tea is ... It spread across Asia and Africa quickly, and today recipes vary from region to ...
(Date:4/24/2017)... ... April 24, 2017 , ... ... expected to be diagnosed globally; approximately 25,000 of them will be malignant.(1) As ... use of this type of healthcare model in the diagnosis and treatment of ...
(Date:4/24/2017)... , ... April 24, 2017 , ... As a former ... a thousand words. The good news for single women is that she put all ... is available on April 25th. Joan's insight, personal experiences and sparkling sense of humor ...
(Date:4/24/2017)... ... April 24, 2017 , ... A new global study of ... student well-being has seriously declined. "When disenfranchised youth from the heart of our ... State to turn the historic multi-ethnic and multi-religious powerhouses of the Middle East ...
(Date:4/24/2017)... ... April 24, 2017 , ... Miami ... attending the 2017 Oral Reconstruction Foundation’s 2017 Symposium on Tissue Regeneration and Implant ... will present its annual Global Symposium at the Fontainebleau Hotel located in Miami ...
Breaking Medicine News(10 mins):
(Date:4/19/2017)... , April 19, 2017  IRIDEX Corporation (Nasdaq: ... release financial results for the first quarter 2017 after ... The Company,s management team will host a corresponding conference ... ET. Investors interested in listening to the ... for domestic callers or (703) 326-3030 for international callers, ...
(Date:4/19/2017)... DALLAS , April 19, 2017  Vanderbilt ... the first patients in Nashville , ... the Lower Esophageal Sphincter Stimulation for GERD (LESS GERD) ... designed to provide long-term reflux control by restoring normal ... affects nearly 65 million people in the ...
(Date:4/19/2017)... -- Companion animal vaccines are ... such as canine, avian and feline. ... as Attenuated Live Vaccines, Conjugate Vaccines, Inactivated Vaccines, ... Vaccines. Attenuated live vaccines are derived from disease-causing ... been weakend under laboratory conditions. Conjugate vaccines are ...
Breaking Medicine Technology: