Navigation Links
Non-invasive Screening in Early Pregnancy Halves Down's Syndrome Births

A recent research has found that non-invasive screening in early pregnancy reduces Down's syndrome births by 50 percent.

Professor Karen Brndum-Nielsen, of the Kennedy Institute, Glostrup, Denmark, has demonstrated that non-invasive screening of pregnant women with ultrasound early in pregnancy, combined with maternal blood analysis, has reduced the number of children born in Denmark with Down Syndrome by 50 percent.

Professor Brndum-Nielsen also explained that another advantage of the introduction of this practice in her country was a plunge in the number of invasive pre-natal diagnostic procedures from 11 percent to approx. 6 percent of pregnancies.

In September 2004, the National Board of Health in Denmark recommended new guidelines for prenatal diagnosis.

"Previously this was restricted to pregnant women over 35 years of age, but since the implementation of the new guidelines it has been available to any woman who wants it," Professor Brndum-Nielsen said.

The women were offered a measurement of nuchal translucency in the fetus by ultrasound. This test looks at thickness of the black space (fluid) in the neck area of the fetus. If there is more than the normal amount of fluid the risk of Down syndrome is increased. Likewise if there is a certain combination of serum markers in the maternal blood test, taken at the same time, there is the possibility of an increased risk of a chromosomal abnormality. The combined screening is carried out at 11 to 14 weeks of gestation.

Professor Brndum-Nielsen and her team looked at the effects of the new guidelines in 2004, 2005, and 2006, in 3 counties in Denmark with a total population of 1.1 million inhabitants, or about one-fifth of the population of the country. They compared these findings with national figures obtained from the Central Cytogenetic Registry, which confirmed the reduction in invasive procedures and the number of children born with Down syndrome a t national level.

"When we looked further at the history of children born with Down Syndrome, we found that their mothers had declined the offer of screening, or had taken it up too late in pregnancy", she says.

Women whose test results showed an elevated risk were offered an invasive procedure (chorionic villus sampling or amniocentesis) to certainly corroborate or exclude the diagnosis of Down syndrome by chromosome analysis.

"We found that making non-invasive screening available to all pregnant women meant that the numbers of invasive procedures decreased by 40% between 2004 and 2006", says Professor Brndum-Nielsen.

"Although we have not yet studied the whole of the population, these numbers are significant enough to show that the new guidelines have been accepted by a great majority of Danish parents. However, there is a need for analysis of the psychosocial aspects, both as to the pre-test counselling and the womens attitudes," she says.


'"/>




Related medicine news :

1. Horse Heart Coherence May Be Key To Non-invasive Stress Detection
2. Laser-based System for Non-invasive Diagnosis of Skin Cancers on the Anvil
3. Smart Pill for Non-invasive Diagnoses of Stomach Problems
4. MRE, An Accurate Tool for Non-invasive Diagnosis of Liver Diseases
5. Non-invasive Screening in Early Pregnancy Halves Downs Syndrome Births
6. Screening device for ovarian cancer
7. Screening bypasses radical breast surgery
8. Screening of Lazy Eye
9. Screening Cost-Effective for Lung Cancer
10. Screening Newborns Questioned
11. Screening For Prostate Cancer in men over 75 Questioned
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/25/2016)... , ... June 25, 2016 , ... "With 30 hand-drawn ... specific project," said Christina Austin - CEO of Pixel Film Studios. , ProHand ... all within Final Cut Pro X . Simply select a ProHand generator and ...
(Date:6/25/2016)... Oklahoma City, Oklahoma (PRWEB) , ... June 25, ... ... to helping both athletes and non-athletes recover from injury. Recently, he has implemented ... for the Oklahoma City area —Johnson is one of the first doctors to ...
(Date:6/24/2016)... ... 2016 , ... A recent article published June 14 on E ... goes on to state that individuals are now more comfortable seeking to undergo not ... as calf and cheek reduction. The Los Angeles area medical group, Beverly Hills Physicians ...
(Date:6/24/2016)... ... June 24, 2016 , ... Marcy was in a crisis. Her son James, eight, ... at his family verbally and physically. , “When something upset him, he couldn’t control his ... it. He would throw rocks at my other children and say he was going to ...
(Date:6/24/2016)... ... June 24, 2016 , ... Dr. Amanda ... orthodontic treatment. Dr. Cheng has extensive experience with all areas of orthodontics, including ... accelerated osteogenic orthodontics. , Micro-osteoperforation is a revolutionary adjunct to orthodontic treatment. ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)...  Collagen Matrix, Inc., ("Collagen Matrix") the driving ... collagen and mineral based medical devices for tissue ... Messer has joined the company as Vice ... growing portfolio of oral surgery, neurosurgery, orthopaedic and ... the Collagen Matrix executive team as an accomplished ...
(Date:6/24/2016)... June 24, 2016 The Academy of Managed ... recommendations that would allow biopharmaceutical companies to more ... that make formulary and coverage decisions, a move that ... new medicines. The recommendations address restrictions in ... on the drug label, a prohibition that hinders decision ...
(Date:6/24/2016)... --  Pulmatrix, Inc ., (NASDAQ: PULM ), ... today that it was added to the Russell Microcap ... set of U.S. and global equity indexes on June ... for Pulmatrix," said Chief Executive Officer Robert Clarke ... in developing drugs for crucial unmet medical needs, and ...
Breaking Medicine Technology: