Navigation Links
Non-invasive Screening in Early Pregnancy Halves Down's Syndrome Births

A recent research has found that non-invasive screening in early pregnancy reduces Down's syndrome births by 50 percent. Professor Karen Brndum-Nielsen, of the Kennedy Institute, Glostrup, Denmark, has demonstrated that non-invasive screening of pregnant women with ultrasound early in pregnancy, combined with maternal blood analysis, has reduced the number of children born in Denmark with Down Syndrome by 50 percent.

Professor Brndum-Nielsen also explained that another advantage of the introduction of this practice in her country was a plunge in the number of invasive pre-natal diagnostic procedures from 11 percent to approx. 6 percent of pregnancies.

In September 2004, the National Board of Health in Denmark recommended new guidelines for prenatal diagnosis. "Previously this was restricted to pregnant women over 35 years of age, but since the implementation of the new guidelines it has been available to any woman who wants it," Professor Brndum-Nielsen said.

The women were offered a measurement of nuchal translucency in the fetus by ultrasound. This test looks at thickness of the black space (fluid) in the neck area of the fetus. If there is more than the normal amount of fluid the risk of Down syndrome is increased. Likewise if there is a certain combination of serum markers in the maternal blood test, taken at the same time, there is the possibility of an increased risk of a chromosomal abnormality. The combined screening is carried out at 11 to 14 weeks of gestation.

Professor Brndum-Nielsen and her team looked at the effects of the new guidelines in 2004, 2005, and 2006, in 3 counties in Denmark with a total population of 1.1 million inhabitants, or about one-fifth of the population of the country. They compared these findings with national figures obtained from the Central Cytogenetic Registry, which confirmed the reduction in invasive procedures and the number of children born with Down syndrome at nati onal level.

"When we looked further at the history of children born with Down Syndrome, we found that their mothers had declined the offer of screening, or had taken it up too late in pregnancy", she says. Women whose test results showed an elevated risk were offered an invasive procedure (chorionic villus sampling or amniocentesis) to certainly corroborate or exclude the diagnosis of Down syndrome by chromosome analysis.

"We found that making non-invasive screening available to all pregnant women meant that the numbers of invasive procedures decreased by 40% between 2004 and 2006", says Professor Brndum-Nielsen.

"Although we have not yet studied the whole of the population, these numbers are significant enough to show that the new guidelines have been accepted by a great majority of Danish parents. However, there is a need for analysis of the psychosocial aspects, both as to the pre-test counselling and the womens attitudes," she says.


'"/>




Related medicine news :

1. Horse Heart Coherence May Be Key To Non-invasive Stress Detection
2. Laser-based System for Non-invasive Diagnosis of Skin Cancers on the Anvil
3. Smart Pill for Non-invasive Diagnoses of Stomach Problems
4. MRE, An Accurate Tool for Non-invasive Diagnosis of Liver Diseases
5. Non-invasive Screening in Early Pregnancy Halves Downs Syndrome Births
6. Screening device for ovarian cancer
7. Screening bypasses radical breast surgery
8. Screening of Lazy Eye
9. Screening Cost-Effective for Lung Cancer
10. Screening Newborns Questioned
11. Screening For Prostate Cancer in men over 75 Questioned
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/23/2017)... ... 23, 2017 , ... PreCheck, Inc., a background screening and ... with a three-year sales growth of 49 percent . The Inc. 5000 is ... comprehensive look at America’s independent entrepreneurs. This represents PreCheck’s fifth consecutive entry on ...
(Date:8/23/2017)... ... 23, 2017 , ... Silicon Valley Hair Institute, a leading San Francisco Bay ... The new rotation of archived blog posts can provide a wide selection of topics ... transplantation can review details online and then reach out for a no obligation consultation. ...
(Date:8/22/2017)... FRANCISCO BAY AREA, CA (PRWEB) , ... August ... ... premier, Nuvesse, an accessible luxurious collection of unique masks and serums that perfectly ... in scientific skin care advancements, at the 2017 Indie Beauty Expo on August ...
(Date:8/22/2017)... ... 22, 2017 , ... Each of the past six years, Lightning Labels has sent out a ... and stickers, demonstrating the variety and creativity of their designs. Submissions this year were open ... Now, it's time to announce the winners of the sixth annual Photo Contest, along with ...
(Date:8/22/2017)... ... ... “Wilderness Voices”: a collection of poetry inspired by life on a Kentucky farm ... author, Martha McKown, an ordained United Methodist minister with graduate degrees in Religious Education ... older sisters studied High School literature. She loved the early English folk ballads, ...
Breaking Medicine News(10 mins):
(Date:8/7/2017)... Aug. 7, 2017 Insightin Health, provider ... retention, and engagement, announced the selection of ... Product Development, effective as of February 2017. In this ... implementation strategy for our clients. Wood brings with ... consulting and business analytics within the healthcare industry. ...
(Date:8/7/2017)... DUBLIN , Aug. 7, 2017  Endo International ... has reached agreements to resolve virtually all known U.S. ... in discussions to resolve the known remaining U.S. claims ... installment payments beginning in the fourth quarter of 2017 ... part of its second quarter 2017 results, the Company ...
(Date:8/2/2017)... , Aug. 2, 2017 Fenita ... Who as a Pinnacle Lifetime Professional in the ... Account Manager at Turing Pharmaceuticals, AG. Her skills ... and relationship building.                ... than 25 years of experience as a highly ...
Breaking Medicine Technology: