Navigation Links
New vaccine for brain cancer

For 18 years, Keith Black, M.D., from Cedars-Sinai Medical Center in Los Angeles has been searching for an effective treatment for brain cancer. While his research moves forward, he’s helping patients live longer along the way.// Latest research involves an effective brain tumor vaccine.

Dr. Black says brain tumors try to hide proteins on the tumor cell surface that the immune system could use to recognize the tumor. By hiding these cells, brain tumors become difficult to eradicate. The first step of research strips these “hidden” proteins from tumor cells and then cultures them from a piece of a patient’s tumor that’s removed with surgery. Next, come dendritic cells. Dendritic cells make up a very small percentage of the white blood cells, but they are the most efficient cells for presenting foreign proteins to the immune system. After isolating the dendritic cells, researchers say, they essentially have developed a technique to put these proteins [that the tumor tries to “hide”] directly on these [dendritic cells] and allow these cells to present these back to the proteins to the immune system by giving these cells back under the skin just as a shot, like a vaccine.

Researchers say the killer immune cells then recognize it and divide into millions of powerful T-cells. Now, when they see the tumor with this protein on the surface, they will try to attack it and kill the tumor cell.

It sounds confusing, but it works. By giving this vaccine, patients are surviving longer. Early research suggests, when combined with chemotherapy, the vaccine increases the two-year survival of patients with grade IV glioblastomas -- the deadliest type of brain cancer -- from 5 percent to nearly 40 percent.

However specialist’s newest endeavor is to inject the vaccine directly into the tumor of patients whose cancer has recurred. In the first patient vaccinated this way, the tumor appears to be at least stabilizing. Ultimately, researchers say they hope that they will be able to eliminate the need for surgery altogether by combining this strategy with non-invasive strategies of destroying the tumor and ... just putting these cells right into the tumor to allow the tumor to be eradicated.

Another research found that age matters when predicting length of survival. Hence Younger patients with a grade IV tumor will do much better than a 70-year-old with a grade II tumor, so there’s something related to age that has a huge impact on the survival of these tumors.

Younger patients have more T-cells ... that can be called up to fight these tumors. That accounts for the entire age effect and the survival of these patients. We know that the immune system is really the reason why younger patients do much better with these aggressive tuors.
'"/>




Related medicine news :

1. New hope for cancer victims – will vaccine cure the deadly bug
2. New vaccine helps allergy and asthma patients
3. Man against HIV – new vaccine ready for human trials
4. New vaccine helps allergy and asthma patients
5. Development of AIDS vaccine -- Chiron Corp in talks with four Indian cos
6. HIV did not arise from polio vaccine
7. Double impact vaccine
8. High Demand for a child vaccine
9. A new vaccine for leukemia
10. Shortage of MMR vaccine
11. Anthrax vaccine produced
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:9/25/2017)... ... , ... Just ask anyone old enough to remember what it was like ... up and containing so much metal that jokes about radio reception abounded. But thanks ... barely be observed. As a result, it’s now a billion-dollar industry and is, in ...
(Date:9/25/2017)... ... September 25, 2017 , ... Tim Rial Agency of Burleson, TX announces the ... By working closely with nonprofit groups and community leaders, the agency hopes to bring ... worthy organizations, families and individuals. , Tim Rial, the owner of Tim Rial ...
(Date:9/25/2017)... ... September 25, 2017 , ... NCPDP Foundation ... that it has awarded a $40,000 grant to Johns Hopkins Medicine to address ... CancelRx enables prescribers to electronically cancel a prescription already submitted to a pharmacy. ...
(Date:9/25/2017)... ... September 25, 2017 , ... Bobbie Horowitz was hardly able ... multiple health issues. As a cabaret and theater producer, Horowitz would manage to get ... of transportation in New York City, so she had to take a cab everywhere. ...
(Date:9/25/2017)... Port Richey, FL (PRWEB) , ... September 25, 2017 , ... ... New Port Richey, Fla. location at 5304 Main Street as an interventional pain management ... of the spine and extremities. He joins PPOA from private practice In Brooksville, Fla. ...
Breaking Medicine News(10 mins):
(Date:9/6/2017)... , Sept. 6, 2017 NeuroRx, a clinical ... Suicidal Ideation and Behavior (ASIB), has been granted Fast Track ... sequential therapy of NRX-100 (ketamine HCl) followed by NRX-101 (D-cycloserine ... a pivotal trial of this sequential therapy targeting patients who ... 1 ...
(Date:9/5/2017)... 2017  Just 18 months after its February 2016 ... announce the appointment of three new senior people to ... Dominic Jones-Phillips and James Wright bring ... Tammy Wynne joins as ... writers. She has over ten years, experience in global ...
(Date:8/31/2017)... Aug. 31, 2017 PM360,s annual Innovations ... to the latest innovations happening across the industry. Established ... to focus on providing a comprehensive look at the ... covers the most innovative companies, startups, divisions, products, services, ... "Everyone in this industry wants to ...
Breaking Medicine Technology: