Navigation Links
Novel Methods in Diagnosing Oral Cancer

Early diagnosis of oral cancer still remains the best way to ensure patient survival and quality of life, say researchers.// During the 85th General Session of the International Association for Dental Research, scientists from the University of California-Irvine presented two novel, non-invasive, ultra-fast images approaches to oral cancer detection, diagnostic screening, and mapping.

More than half of all oral cancer cases documented by the National Cancer Institute are diagnosed at an advanced stage. The five-year survival rate is 75% for those with localized disease at diagnosis, but only 16% for those with cancer metastasis.

Earlier detection of oral lesions would greatly improve the prognosis of these patients. Accurate delineation of lesion margins would ensure effective removal of all the tissue that presents a threat to the patient’s long-term health.

Two basic facts indicate that early detection of oral malignancy should be possible to a far greater extent than is currently seen:

(1) Accounting for 96% of all oral cancers, squamous cell carcinoma is often preceded by lesions on the oral mucosa. Malignant transformation, which is quite unpredictable, occurs in 1-90% of lesions over five years. Thus, oral cancer is often preceded by lesions, which are visible to the naked eye prior to transformation. A non-invasive diagnostic modality would permit regular monitoring of these lesions, detection of lesion transformation, and the identification of treatment needs at a very early, relatively harmless stage.

(2) High-risk populations are clearly defined: tobacco use, alcohol abuse, urban environment, specific ethnicities, poor diet, and frequent exposure to sunlight. A fast, mobile, relatively inexpensive and non-invasive diagnostic modality would permit the early detection and monitoring of oral lesions.

The researchers describe Three-dimensional Optical Coherence Tomography (3-D OCT) and Optical Doppler Tomo graphy (ODT), which show surface and subsurface tissues at near-microscopic levels of resolution, with the potential for replacing conventional surgical biopsy and histopathology techniques.

Combined with polarimetry, accurate delineation of lesion margins becomes possible. Scanning is painless and non-invasive, lasting less than one minute with a pen-sized hand-held probe.

This device’s resolution or diagnostic capability may dictate its primary use as an indicator of the need for biopsy.

Later, this modality may progressively reduce the need for biopsy, define surgical margins, and permit the direct evaluation of cancer treatments. In combination with OCT-visible molecular probes, this modality will greatly advance cancer diagnostics.

Source-Eurekalert
AN
'"/>




Related medicine news :

1. Novel "CYCLOSPORINE CAPSULE FORMULATION" to be launched
2. Novel biopsy technique for prostate cancer
3. Novel computer model for breast cancer
4. Novel research on liver cancer
5. Novel way to fight cancer
6. Novel test for bowel cancer
7. Novel Anti-Neutrophilic Effect produced by Salmeterol in mild asthma patients
8. Novel Therapy for Chronic Problem
9. Blood Sugar Kept In Control By Novel Protein
10. Novel antibiotic dressing developed for improved wound healing
11. United Kingdom Is Lagging In Novelty In The Field Of Pharmaceuticals
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/26/2017)... (PRWEB) , ... May 26, 2017 , ... Mediaplanet is ... Wound Care" campaign in USA Today, which will educate readers on how to take ... the campaign, a large focus is placed on melanoma. Dancing with the Stars professional, ...
(Date:5/26/2017)... Clara, Calif. (PRWEB) , ... May 26, 2017 ... ... announces the integration of the CareFusion NOX-T3 portable sleep monitor with its Somnoware ... provides a consistent, browser-based interface for diagnostic device operations. With this platform, initializing ...
(Date:5/26/2017)... , ... May 26, 2017 , ... After raising nearly ... Top gadget will continue to be available at a discounted crowdfunding price on ... stress wherever they are, I also wanted to bring a fidget toy to the ...
(Date:5/26/2017)... , ... May 26, 2017 , ... “When the Stars ... Home” is the creation of published author Laura Weigel Douglas, an avid reader who ... in a house that sometimes feels like Green Hills Adventure Camp. She couldn’t be ...
(Date:5/26/2017)... ... , ... Water damage to the flooring of several classrooms at The Fort ... with a number of critical issues to address before students could return to classes. ... little or no disruption to class schedules. Second, the project had to comply with ...
Breaking Medicine News(10 mins):
(Date:5/11/2017)... 11, 2017  Thornhill Research Inc. ( ... an $8,049,024 USD five-year, firm-fixed-priced, indefinite-quantity/indefinite-delivery contract by ... Commercial Corporation (CCC) ( Ottawa, Ontario, Canada ... administer general anesthesia to patients requiring emergency medical ... US Marine Corps have been a longtime partner ...
(Date:5/10/2017)... , May 10, 2017 Radiology has become ... its costs have also spiraled to the number one ... to radiology than ever before as the most complete ... a patient with lower back pain an MRI may ... reason for pain, resulting in entirely different treatment protocols.  ...
(Date:5/9/2017)... , May 9, 2017  Oramed Pharmaceuticals Inc. ... a clinical-stage pharmaceutical company focused on the development ... the Canadian Intellectual Property Office has granted Oramed ... Administration of Exenatide". The patent covers Oramed,s invention ... GLP-1 is an incretin hormone that stimulates ...
Breaking Medicine Technology: