Navigation Links
Obesity, a Risk Factor for Developing Multiple Myeloma

Researchers have found that obese persons are at higher risk as compared to lean person to develop multiple myeloma.

Multiple myeloma or Kahler's disease is a type of cancer of plasma cells which are immune system cells in bone marrow that produce antibodies. Its prognosis, despite therapy, is generally poor, and treatment may involve chemotherapy and stem cell transplant.

The joint study was conducted by a team of researchers led by Brenda M. Birmann at Brigham and Womens Hospital, Harvard Medical School, and Harvard School of Public Health.

As part of the study, researchers analysed data of over 100,000 participants in the on-going Nurses Health Study and Health Professionals Follow-up Study.

The Brigham and Womens Hospital-based Nurses Health Study followed the health of female registered nurses since 1976, and the Health Professionals Follow-up Study, based at Harvard School of Public Health, followed males from several health professions since 1986.

The studies recorded height, weight and physical activity for each person enrolled, as well as diet, medications, smoking habits and other health behaviours, which was updated every two to four years.

Researchers found that of the 136,623 participants, who qualified for the study protocol, 215 cases had multiple myeloma.

The association between BMI and multiple myeloma was strongest among men with a BMI of 30 or more. The effect was less pronounced among overweight or obese women, yet those women also had an increased risk.

Researchers explained that previous research has identified possible biological links between obesity and multiple myeloma. For example, adipocytes, cells found in fat tissue, produce a cell signal, called interleukin-6 (IL-6), which promotes the immune systems inflammation response. In obese people, this can cause an overproduction of IL-6, which in turn creates a cellular enviro nment that sustains multiple myeloma.

"The IL-6 chemical pathway is one possible way obesity could influence the risk of developing diseases like cancer or cardiovascular disease, but the answer might also lie in other relationships between obesity and cancer," Birmann said.

The findings of the study were published in the July issue of Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research.


'"/>




Related medicine news :

1. Obesity, diabetes in pregnant women affects babies
2. Strong Link Between Obesity, Diabetes And Periodontal Disease
3. Government Initiatives To Halt Child Obesity, Needs Clarity Of Purpose
4. Obesity, a Reflector of Mental Health – Study Find
5. Agricultural Subsidies Responsible For Obesity, Says Expert
6. Under-Elevens Hurtle Towards Obesity, British MPs Call for Action
7. Hypertension, Diabetes and Obesity, a Deadly Trio
8. 20-year Study Shows Significant Rise in Childhood Obesity, Especially Among Girls
9. Obesity, High Blood Pressure on the Rise Among College Students
10. Risk Factors for vision problems in Diabetes
11. Age-Related Macular Degeneration - Risk Factors
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/13/2016)... ... February 13, 2016 , ... In the early or “honeymoon” stage ... to perfection, go out of their way to be romantic, and may exaggerate a ... look at any online dating profile. , A recent study from Queendom.com ...
(Date:2/12/2016)... Opelousas, LA (PRWEB) , ... February 12, 2016 , ... ... of St. Landry and Evangeline Parishes. The purpose of these scholarships is to ... to encourage those individuals to seek employment within these two parishes. , “We ...
(Date:2/12/2016)... ... February 12, 2016 , ... Fixed Dose Combination Drug Development: ... EST, http://www.fdanews.com/fixeddosecombination , Fixed dose combination products are ... attention from all stakeholders in the development of new chemical entities. , However, ...
(Date:2/12/2016)... ... 2016 , ... T.E.N., a technology and information security executive ... Awards 2016. Finalists and winners of the ISE® Awards for both Executive and ... Gala on March 15, 2016 at the Westin Peachtree Plaza, Atlanta. , ...
(Date:2/12/2016)... ... 12, 2016 , ... Fisher House Foundation Chairman and CEO Kenneth Fisher joined ... Support Alliance president Scott Bensing, and Peggy Kearns Director, VA Southern Nevada Healthcare System ... This will be the first Fisher House in Nevada, and will provide free ...
Breaking Medicine News(10 mins):
(Date:2/11/2016)... , Feb. 11, 2016 Potrero Medical, Inc., the ... to announce the appointment of George M. Rapier, III ... San Antonio, TX , WellMed is one of the ... patients and HMO members in Texas ... 1990 out of his own internal medicine practice, he has ...
(Date:2/11/2016)... -- MiMedx Group, Inc. (NASDAQ: MDXG ), the leading ... birth tissues, human skin and bone, and patent-protected processes ... and therapies, announced today that it will present at ... New York , NY.  Parker H. ... , Chief Financial Officer and Chris Cashman , ...
(Date:2/11/2016)...  AfterPill.com is reporting that this week,s Centers for ... women who are at risk of unintended pregnancy impacts ... raises the risks of unprotected sex in particular.  ... to the Guttmacher Institute, there are 43 million women ... who have sex without the intention of becoming pregnant.  ...
Breaking Medicine Technology: