Navigation Links
No Carrier Necessary: This Drug Delivers Itself

ndra Pandey, Ph.D., Distinguished Professor of Biophysical Sciences at RPCI and a co-author on the paper.

"This is a case where the easiest formulation works the best," added Indrajit Roy, Ph.D., UB research assistant professor of chemistry and another co-author.

The researchers found that because HPPH is amphiphillic, i.e., partially soluble in water and oil, nanocrystals of it will self-assemble, that is, in solution the molecules aggregate, but not into such big clusters that they settle to the bottom.

"It's a controlled formation of a colloidally stable suspension of nanosized crystals," explained Tymish Ohulchanskyy, Ph.D., UB senior research scientist and a co-author.

The researchers originally were investigating nanocrystals as a delivery method for hydrophobic dyes in bioimaging applications, another promising use for nanocrystals that they continue to pursue.

Further in vivo studies with HPPH nanocrystals are being conducted by scientists at UB and RPCI, including Pandey and Allan R. Oseroff, M.D., Ph.D., chair of the department of dermatology at RPCI and in UB's School of Medicine and Biomedical Sciences.

The UB/RPCI team is exploring the use of the same technique for delivering other hydrophobic drugs, including those used in chemotherapy.

Additional co-authors on the paper are Koichi Baba, Ph.D., former postdoctoral research associate in the UB Department of Chemistry, and Yihui Chen, Ph.D., postdoctoral research associate at RPCI.

The nanocrystal research was supported by the National Institutes of Health, the John R. Oishei Foundation and UB's New York State Center of Excellence in Bioinformatics and Life Sciences with additional support from RPCI.

In related work, the UB researchers have achieved improved depth penetration of HPPH using two-photon photodynamic therapy, research that recently was published in the Journal of the American Chemical
'"/>




Page: 1 2 3

Related medicine news :

1. Alzheimer Gene Carriers Found To Have Memory Problems
2. Fruit Bats Act As Carriers of Ebola Virus
3. Financial Allowances Being Offered To Poor Vietnamese HIV Carriers
4. Coffee Reduces Risk of Breast Cancer in BRCA1 Mutation Carriers
5. A Carrier Protein Associates With Human Insulin Resistance
6. Genital Herpes - No Symptoms But A Potent Carrier
7. New Carrier Developed To Deliver Drugs to Gliomas
8. HIV Carriers Join Hands to Fight for their Rights
9. HIV Carriers Form an Association to Fight Social Stigma in Jharkhand
10. Carriers With Alzheimers High Risk Gene Type Age Normally Until the Disease Strikes
11. Woman Delivers Identical Quadruplets
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Carrier Necessary This Drug Delivers Itself

(Date:7/29/2015)... ... 29, 2015 , ... Sports fans young and old at the National Cherry ... the Detroit Lions, joined by A Forever Recovery, a holistic treatment center for substance ... Moore, Pro Bowl Offensive Lineman Lomas Brown, and Tight End Rob Rubick signed foam ...
(Date:7/29/2015)... (PRWEB) , ... July 29, 2015 , ... This past ... a positive surrogacy journey from a treasured member of the CARE extended family. ... Vallarta hopes to help intended parents across the globe gain a newfound perspective on ...
(Date:7/29/2015)... ... July 29, 2015 , ... The ... the impact drinking and substance abuse is having on lost productivity, workplace accidents ... in the billions per year. [1] Will Wesch, Director of Admissions for ...
(Date:7/29/2015)... ... July 29, 2015 , ... According to the The Media ... and are exposed to advertisements, for medicinal use are more likely to abuse the ... the use of marijuana is considered beneficial are more apt to use the substance, ...
(Date:7/29/2015)... (PRWEB) , ... July 29, 2015 , ... Join Luz ... and healthfulness. Gerber believes that Well-Being begins with understanding how the body actually works. ... state of healthfulness within. Guests will receive tips on how to forge this new ...
Breaking Medicine News(10 mins):Health News:A Forever Recovery Holds Autograph Event with Former Detroit Lions at Cherry Festival 2Health News:Heartfelt Interview Shows Extraordinary Impact of CARE Surrogacy Center Mexico 2Health News:Heartfelt Interview Shows Extraordinary Impact of CARE Surrogacy Center Mexico 3Health News:Workplace Trouble: Survey Reveals Sharp Escalation in Restaurant/Food Service Employee Drug Abuse 2Health News:Workplace Trouble: Survey Reveals Sharp Escalation in Restaurant/Food Service Employee Drug Abuse 3Health News:New Study Reveals Teens Use Marijuana More in States Where Marijuana Is Legalized 2Health News:New Study Reveals Teens Use Marijuana More in States Where Marijuana Is Legalized 3Health News:Pampering and Empowerment Abound at Final Event in Luz Delia Gerber’s Book Unveiling 2
... Institute for Child Health Research shows an association between ... research findings have just been published online in the ... of Nutrition studies at the Institute, Associate Professor Wendy ... 1800 adolescents from the long-term Raine Study and classified ...
... efforts may be much more sensitive than previously realized to ... scientists at Harvard University report this week. In some cases, ... the difference between a minor, localized outbreak and an epidemic ... Proceedings of the Royal Society B , comes amidst one ...
... HealthDay Reporter , WEDNESDAY, July 28 (HealthDay News) ... see someone having what appears to be a heart attack, ... can be as effective as CPR that includes mouth-to-mouth breathing, ... July 29 issue of the New England Journal of ...
... (TZDS), including rosiglitazone and pioglitazone, may be at increased ... for publication in The Endocrine Society,s Journal of ... taking both loop diuretics and TZDs may also be ... shows that increased fracture risk is associated with higher ...
... Reporter , WEDNESDAY, July 28 (HealthDay News) -- A ... of men with metastatic tumors resistant to standard hormonal ... Provenge (sipuleucel-T), improved survival by about four months compared ... However, with a round of treatment potentially costing $93,000, ...
... Serena Gordon HealthDay Reporter , WEDNESDAY, July 28 ... one day eliminate the need for the multiple daily finger ... their blood sugar levels. The new device was tested ... monitored their blood sugar without the need for daily recalibration. ...
Cached Medicine News:Health News:Western diet link to ADHD 2Health News:Small increases in vaccine cost can cause large gaps in protection 2Health News:Chest Compressions Alone Best With CPR 2Health News:Chest Compressions Alone Best With CPR 3Health News:Vaccine Boosts Survival for Men With Advanced Prostate Cancer: Study 2Health News:Vaccine Boosts Survival for Men With Advanced Prostate Cancer: Study 3Health News:Implantable Sensor Measures Blood Sugar Levels 2Health News:Implantable Sensor Measures Blood Sugar Levels 3
(Date:7/29/2015)... REDMOND, Washington , 29 luglio 2015 /PRNewswire/ ... tedesco ha scoperto che l,ingestione quotidiana del probiotico ... microbiota intestinale umano e modifica la produzione intestinale ... insulina. Lo studio riguardava la somministrazione quotidiana di ceppo ... ATCC SD-5865) in compresse utilizzando il sistema di ...
(Date:7/29/2015)... FOREST, Calif. , July 29, 2015 ... ("Cryoport" or the "Company"), the leading provider ... life sciences industry, serving markets including immunotherapies, ... vaccine manufacturers, animal health, and reproductive medicine, ... the sale of common stock and warrants (the ...
(Date:7/29/2015)... Heska Corporation (NASDAQ: HSKA - News; ... diagnostic and other specialty veterinary products , today reported financial ... Second Quarter 2015 Highlights with Prior Year Comparison: ... $1.829 million, from $917 thousand. , Blood Analyzer and ... , Core Companion Animal revenue was up 19% to ...
Breaking Medicine Technology:È stato clinicamente dimostrato che il probiotico L. reuteri di Nutraceutix regola il metabolismo insulinico intestinale 2Cryoport Completes $6.8 Million Equity Capital Raise 2Cryoport Completes $6.8 Million Equity Capital Raise 3Heska Reports Financial Results for the Second Quarter of 2015 2Heska Reports Financial Results for the Second Quarter of 2015 3Heska Reports Financial Results for the Second Quarter of 2015 4Heska Reports Financial Results for the Second Quarter of 2015 5Heska Reports Financial Results for the Second Quarter of 2015 6Heska Reports Financial Results for the Second Quarter of 2015 7Heska Reports Financial Results for the Second Quarter of 2015 8
... First Prostate Cancer Patients in Clinical... -- TEL AVIV, Israel, August 31, 2010 ... ... ... first_result; // Results are keyed by longUrl, so we need to grab the first one. for (var ...
... Kendle (Nasdaq: KNDL ), a ... Mark J. Roseman, D.Sc., as the Company,s new ... effective immediately. Dr. Roseman brings to Kendle more ... strategic account development experience in the clinical services ...
Cached Medicine Technology:Elbit Imaging Announces Insightec Treats First Prostate Cancer Patients in Clinical Trials 2Elbit Imaging Announces Insightec Treats First Prostate Cancer Patients in Clinical Trials 3Elbit Imaging Announces Insightec Treats First Prostate Cancer Patients in Clinical Trials 4Elbit Imaging Announces Insightec Treats First Prostate Cancer Patients in Clinical Trials 5Elbit Imaging Announces Insightec Treats First Prostate Cancer Patients in Clinical Trials 6Elbit Imaging Announces Insightec Treats First Prostate Cancer Patients in Clinical Trials 7Elbit Imaging Announces Insightec Treats First Prostate Cancer Patients in Clinical Trials 8Elbit Imaging Announces Insightec Treats First Prostate Cancer Patients in Clinical Trials 9Kendle Appoints Mark J. Roseman, D.Sc., Senior Vice President and Chief Marketing Officer 2Kendle Appoints Mark J. Roseman, D.Sc., Senior Vice President and Chief Marketing Officer 3
... Plus with C-Flex combines optional ... the comfort of C-Flex.With the ... Plus with C-Flex offers a ... sleep therapy by taking the ...
... with the integrated Everest system. With ... system will be functional for hours ... integrated heated humidifier. The Everest heated ... nights use, and the reservoir is ...
Chase micro-hemocrit tubes are manufactured from soda lime glass, packed in plastic vials with reclosable snap-lock caps to maintain cleanliness....
... Vivid 3 system is designed to address ... performance, and offer an even wider range ... the OR. From color flow imaging with ... new Vivid 3 offers a wealth of ...
Medicine Products: