Navigation Links
No Lymphoma Risk From Rheumatoid Arthritis Drugs

There has been an increasing fear regarding the elevated risk of lymphoma associated with rheumatoid arthritis treatment// A new study by Swedish researchers has found that such treatments may not confer an increased susceptibility to cancer, the results of which can be seen in the latest issue of Arthritis & Rheumatism journal.

The risk of cancer has been found to increase with worsening of the chronic inflammatory process. In other words, a cause-effect relationship has been established with the disease severity and cancer risk. Infact the drugs given for symptomatic treatment of rheumatoid arthritis, which, prevent further progress of the inflammation may actually reduce the cancer risk.

Rheumatoid arthritis is a progressive disease, characterized by inflammation of joints resulting in pain, joint damage, immobility and finally disability. Nearly 2 million Americans have been diagnosed with the chronic disease, according to estimates by the Arthritis Foundation. Non-steroidal anti-inflammatory drugs (NSAIDs), disease-modifying anti-rheumatic drugs (DMARDs), biologic response modifiers (new generation drugs) and analgesics are currently being given for treatment.

The researchers studied data obtained from nearly 75,000 rheumatoid arthritis patients. Amongst these, 378 patients developed lymphoma during the course of treatment. The data obtained was compared with that obtained from 378 healthy controls. The severity of the disease (low, medium, high), the duration of the disease, the level of inflammation or tenderness in the joints was some of the factors taken into consideration.

The results of the analysis established that individuals with high activity (severe disease) had a 70-fold increased risk of developing lymphoma. The severity of involvement of knees, hands and feet within the first year of diagnosis was also found to confer an increased risk. The lymphoma risk was much lower (8 fold) in those who ha d medium disease activity.

Furthermore, no increased risk of lymphoma was found in those who were given anti-rheumatic drugs (DMARDS), including the drug methotrexate (anti-cancer drug). No increased risk could also be documented with use of steroids or NSAIDs. Surprisingly, the incidence of lymphoma in those who were given corticosteriods injections was the lowest, probably highlighting its role in cancer prevention.

The results of the present study highlight the need for early identification and aggressive treatment to prevent worsening of the disease. To conclude, the more severe the disease, the higher is the cancer risk. The provision of appropriate anti-rheumatic treatment can decrease the disease related complications.


'"/>




Related medicine news :

1. Lymphomas Link to Hepatitis C
2. New Guidelines For Assessing Lymphoma Treatment
3. A Novel Treatment for KSHV-infected Lymphomas
4. New treatment for Rheumatoid Arthritis
5. New Rheumatoid Arthritis Treatment
6. New Rheumatoid Arthritis Treatment
7. Consumption Of Red Meat Found To Double The Risk of Rheumatoid Arthritis
8. The Link Between Rheumatoid Arthritis And Heart Failure
9. Smoking during pregnancy increases risk of Rheumatoid Arthritis.
10. Good News For Those Of You Suffering From Rheumatoid Arthritis
11. Mineral Oil exposure increases risk of Rheumatoid Arthritis
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... Fairfax, VA (PRWEB) , ... October 13, 2017 ... ... provider of DevOps and Agile Software Development, has been awarded a contract by ... (EATS) Blanket Purchase Agreement (BPA) aims to accelerate the enterprise use of Agile ...
(Date:10/12/2017)... , ... October 12, 2017 , ... ... now treating sleep apnea using cutting-edge Oventus O2Vent technology. As many ... sleep disorder characterized by frequent cessation in breathing. Oral appliances can offer significant ...
(Date:10/12/2017)... MD (PRWEB) , ... October 12, 2017 , ... The ... of Excellence to Carol Friedman, PhD, FACMI, during the Opening Session of AMIA’s Annual ... – 8. , In honor of Morris F. Collen, a pioneer in the field ...
(Date:10/12/2017)... ... , ... HMP , a leader in healthcare events and education, today announced ... Award for ‘Best B-to-B Healthcare Website.’ Winners were announced during the Eddie & Ozzie ... competition recognizes editorial and design excellence across a range of sectors. This year’s program ...
(Date:10/12/2017)... , ... October 12, 2017 , ... ... the nation's first interactive health literacy software tool, and the Cancer Patient Education ... of cancer patient education, today announce a new strategic alliance. , As ...
Breaking Medicine News(10 mins):
(Date:10/5/2017)... 2017  In response to the nationwide opioid ... Surgeons (AAOMS) released prescribing recommendations that urge ibuprofen ... as a first-line therapy to manage a patient,s ... Recognizing the value and importance of ... Prescribing: Acute and Postoperative Pain Management" stresses that ...
(Date:10/4/2017)... , Oct. 4, 2017 ... single-use, self-contained, illuminating medical devices, today announced regulatory ... Health Surveillance Agency (or Agência Nacional de Vigilância ... first single-use, cordless surgical retractor with integrated LED ... optimal access, illumination and exposure of a tissue ...
(Date:10/2/2017)... ORLANDO, Fla. , Oct. 2, 2017  AllianceRx ... services company formed by Walgreens and pharmacy benefit manager ... of its new brand, which included the unveiling of ... Fla. , as well as at a few ... introduces the new brand to patients, some of whom ...
Breaking Medicine Technology: