Navigation Links
Novel protein found to enhance effect of Vitamin E and suppress prostate cancer

Researchers have identified a protein that disrupts an important signaling pathway in prostate cancer cells, thereby suppressing the tumor. The protein also enhances the retention of Vitamin E // that limits the proliferation of cancer cells.

The researchers of the present study are the first to describe the role of a protein known as alpha tocopherol associated protein or TAP in prostate cancer. Expression levels of TAP are significantly lower in prostate cancer than in a normal prostate.

Restoration of the levels of the protein in individuals with prostate cancer can be extended to have a therapeutic effect. The approach however would be technically very difficult. Therefore, the present practical solution is to investigate whether specific substances can increase the expression of TAP.

TAP is a binding protein that performs important cellular functions. The high levels of TAP in normal prostate cells suggest that TAP facilitates the transport of vitamin E into prostate tissue and helps retain high concentrations of the vitamin in the cells.

In prostate cancer cells, the researchers showed for the first time that TAP supports the retention of vitamin E. It was also found that TAP increases vitamin E's capacity to control the rapid growth of the cancer cells.

A cell can send messages from its surface to the nucleus through a set of chemical reactions known as a signaling pathway. The disruption of such a pathway by TAP has been found to suppress cancer cell growth. The pathway involves two proteins, phosphatidylinositol 3-kinase and constitutively active Akt, both of which play an important role in the initiation and progression of prostate cancer.

If research continues to show the important role of TAP, we could use TAP expression levels to better assess and predict the aggressiveness of the cancer. We may even be able to use TAP levels to predict whether a patient will respond to treatment.


'"/>




Page: 1

Related medicine news :

1. Novel "CYCLOSPORINE CAPSULE FORMULATION" to be launched
2. Novel biopsy technique for prostate cancer
3. Novel computer model for breast cancer
4. Novel research on liver cancer
5. Novel way to fight cancer
6. Novel test for bowel cancer
7. Novel Anti-Neutrophilic Effect produced by Salmeterol in mild asthma patients
8. Novel Therapy for Chronic Problem
9. Blood Sugar Kept In Control By Novel Protein
10. Novel antibiotic dressing developed for improved wound healing
11. United Kingdom Is Lagging In Novelty In The Field Of Pharmaceuticals
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/24/2017)... ... May 24, 2017 , ... ... and choosing the most appropriate instruments for research and understanding the basic principles ... This webinar will focus on innovations in stereo microscopy for brightfield and fluorescence ...
(Date:5/24/2017)... ... May 24, 2017 , ... Altec Products, Inc., a leader in ... a one-day technology conference in San Diego, CA. , At nVerge 2017, Altec ... fully utilize and enhance their Sage ERP solutions by providing improved visibility and control ...
(Date:5/24/2017)... ... May 24, 2017 , ... Drs. Nicholas ... who have now spent 10 years as clinical instructors for the reputable Full ... of Dentistry. Through the program, private practitioners receive cutting-edge clinical training and learn ...
(Date:5/24/2017)... ... May 24, 2017 , ... Patients who want to receive cosmetic dentistry procedures ... Dr. Joseph Bedich for a consultation, with or without a referral. Dr. Bedich enjoys ... functionality. , Dr. Bedich offers a variety of cosmetic dentistry services at ...
(Date:5/24/2017)... ... 24, 2017 , ... Myers Jackson is well known for auctioning homes that ... homes anywhere on the planet. The luxury home market is alive and well and ... A quick search of “11 Spyglass Hill Auction will enlighten you on the dynamics ...
Breaking Medicine News(10 mins):
(Date:5/9/2017)... 9, 2017  Oramed Pharmaceuticals Inc. (NASDAQ: ... pharmaceutical company focused on the development of oral ... Intellectual Property Office has granted Oramed a patent ... Exenatide". The patent covers Oramed,s invention of an ... is an incretin hormone that stimulates the secretion ...
(Date:5/6/2017)... Provista , a proven leader in the supply chain industry ... Jim Cunniff as the company,s new president and CEO. ... Provista, including most recently serving as the president and CEO ... He assumed his new role with Provista on May 1, ... says Jody Hatcher , president, Sourcing and Collaboration Services ...
(Date:5/4/2017)... 2017  A recent study published in the ... light as a means of disinfection anesthesia workstations ... bioburden on anesthesia workstations. In the study, UVC ... medical equipment surfaces contaminated with three (3) organisms ... study further validates the body of literature supporting ...
Breaking Medicine Technology: