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Obesity Could Be Linked to Mother's Early Puberty

Those born to mothers who attained early puberty tend to be overweight as children, say UK researchers.//

Such children could also grow rapidly. And this faster growth pattern is also linked to obesity in adulthood. The findings follow a study of 6,000 children by a Cambridge university team.

It is already known that age at which a girl has her first period - or reaches "menarche" - is largely inherited.

And women who start their periods early are at increased risk of obesity in later life, and are likely to be overweight even before puberty.

Knowing that rapid infancy weight gain, early puberty and obesity run together in families may help us identify which children to best target our efforts at right from birth, says Dr Ken Ong, lead researcher.

In the latest study, mothers who began their periods before age 11 were five times more likely to be obese than mothers who had their first period after the age of 15.

Children of mothers who had early first periods were taller by the age of nine and weighed more. Girls were also more likely to start their periods before the age of 11.

Those whose mothers had their first period under the age of 11 were three times more likely to be obese than those who started their periods after the age of 15.

The researchers also looked in more detail at growth measurements from birth to nine years in 900 children, and found that mothers' age at first period was associated with faster growth in weight and height in children up until the age of two years.

Children who have a fast growth pattern tend to start puberty earlier, but stop growing sooner - so they may not be particularly tall as adults.

"Beyond links to early puberty, most importantly this growth pattern appears to lead to an increased risk of obesity that lasts from childhood through to adult life."

He added there could be a genetic l ink - perhaps related to appetite - or that the findings may be explained by feeding behaviours or patterns that run in families.

He added that parents should be encouraged to breastfeed rather than bottle-feed.

The team are also beginning a study to look at trying to avoid excessive calorie consumption in babies who are formula fed.

Dr Tabitha Randell, consultant paediatric endocrinologist at University Hospital Nottingham, said the big point was that heavier mothers had heavier children.

"Age at menarche is strongly related to your weight and it's well recognised that it's getting earlier and earlier." But she said that environmental factors were just as important as genetics.

"It would be very interesting to have a look at the effect of breastfeeding.

"It sets up feeding patterns. You lay down your number of fat cells in the first couple of years of life," she said.

The findings could help identify children at risk of weight problems early on, a report in the Public Library of Science Medicine (PLOS) concludes.
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