Navigation Links
Non-Coding RNA Vital For Gene Activation And Protein Expression

Scientists at University of California have gained valuable insights about the differentiation of embryonic stem cells of fruit fly// , a finding that may eventually accelerate current research on stem cells and cancer.

The research is a joint effort by Dr. Frank Sauer (UCR Biochemistry Professor), Dr. Elisabeth Kremmer (Institut für Molekulare Immunologie, Munich) and other researchers from University of California. The results of the research titled, Noncoding RNAs of Trithorax Response Elements Recruit Drosophila Ash1 to Ultrabithrorax appears in the Science journal.

The research unravels how certain epigenetic activators, in this case Ash1 bind to the target DNA molecule to facilitate the activation of certain genes that play a crucial role in determination of cell function. The mechanism of recognition of a specific DNA sequence (target gene) by the epigenetic factors followed by binding and expression has remained poorly understood as of now.

The gene Ultrabithorax (Ubx) consists of Trithorax-reponse elements (TREs) that form the main target for binding of Ash1, the epigenetic activator. Subsequently, the non-coding RNA produced and retained at the TREs result in activation of the Ubx gene. The function of cells can be modified by transgenic transcription of non-coding TRE RNA.

Non-coding RNAs have been regarded to be inert, having a limited role in inducing expression or activation of genes followed by protein expression. The present research has highlighted that non-coding RNAs can have a wide range of functions than what is foreseen at the moment. Genetic manipulation techniques can be developed to activate rather than silence the so-called genetic junk to determine fate of a specific cell.

With our improved understanding of such complex mechanisms and sustained research efforts, we might someday be able to cure certain diseases such as cancer that are thought incurable.


'"/>




Page: 1

Related medicine news :

1. Fat Consumption Could Play A Vital Role In Affecting A Child’s Memory
2. Brain Plays Vital Role In Maintaining Bone Density
3. Sex Played A Vital Role For Evolution Of Infectious Diseases
4. Cancer Patient Denied Vital Drug
5. Telomerase Vital In Maintaining Ability of Stem Cell to Multiply
6. Parental Knowledge Of RSV Infections Is Vital
7. Calcium Receptor Vital For Stem Cell Migration to Bone Marrow
8. Aluminium and Iron Could Play a Vital Role in Multiple Sclerosis
9. Alcohol Consumption Pattern Plays A Vital Role in Alcohol Related Injury
10. Urban Built Environment May Play a Vital Role in Influencing the Body Size
11. Leptin Plays A Vital Role among Female Patients Suffering From Asthma
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/25/2016)... ... ... First Choice Emergency Room , the largest network of independent freestanding emergency ... its new Mesquite-Samuell Farm facility. , “We are pleased to announce Dr. Ogunleye ... M. Muzzarelli, Executive Medical Director of First Choice Emergency Room. , Dr. Ogunleye ...
(Date:6/25/2016)... ... June 25, 2016 , ... Dr. Calvin Johnson has ... he has implemented orthobiologic procedures as a method for treating his patients. The ... first doctors to perform the treatment. Orthobiologics are substances that orthopaedic surgeons use ...
(Date:6/25/2016)... ... June 25, 2016 , ... Conventional wisdom preaches the benefits ... terms of the latter, setting the bar too high can result in disappointment, perhaps ... slow progress toward their goal. , Research from PsychTests.com reveals that ...
(Date:6/24/2016)... ... June 24, 2016 , ... Those who have experienced traumatic events may ... to unhealthy avenues, such as drug or alcohol abuse, as a coping mechanism. To ... for healthy coping following a traumatic event. , Trauma sufferers tend to feel a ...
(Date:6/24/2016)... ... ... a crisis. Her son James, eight, was out of control. Prone to extreme mood shifts ... upset him, he couldn’t control his emotions,” remembers Marcy. “If there was a knife ... and say he was going to kill them. If we were driving on the ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... DUBLIN , June 24, 2016 ... "The World Market for Companion Diagnostic Tests" report to ... World Market for Companion Diagnostics The World ... diagnostic and personalized medicine diagnostics. Market analysis in the report ... Diagnostics Test Market (In Vitro Diagnostic Kits) by Region (N. ...
(Date:6/24/2016)... 2016  Arkis BioSciences, a leading innovator in ... durable cerebrospinal fluid treatments, today announced it has ... is led by Innova Memphis, followed by Angel ... investors.  Arkis, new financing will accelerate the commercialization ... release of its in-licensed Endexo® technology. ...
(Date:6/23/2016)... DUBLIN , June 23, 2016 ... the "Pharmaceutical Excipients Market by Type (Organic Chemical ... Preservative), Formulation (Oral, Topical, Coating, Parenteral) - Global Forecast ... The global pharmaceutical excipients ... 2021 at a CAGR of 6.1% in the forecast ...
Breaking Medicine Technology: