Navigation Links
Now, 'virtual' Mouse Brains Available on the Net

A multi-institutional consortium that includes Duke University has created high resolution, three-dimentional microscopic images of tiny mouse brains, which unveil every layer of the organ.

The researchers could materialise this task by extending the capabilities of conventional magnetic resonance imaging.

"These images can be more than 100,000 times higher resolution than a clinical MRI scan," said G. Allan Johnson, Duke's Charles E. Putman Distinguished Professor of radiology and professor of biomedical engineering and physics, whose innovation has been reported in the journal NeuroImage.

The images available at http: www.civm.duhs.duke.edu/ show two different mouse brains-one from a normal animal and the other from a rodent missing a gene linked to mental abnormalities. These pictures show two colour-coded brain structures, the ventricles and hippocampus, showing different volumes resulting from specific genetic differences.

National Center for Research Resources is funding for the development of the new imaging technologies that are being shared by six institutions that form the Mouse Bioinformatics Research Network (MBIRN), including Duke University.

The consortium has developed the computer infrastructure to collect a rapidly growing library of 3-D mouse brain data, and make all the data available on the web http: tinyurl.com/3cgj6z. Its goal is to use mouse brains as surrogates for human brains to study the connections between genes and brain structure.

Investigators from all over the world are sending their models to Duke, where the 3-D images are acquired in a standardized fashion and made available via high speed web connections.

"The specimen is still actually in the skull. It hasn't been cut by a knife. It has not been dehydrated and distorted as it would be in conventional histological techniques," Johnson said.

The researcher says that MRI scanning is quicker and costs less than conventional histology, and it enables researchers to study the entire brain.

"We have the ability to highlight soft tissue differences with extraordinary clarity," Johnson said.


'"/>




Related medicine news :

1. Mouse Allergen Found In Homes Could Trigger Asthma In Kids
2. Researchers Develop Mouse Model Of Brain Tumor
3. German Scientists Create Stem Cells From Mouse Testes
4. Mouse Models To Determine The Cause Of Aggressive Leukemia
5. Mouse Model Beneficial to Study of Head and Neck Cancer
6. Scientists Discover New RNAs in Mouse Testicles
7. Scientists Isolate Leukemia Stem Cells in Mouse Model
8. Mouse Model Demonstrates Immune System Reaction In Chlamydia Infection
9. Mouse Gene With Gene Stutter Will Help Leukemia Research
10. Rett Syndrome Reversed in Genetic Mouse Model
11. Treatment Extends Survival in Mouse Model of Spinal Muscular Atrophy
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/11/2016)... ... ... Be Well Medical Group (Be Well) is pleased to announce ... South Columbus St, Suite 201, Alexandria, VA. Be Well Medical Group is a concierge ... of their homes, offices or at the practices’ local office. It is also one ...
(Date:2/11/2016)... ... ... The book, “Computers Should Just Work!”, provides a basic, non-techie education on how ... signing a contract and how to spot an incompetent or dishonest IT person before ... and technology, it’s more important than ever to make sure the company you outsource ...
(Date:2/10/2016)... ... 10, 2016 , ... Sherly Sulaiman, certified clinical hypnotherapist and ... sessions to help Los Angeles-area actors cope with rejection, improve their auditions, and ... as “Mindfulness for Actors and Artists,” has been featured in Daily Actor ...
(Date:2/10/2016)... , ... February 10, 2016 , ... ... is unveiling its revolutionary new 2.0 version at the International Roofing Expo in ... the power of the world's most advanced weather technology in the hands of ...
(Date:2/10/2016)... ... 2016 , ... The Wickman Agency in Garland, TX has ... community. Pledging to select a new beneficiary every 60 days, the agency will ... is to bring community awareness to important local causes by forming campaigns which ...
Breaking Medicine News(10 mins):
(Date:2/10/2016)... A Worldwide Clinical Trials expert will ... Victoria Park Plaza in London , 24-25 ... and future advances for late phase research on Wednesday, 24 ... , associate director of project management at Worldwide, will focus ... regulations and standards in late phase research. ...
(Date:2/10/2016)... 10, 2016  The Baylor University ... an in-kind gift from Christie Medical ... vein finder for the nursing school simulation ... they learn how to start an IV ... technique. ...
(Date:2/10/2016)... ATLANTA , Feb. 10, 2016  LexisNexis® ... and technology, today announced the launch of ... analytics solution that helps improve and optimize the ... evaluation of performance using severity-adjusted scores. By measuring ... a critical solution to deliver better outcomes, improve ...
Breaking Medicine Technology: