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Novel test for diagnosis of breast cancer

According to some Swiss scientists, a new kind of breast cancer test, which could save several women from needless chemotherapy, is reliable.//

Already, doctors have been using core needle biopsy to sample suspect breast tissue for microscopic examination.

This new test involves the study of gene patterns in the sample. This may help in detecting more aggressive cancers that need intensive treatment. But the test has very little proof.

Till date, the mammogram screening is the most popular and dependable test. But it is painful, fairly expensive and the results may take up to a week’s time.

The Swiss research published in Breast Cancer Research confirms its worth. The most popular and reliable breast cancer test remains the mammogram screening. But it can be painful, relatively costly and results can take up to a week.

The team from University Hospital Basel found gene expression profiling of needle biopsy samples gave an accurate picture of entire breast tumors, despite only sampling very tiny parts of the cancers.

This information could then be used to distinguish which cancers are aggressive and need intensive treatment, such as intensive chemotherapy after surgery, and which tumors have little chance of returning after being removed surgically.

According to the Swiss study, core needle biopsy is a better method than surgical cutting, to get the breast tissue for gene profiling. The core needle biopsy is not only, less harmful but also gives a better indication of the gene patterns present in the cancer tissue. This method seemed to activate the expression of genes involved in wound healing and tumor invasion and spread. Any successive surgical sample taken would have a modified gene expression profile.

A recent study proves the above-mentioned statement. It involves 22 women with breast cancer. It was seen that the expression of 4 specific genes known to be involved in breast
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