Navigation Links
Obesity Pill Zimulti Increases Depression, Suicidal Thoughts

Boffins conducting clinical trials of obesity pill Zimulti found that it increases suicidal thoughts in patients. Reviewers for the US Food and Drug Administration (FDA) said that though the 20-milligram dose of the drug, led to significant weight loss over one year when taken with a low-calorie diet, there was still cause for concern over depression and a high drop-out rate in clinical trials.

"(Zimulti) was shown to reduce body weight by approximately 5% relative to diet alone during trials of more than 6000 moderately overweight and obese subjects", the New Scientist quoted the FDA reviewers, as saying.

Known generically as rimonabant, the drug is already sold in 18 countries under the name Acomplia. "We remain concerned about rimonabant's adverse event profile, specifically adverse psychiatric reactions," an FDA staff summary said.

The trials showed that in people who took the drug were twice as likely to develop depression than those who received a placebo. However, the drug's manufacturer Sanofi-Aventis insisted that though more rimonabant patients reported suicidal thoughts, the drug's benefits "clearly outweigh the defined risks that are manageable in clinical practice".

Rimonabant works by blocking food craving signals in the brain. Sanofi, a French drug maker, developed the drug to target the brain receptors that trigger intense hunger after marijuana use.


'"/>




Page: 1

Related medicine news :

1. Lean Protein Could Be Key to Obesity Drugs
2. Obesity raises IVF miscarriage risk
3. Obesity a risk for pancreatic cancer
4. Obesity shortens lifespan
5. Is Obesity a risk factor?
6. Obesity a global problem
7. Obesity increases health costs
8. Obesity in children a risk factor for diabetes
9. Decrease of Hunger Hormone after Obesity Surgery
10. Obesity risk for immobilized adults
11. Obesity risk can be reduced by eating breakfast regularly
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:7/25/2017)... ... July 25, 2017 , ... “Now Hiring!” is a popular ... The company has achieved record-breaking sales for over 30 consecutive years and now ... months. , The upcoming year offers excitement and growth at HDIS, following the company’s ...
(Date:7/25/2017)... ... July 25, 2017 , ... Creative ... their partnership to provide the Pharmacist eCare Plan to Computer-Rx pharmacies ... country with the ability to develop the Pharmacist eCare Plan, a shared document ...
(Date:7/25/2017)... ... July 25, 2017 , ... Dr. Donna Bergman, professor ... co-authored and published an article in the medical science journal Physical Medicine and ... the article and the research that helped produce it, were written and conducted ...
(Date:7/25/2017)... (PRWEB) , ... July 25, 2017 , ... Facing medical ... father Ezra Clark is taking advantage of a new benefit for employees that is ... means a lot that the company supports me and other employees as new parents. ...
(Date:7/24/2017)... ... July 24, 2017 , ... Engineers at the University ... it produces the same kind of electrical energy that the body uses. , ... moving electrons. This flow of electrons out of the battery is generated by moving ...
Breaking Medicine News(10 mins):
(Date:7/13/2017)... 13, 2017  Centurion Medical Products, a leader in medical product ... fecal impaction removal device for hospice patient care. ... Centurion Medical Products ... Patient pain management and emotional comfort are part ... alleviate patient pain while preventing unneeded emergency department admission due to ...
(Date:7/12/2017)... -- Eli Lilly and Company (NYSE: LLY ) has ... pending patent litigation in the U.S. District Court for the ... Cialis ® (tadalafil) unit dose patent. This patent was ... of the agreement, Cialis exclusivity is now expected to end ... unit dose patent for Cialis is valid and infringed by ...
(Date:7/11/2017)... 11, 2017  Sysmex America, Inc., a leading ... equipment as well as middleware information systems technology, ... make quality assurance easier and more risk free ... known for the innovation that it delivers to ... quality assurance processes to a new level with ...
Breaking Medicine Technology: