Navigation Links
Novel genetic blood test

An international team of researchers is developing a new genetic blood test that allows a much closer match between donors and recipients//. The Bloodchip gives more details in the result than the existing tests. The current tests look for blood types while the Bloodchip looks for DNA “signatures”.

A spokeswoman for the National Blood Service, which is helping develop the test, said, “It could be "a lifesaver" for those needing regular transfusions. It is hoped the test could be of particular benefit to people with blood conditions such as sickle cell anaemia, haemophilia, thalassaemias and leukaemia.”

The developers of Biochip warn that patients with these conditions, who require routine blood transfusions, can develop life-threatening side effects on receiving not a properly matched blood.

3,000 healthy blood samples are being tested with Biochip as a "proof of principle". The results reveal its accuracy compared to the current tests. This was done with the intention of getting European health and safety approval.

The existing serological tests identify the blood group; A, B, AB or O and the rhesus antigen, thus Rh positive or negative. Whereas, the Biochip test identifies nearly 9 other possible differences in the blood, like the Duffy system - blood can be Duffy A or Duffy B.

When differences in each system are considered, the test could detect around 116 blood type DNA "signatures" Thee DNA extracted from blood samples are tested on glass microscopic slides. Chemicals are added to the DNA on the slide, resulting in reaction that gives out fluorescent colours. A scanner in which the slide is placed determines blood types.

Professor Neil Avent, director of University of West England's Centre for Research in Biomedicine who has been involved in the research, said: "Blood transfusions are inherently safe. But with the compatibility between the donor and the recipient being tested using serological tec hniques, there is a significant section of the population that suffer serious illness and side effects after receiving multiple transfusions of blood that is not a perfect match."

"These patients over time develop antibodies that reject imperfectly matched blood transfusions, a process known as alloimmunisation, which can lead to serious illness and life-threatening side effects." "Bloodchip has been developed with these communities in mind."

Professor Marion Scott, national director of research at the UK National Blood Service, said: "The Bloodchip test will literally be a lifesaver for those who suffer from illnesses that require multiple blood transfusions such as haemophilia, sickle cell disease and thalassaemias.

"Sickle cell disease and thalassaemias are particularly prevalent in those from African, Caribbean, Eastern Mediterranean, Middle East and Asian backgrounds and both can be life-threatening.

"The Bloodchip test will be of enormous benefit in ensuring those with these disorders receive perfectly matched blood to enable them to better manage their conditions."

A consortium called Bloodgen has been formed by scientists from the UK, Germany, Sweden, Spain, the Czech Republic and the Netherlands, to develop the test . Progenika Biopharma in Spain will manufacture the Biochip.

Related medicine news :

2. Novel biopsy technique for prostate cancer
3. Novel computer model for breast cancer
4. Novel research on liver cancer
5. Novel way to fight cancer
6. Novel test for bowel cancer
7. Novel Anti-Neutrophilic Effect produced by Salmeterol in mild asthma patients
8. Novel Therapy for Chronic Problem
9. Blood Sugar Kept In Control By Novel Protein
10. Novel antibiotic dressing developed for improved wound healing
11. United Kingdom Is Lagging In Novelty In The Field Of Pharmaceuticals
Post Your Comments:

(Date:11/25/2015)... CA (PRWEB) , ... November 25, 2015 , ... According ... Vinci surgical robot is being more and more widely heralded as a breakthrough for ... da Vinci method has over traditional laparoscopic surgery is that it can greatly reduce ...
(Date:11/25/2015)... Boca Raton, Florida (PRWEB) , ... November 25, ... ... on-site diagnostic testing for physicians and athletic programs, launches new Wimbledon Athletics ... the importance of testing young athletes for unsuspected cardiac abnormalities. About 2,000 people ...
(Date:11/25/2015)... (PRWEB) , ... November 25, 2015 , ... ... a double board certified facial plastic surgeon specializing in both surgical and non-surgical ... of The Skin Spa at Hobgood Facial Plastic Surgery. , Highly trained ...
(Date:11/25/2015)... , ... November 25, 2015 , ... “While riding the ... inventor, from Bronx, N.Y. “I thought there had to be a convenient and comfortable ... PROTECTOR. , The PROTECTOR enables disabled individuals to safely travel during cold or inclement ...
(Date:11/25/2015)... ... 25, 2015 , ... "When I underwent breast reconstruction following ... uncomfortable," said an inventor from Bronx, N.Y. "In order to meet my own ... BRA for added comfort and support. The bra is easier to put on ...
Breaking Medicine News(10 mins):
(Date:11/25/2015)... , Nov. 25, 2015  Amgen (NASDAQ: ... License Application (BLA) with the United States ... ABP 501, a biosimilar candidate to Humira ® ... biosimilar application submitted to the FDA and represents Amgen,s ... Sean E. Harper , M.D., executive vice president ...
(Date:11/25/2015)... , Nov. 25, 2015  Linden Care, LLC, ... optimizing treatment outcomes for patients suffering from chronic pain, ... for a Temporary Restraining Order (TRO) enjoining Express Scripts ... two companies. --> --> ... all of its legal options. --> ...
(Date:11/25/2015)... 25, 2015 On Tuesday, November 24, ... trial against Wright Medical Technology, Inc. for product ... metal-on-metal hip implant device, awarded $11 million in ... week trial and three days of deliberations, the ... was defectively designed and unreasonably dangerous, and that ...
Breaking Medicine Technology: