Navigation Links
Non-Coding RNA Vital For Gene Activation And Protein Expression

Scientists at University of California have gained valuable insights about the differentiation of embryonic stem cells of fruit fly// , a finding that may eventually accelerate current research on stem cells and cancer.

The research is a joint effort by Dr. Frank Sauer (UCR Biochemistry Professor), Dr. Elisabeth Kremmer (Institut für Molekulare Immunologie, Munich) and other researchers from University of California. The results of the research titled, Noncoding RNAs of Trithorax Response Elements Recruit Drosophila Ash1 to Ultrabithrorax appears in the Science journal.

The research unravels how certain epigenetic activators, in this case Ash1 bind to the target DNA molecule to facilitate the activation of certain genes that play a crucial role in determination of cell function. The mechanism of recognition of a specific DNA sequence (target gene) by the epigenetic factors followed by binding and expression has remained poorly understood as of now.

The gene Ultrabithorax (Ubx) consists of Trithorax-reponse elements (TREs) that form the main target for binding of Ash1, the epigenetic activator. Subsequently, the non-coding RNA produced and retained at the TREs result in activation of the Ubx gene. The function of cells can be modified by transgenic transcription of non-coding TRE RNA.

Non-coding RNAs have been regarded to be inert, having a limited role in inducing expression or activation of genes followed by protein expression. The present research has highlighted that non-coding RNAs can have a wide range of functions than what is foreseen at the moment. Genetic manipulation techniques can be developed to activate rather than silence the so-called genetic junk to determine fate of a specific cell.

With our improved understanding of such complex mechanisms and sustained research efforts, we might someday be able to cure certain diseases such as cancer that are thought incurable.


'"/>




Page: 1

Related medicine news :

1. Fat Consumption Could Play A Vital Role In Affecting A Child’s Memory
2. Brain Plays Vital Role In Maintaining Bone Density
3. Sex Played A Vital Role For Evolution Of Infectious Diseases
4. Cancer Patient Denied Vital Drug
5. Telomerase Vital In Maintaining Ability of Stem Cell to Multiply
6. Parental Knowledge Of RSV Infections Is Vital
7. Calcium Receptor Vital For Stem Cell Migration to Bone Marrow
8. Aluminium and Iron Could Play a Vital Role in Multiple Sclerosis
9. Alcohol Consumption Pattern Plays A Vital Role in Alcohol Related Injury
10. Urban Built Environment May Play a Vital Role in Influencing the Body Size
11. Leptin Plays A Vital Role among Female Patients Suffering From Asthma
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/21/2017)... ... ... The American Hospital Association (AHA) has elected Claire Zangerle, Chief Nurse Executive at ... Trustees for a three-year term beginning January 1, 2018. , The AHA ... committed to the improvement of health in their communities. Founded in 1898, the AHA ...
(Date:8/20/2017)... Sugar Land Texas (PRWEB) , ... August 20, ... ... to announce that the HIPAA ComplyPAK™ Compliance Management System has assisted ... American Institute of Certified Public Accountants, Service Organization Control Level 2 (AICPA SOC ...
(Date:8/19/2017)... ... 18, 2017 , ... Paragon and IOTA ... help the cannabis industry move towards greater legitimacy. By incorporating IOTA’s unique approach ... with lower fees. Paragon will build a fully verifiable database to track prescriptions, ...
(Date:8/19/2017)... ... August 19, 2017 , ... Yesterday, the President of the United States ... two sides. There are not two sides to hatred, bigotry, discrimination, and a white ... and the NPEIV stands against all forms of such hatred and discrimination in this ...
(Date:8/18/2017)... VA (PRWEB) , ... August 18, 2017 , ... More ... the Democratic Republic of Congo (DRC) thanks to an ambitious venture that conjoined the ... well as the generous support of the Liberty community. These shoes will save lives ...
Breaking Medicine News(10 mins):
(Date:8/17/2017)... -- MJAC2017 , the premier cannabis event devoted to ... its leading lineup. MJAC2017 is proud ... specializing in the development of pharmaceutical and consumer products, will ... The Green Organic Dutchman are gold sponsors for the event, ... ...
(Date:8/15/2017)... , Aug. 15, 2017   Mostyn Law and Gulf ... Houston, Texas . The Mostyn Law family ... 2 years. That is why Mostyn Law is partnering ... to show its appreciation. Blood supplies are running ... 5% short of hospital needs in August. That is why the ...
(Date:8/15/2017)... AccuGenomics, Inc., a diagnostic company based in ... the company has provided an AccuKit to the HIV ... Chapel Hill and to Qura Therapeutics for evaluation in ... HIV reservoir and viral expression in human CD4+ T ... Center is a joint initiative between the University of ...
Breaking Medicine Technology: