Navigation Links
Non-Coding RNA Vital For Gene Activation And Protein Expression

Scientists at University of California have gained valuable insights about the differentiation of embryonic stem cells of fruit fly// , a finding that may eventually accelerate current research on stem cells and cancer.

The research is a joint effort by Dr. Frank Sauer (UCR Biochemistry Professor), Dr. Elisabeth Kremmer (Institut für Molekulare Immunologie, Munich) and other researchers from University of California. The results of the research titled, Noncoding RNAs of Trithorax Response Elements Recruit Drosophila Ash1 to Ultrabithrorax appears in the Science journal.

The research unravels how certain epigenetic activators, in this case Ash1 bind to the target DNA molecule to facilitate the activation of certain genes that play a crucial role in determination of cell function. The mechanism of recognition of a specific DNA sequence (target gene) by the epigenetic factors followed by binding and expression has remained poorly understood as of now.

The gene Ultrabithorax (Ubx) consists of Trithorax-reponse elements (TREs) that form the main target for binding of Ash1, the epigenetic activator. Subsequently, the non-coding RNA produced and retained at the TREs result in activation of the Ubx gene. The function of cells can be modified by transgenic transcription of non-coding TRE RNA.

Non-coding RNAs have been regarded to be inert, having a limited role in inducing expression or activation of genes followed by protein expression. The present research has highlighted that non-coding RNAs can have a wide range of functions than what is foreseen at the moment. Genetic manipulation techniques can be developed to activate rather than silence the so-called genetic junk to determine fate of a specific cell.

With our improved understanding of such complex mechanisms and sustained research efforts, we might someday be able to cure certain diseases such as cancer that are thought incurable.


'"/>




Page: 1

Related medicine news :

1. Fat Consumption Could Play A Vital Role In Affecting A Child’s Memory
2. Brain Plays Vital Role In Maintaining Bone Density
3. Sex Played A Vital Role For Evolution Of Infectious Diseases
4. Cancer Patient Denied Vital Drug
5. Telomerase Vital In Maintaining Ability of Stem Cell to Multiply
6. Parental Knowledge Of RSV Infections Is Vital
7. Calcium Receptor Vital For Stem Cell Migration to Bone Marrow
8. Aluminium and Iron Could Play a Vital Role in Multiple Sclerosis
9. Alcohol Consumption Pattern Plays A Vital Role in Alcohol Related Injury
10. Urban Built Environment May Play a Vital Role in Influencing the Body Size
11. Leptin Plays A Vital Role among Female Patients Suffering From Asthma
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/27/2016)... Lafayette, California (PRWEB) , ... ... ... a pioneer in the patient payment industry today announced its strategic partnership ... and health system workflows. , The two companies’ proven, proprietary technology combine ...
(Date:6/26/2016)... ... June 27, 2016 , ... Quality metrics are proliferating in cancer ... they remain in the eye of the beholder, according to experts who offered insights ... American Journal of Managed Care. For the full issue, click here . , ...
(Date:6/26/2016)... North Carolina (PRWEB) , ... June 26, 2016 , ... ... release of a new product that was developed to enhance the health of felines. ... for centuries. , The two main herbs in the PawPaws Cat Kidney Support ...
(Date:6/25/2016)... ... June 25, 2016 , ... ... and applications at AcademyHealth’s Annual Research Meeting June 26-28, 2016, at the Hynes ... important health care topics including advance care planning, healthcare costs and patient and ...
(Date:6/25/2016)... ... June 25, 2016 , ... "With 30 hand-drawn hand gesture animations, ... Christina Austin - CEO of Pixel Film Studios. , ProHand Cartoon’s package transforms ... Final Cut Pro X . Simply select a ProHand generator and drag it above ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... , June 23, 2016  MedSource announced today ... its e-clinical software solution of choice.  This latest ... possible value to their clients by offering a ... preferred relationship establishes nowEDC as the EDC platform ... MedSource,s full-service clients.  "nowEDC has long been a ...
(Date:6/23/2016)... Any dentist who has made an implant supported ... Many of them do not even offer this as a ... laboratory costs involved. And those who ARE able to offer ... high cost that the majority of today,s patients would not ... Zadeh , founder of Dental Evolutions Inc. and inventor of ...
(Date:6/23/2016)... startling report released today, National Safety Council research shows ... plan to eliminate prescription opioid overdoses. Prescription Nation ... the worst drug crisis in recorded U.S. history, assigned a "Making ... , New Mexico , Tennessee ... states, three – Michigan , Missouri ...
Breaking Medicine Technology: