Navigation Links
Obesity Pill Zimulti Increases Depression, Suicidal Thoughts

Boffins conducting clinical trials of obesity pill Zimulti found that it increases suicidal thoughts in patients. Reviewers for the US Food and Drug Administration (FDA) said that though the 20-milligram dose of the drug, led to significant weight loss over one year when taken with a low-calorie diet, there was still cause for concern over depression and a high drop-out rate in clinical trials.

"(Zimulti) was shown to reduce body weight by approximately 5% relative to diet alone during trials of more than 6000 moderately overweight and obese subjects", the New Scientist quoted the FDA reviewers, as saying.

Known generically as rimonabant, the drug is already sold in 18 countries under the name Acomplia. "We remain concerned about rimonabant's adverse event profile, specifically adverse psychiatric reactions," an FDA staff summary said.

The trials showed that in people who took the drug were twice as likely to develop depression than those who received a placebo. However, the drug's manufacturer Sanofi-Aventis insisted that though more rimonabant patients reported suicidal thoughts, the drug's benefits "clearly outweigh the defined risks that are manageable in clinical practice".

Rimonabant works by blocking food craving signals in the brain. Sanofi, a French drug maker, developed the drug to target the brain receptors that trigger intense hunger after marijuana use.


'"/>




Page: 1

Related medicine news :

1. Lean Protein Could Be Key to Obesity Drugs
2. Obesity raises IVF miscarriage risk
3. Obesity a risk for pancreatic cancer
4. Obesity shortens lifespan
5. Is Obesity a risk factor?
6. Obesity a global problem
7. Obesity increases health costs
8. Obesity in children a risk factor for diabetes
9. Decrease of Hunger Hormone after Obesity Surgery
10. Obesity risk for immobilized adults
11. Obesity risk can be reduced by eating breakfast regularly
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/26/2017)... ... May 26, 2017 , ... The Radiology Business ... focus on current legislative activity and the latest regulatory concerns impacting RBMA members. ... Sept. 10, and will continue through Monday, Sept. 11, at the Ritz-Carlton, Tysons ...
(Date:5/26/2017)... ... May 26, 2017 , ... Boar’s Head ... bold recipes for Memorial Day entertaining that are sure to satisfy your guests’ ... fresh sliced meats and cheeses featured in these refreshingly balanced recipes are packed ...
(Date:5/26/2017)... ... ... Yisrayl Hawkins, Pastor and Overseer at The House of Yahweh in Abilene, ... Agreements being discussed by President Donald Trump and the rest of the world. Donald ... up peace talks in the continuous battle between Israel and Palestine. The world’s eyes ...
(Date:5/26/2017)... ... ... “When the Stars Lead Home”: a poignant story of loss, determination, and perseverance. “When ... avid reader who lives in the Pacific Northwest with her husband, daughter, two dogs, ... She couldn’t be more grateful. , Twelve-year old Tizzy could not believe how quickly ...
(Date:5/26/2017)... ... May 26, 2017 , ... “Cactus Jack: Against All Odds”: the ... others. “Cactus Jack: Against All Odds” is the creation of published author, Walter ... is married to Jack Carlisle’s third child Jane. Walter. Walter and Jane have ...
Breaking Medicine News(10 mins):
(Date:5/6/2017)... Texas , May 5, 2017   Provista , ... with more than 200,000 customers, today announced Jim Cunniff ... a wealth of executive and business experience to Provista, including ... compounding pharmacy in California . He assumed ... "Jim is a great fit for Provista," says ...
(Date:5/6/2017)... 5, 2017  Hill-Rom Holdings, Inc. (NYSE: HRC), has ... square feet to its Welch Allyn campus. ... to bring more than 100 new jobs to ... has maintained a significant presence for more than 100 ... positions, a large portion of which will be R&D ...
(Date:5/4/2017)... , May 4, 2017  A recent ... Control, Ultraviolet-C light as a means ... SmartUVC,s ability to reduce bioburden on anesthesia workstations. ... reduction on high-touch, complex medical equipment surfaces contaminated ... infections. "This study further validates the ...
Breaking Medicine Technology: